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Upregulation of SYNGAP1 expression in mice and human neurons by redirecting alternative splicing

Neuron (Cambridge, Mass.), 2023-05, Vol.111 (10), p.1637-1650.e5

2023

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EZH2-Mediated Downregulation of the Tumor Suppressor DAB2IP Maintains Ovarian Cancer Stem Cells

Cancer research (Chicago, Ill.), 2020-10, Vol.80 (20), p.4371-4385

2020

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DNMT3A facilitates colorectal cancer progression via regulating DAB2IP mediated MEK/ERK activation

Biochimica et biophysica acta. Molecular basis of disease, 2022-04, Vol.1868 (4), p.166353-166353, Article 166353

2022

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AKT‐phosphorylated FOXO1 suppresses ERK activation and chemoresistance by disrupting IQGAP1‐MAPK interaction

The EMBO journal, 2017-04, Vol.36 (8), p.995-1010

2017

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Essential Roles for Dok2 and RasGAP in CD200 Receptor-Mediated Regulation of Human Myeloid Cells

The Journal of immunology (1950), 2009-10, Vol.183 (8), p.4879-4886

2009

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Diversity of mechanisms in Ras-GAP catalysis of guanosine triphosphate hydrolysis revealed by molecular modeling

Organic & biomolecular chemistry, 2019-05, Vol.17 (19), p.4879-4891

2019

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IQGAP1 and its binding proteins control diverse biological functions

Cellular signalling, 2012-04, Vol.24 (4), p.826-834

2012

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Ubiquitination of the scaffold protein IQGAP1 diminishes its interaction with and activation of the Rho GTPase CDC42

The Journal of biological chemistry, 2020-04, Vol.295 (15), p.4822-4835

2020

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Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions

Nature communications, 2019-09, Vol.10 (1), p.3975-13, Article 3975

2019

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The scaffold-protein IQGAP1 enhances and spatially restricts the actin-nucleating activity of Diaphanous-related formin 1 (DIAPH1)

The Journal of biological chemistry, 2020-03, Vol.295 (10), p.3134-3147

2020

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Hydrolysis of Guanosine Triphosphate (GTP) by the Ras·GAP Protein Complex: Reaction Mechanism and Kinetic Scheme

The journal of physical chemistry. B, 2015-10, Vol.119 (40), p.12838-12845

2015

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Ras-Specific GTPase-Activating Proteins-Structures, Mechanisms, and Interactions

Cold Spring Harbor perspectives in medicine, 2019-03, Vol.9 (3), p.a031500

2019

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The RasGAP Gene, RASAL2, Is a Tumor and Metastasis Suppressor

Cancer cell, 2013-09, Vol.24 (3), p.365-378

2013

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P120-Ras GTPase activating protein (RasGAP): A multi-interacting protein in downstream signaling

Biochimie, 2009-03, Vol.91 (3), p.320-328

2009

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The IQGAP scaffolds: Critical nodes bridging receptor activation to cellular signaling

The Journal of cell biology, 2023-06, Vol.222 (6), p.1

2023

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IQGAP1 promotes pancreatic cancer progression and epithelial-mesenchymal transition (EMT) through Wnt/β-catenin signaling

Scientific reports, 2019-05, Vol.9 (1), p.7539-12, Article 7539

2019

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Inhibition of polar actin assembly by astral microtubules is required for cytokinesis

Nature communications, 2021-04, Vol.12 (1), p.2409-2409, Article 2409

2021

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Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis

Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (6), p.2485-2490

2010

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Inhibition of Cdc42 during mitotic exit is required for cytokinesis

The Journal of cell biology, 2013-07, Vol.202 (2), p.231-240

2013

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RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice

The Journal of clinical investigation, 2012-02, Vol.122 (2), p.733-747

2012

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Identification and validation of seven new loci showing differential DNA methylation related to serum lipid profile: an epigenome-wide approach. The REGICOR study

Human molecular genetics, 2016-10, Vol.25 (20), p.4556-4565

2016

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DAB2IP suppresses tumor malignancy by inhibiting GRP75-driven p53 ubiquitination in colon cancer

Cancer letters, 2022-04, Vol.532, p.215588-215588, Article 215588

2022

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Infiltrative Vessel Co-optive Growth Pattern Induced by IQGAP3 Overexpression Promotes Microvascular Invasion in Hepatocellular Carcinoma

Clinical cancer research, 2024-05, Vol.30 (10), p.2206-2224

2024

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IQGAP3, a novel effector of Rac1 and Cdc42, regulates neurite outgrowth

Journal of cell science, 2007-02, Vol.120 (4), p.567-577

2007

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Upregulation of SYNGAP1 expression in mice and human neurons by redirecting alternative splicing

EZH2-Mediated Downregulation of the Tumor Suppressor DAB2IP Maintains Ovarian Cancer Stem Cells

DNMT3A facilitates colorectal cancer progression via regulating DAB2IP mediated MEK/ERK activation

AKT‐phosphorylated FOXO1 suppresses ERK activation and chemoresistance by disrupting IQGAP1‐MAPK interaction

Essential Roles for Dok2 and RasGAP in CD200 Receptor-Mediated Regulation of Human Myeloid Cells

Diversity of mechanisms in Ras-GAP catalysis of guanosine triphosphate hydrolysis revealed by molecular modeling

IQGAP1 and its binding proteins control diverse biological functions

Ubiquitination of the scaffold protein IQGAP1 diminishes its interaction with and activation of the Rho GTPase CDC42

Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions

The scaffold-protein IQGAP1 enhances and spatially restricts the actin-nucleating activity of Diaphanous-related formin 1 (DIAPH1)

Hydrolysis of Guanosine Triphosphate (GTP) by the Ras·GAP Protein Complex: Reaction Mechanism and Kinetic Scheme

Ras-Specific GTPase-Activating Proteins-Structures, Mechanisms, and Interactions

The RasGAP Gene, RASAL2, Is a Tumor and Metastasis Suppressor

P120-Ras GTPase activating protein (RasGAP): A multi-interacting protein in downstream signaling

The IQGAP scaffolds: Critical nodes bridging receptor activation to cellular signaling

IQGAP1 promotes pancreatic cancer progression and epithelial-mesenchymal transition (EMT) through Wnt/β-catenin signaling

Inhibition of polar actin assembly by astral microtubules is required for cytokinesis

Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis

Inhibition of Cdc42 during mitotic exit is required for cytokinesis

RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice

Identification and validation of seven new loci showing differential DNA methylation related to serum lipid profile: an epigenome-wide approach. The REGICOR study

DAB2IP suppresses tumor malignancy by inhibiting GRP75-driven p53 ubiquitination in colon cancer

Mutations in SYNGAP1 Cause Intellectual Disability, Autism, and a Specific Form of Epilepsy by Inducing Haploinsufficiency

Infiltrative Vessel Co-optive Growth Pattern Induced by IQGAP3 Overexpression Promotes Microvascular Invasion in Hepatocellular Carcinoma

IQGAP3, a novel effector of Rac1 and Cdc42, regulates neurite outgrowth

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