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Astragaloside IV exerts angiogenesis and cardioprotection after myocardial infarction via regulating PTEN/PI3K/Akt signaling pathway

Life sciences (1973), 2019-06, Vol.227, p.82-93

2019

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Astragaloside IV inhibits adriamycin-induced cardiac ferroptosis by enhancing Nrf2 signaling

Molecular and cellular biochemistry, 2021-07, Vol.476 (7), p.2603-2611

2021

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Combination of tanshinone IIA and astragaloside IV attenuate atherosclerotic plaque vulnerability in ApoE(-/-) mice by activating PI3K/AKT signaling and suppressing TRL4/NF-κB signaling

Biomedicine & pharmacotherapy, 2020-03, Vol.123, p.109729-109729, Article 109729

2020

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The Role of Astragaloside IV against Cerebral Ischemia/Reperfusion Injury: Suppression of Apoptosis via Promotion of P62-LC3-Autophagy

Molecules (Basel, Switzerland), 2019-05, Vol.24 (9), p.1838

2019

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Highly Efficient Biotransformation of Astragaloside IV to Cycloastragenol by Sugar-Stimulated β-Glucosidase and β-Xylosidase from Dictyoglomus thermophilum

Journal of microbiology and biotechnology, 2019-12, Vol.29 (12), p.1882-1893

2019

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Plant Natural Products for Human Health

2019

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Astragalus species: Phytochemistry, biological actions and molecular mechanisms underlying their potential neuroprotective effects on neurological diseases

Phytochemistry (Oxford), 2022-10, Vol.202, p.113293-113293, Article 113293

2022

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Astragaloside IV improves vascular endothelial dysfunction by inhibiting the TLR4/NF-κB signaling pathway

Life sciences (1973), 2018-09, Vol.209, p.111-121

2018

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A network pharmacology-based study on the mechanism of astragaloside IV alleviating renal fibrosis through the AKT1/GSK-3β pathway

Journal of ethnopharmacology, 2022-10, Vol.297, p.115535-115535, Article 115535

2022

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Integrative transcriptomics and proteomics analysis reveal the protection of Astragaloside IV against myocardial fibrosis by regulating senescence

European journal of pharmacology, 2024-07, Vol.975, p.176632-176632, Article 176632

2024

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Hypoxia- Inducible Factor-1α promotes the therapeutic effect of Astragaloside IV on hypertension

Acta Poloniae pharmaceutica, 2022-11, Vol.79 (4), p.487-495

2022

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Spatial-resolved metabolomics reveals tissue-specific metabolic reprogramming in diabetic nephropathy by using mass spectrometry imaging

Acta pharmaceutica Sinica. B, 2021-11, Vol.11 (11), p.3665-3677

2021

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Astragaloside IV, as a potential anticancer agent

Frontiers in pharmacology, 2023-02, Vol.14, p.1065505-1065505

2023

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Astragaloside IV regulates the ferroptosis signaling pathway via the Nrf2/SLC7A11/GPX4 axis to inhibit PM2.5-mediated lung injury in mice

International immunopharmacology, 2022-11, Vol.112, p.109186, Article 109186

2022

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Astragaloside IV inhibits lung cancer progression and metastasis by modulating macrophage polarization through AMPK signaling

Journal of experimental & clinical cancer research, 2018-08, Vol.37 (1), p.207-16, Article 207

2018

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Astragaloside IV ameliorates sepsis-induced myocardial dysfunction by regulating NOX4/JNK/BAX pathway

Life sciences (1973), 2022-12, Vol.310, p.121123-121123, Article 121123

2022

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Astragaloside IV regulates differentiation and induces apoptosis of activated CD4+ T cells in the pathogenesis of experimental autoimmune encephalomyelitis

Toxicology and applied pharmacology, 2019-01, Vol.362, p.105-115

2019

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Protective effects of Astragaloside IV on endoplasmic reticulum stress-induced renal tubular epithelial cells apoptosis in type 2 diabetic nephropathy rats

Biomedicine & pharmacotherapy, 2019-01, Vol.109, p.84-92

2019

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Molecular mechanisms of astragaloside‑IV in cancer therapy (Review)

International journal of molecular medicine, 2021-03, Vol.47 (3), Article 13

2021

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Astragaloside IV alleviates lung inflammation in Klebsiella pneumonia rats by suppressing TGF-β1/Smad pathway

Brazilian journal of medical and biological research, 2023, Vol.56, p.e12203-e12203

2023

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Astragaloside IV attenuate MI-induced myocardial fibrosis and cardiac remodeling by inhibiting ROS/caspase-1/GSDMD signaling pathway

Cell cycle (Georgetown, Tex.), 2022-11, Vol.21 (21), p.2309-2322

2022

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Astragaloside IV Alleviates Tacrolimus-Induced Chronic Nephrotoxicity via p62-Keap1-Nrf2 Pathway

Frontiers in pharmacology, 2021-01, Vol.11, p.610102

2021

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Astragaloside IV promotes microglia/macrophages M2 polarization and enhances neurogenesis and angiogenesis through PPARγ pathway after cerebral ischemia/reperfusion injury in rats

International immunopharmacology, 2021-03, Vol.92, p.107335-107335, Article 107335

2021

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Exploration of molecular mechanism underlying protective effect of astragaloside IV against radiation-induced lung injury by suppressing ferroptosis

Archives of biochemistry and biophysics, 2023-09, Vol.745, p.109717-109717, Article 109717

2023

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Research review on the pharmacological effects of astragaloside IV

Fundamental & clinical pharmacology, 2017-02, Vol.31 (1), p.17-36

2017

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Astragaloside IV exerts angiogenesis and cardioprotection after myocardial infarction via regulating PTEN/PI3K/Akt signaling pathway

Astragaloside IV inhibits adriamycin-induced cardiac ferroptosis by enhancing Nrf2 signaling

Combination of tanshinone IIA and astragaloside IV attenuate atherosclerotic plaque vulnerability in ApoE(-/-) mice by activating PI3K/AKT signaling and suppressing TRL4/NF-κB signaling

The Role of Astragaloside IV against Cerebral Ischemia/Reperfusion Injury: Suppression of Apoptosis via Promotion of P62-LC3-Autophagy

Highly Efficient Biotransformation of Astragaloside IV to Cycloastragenol by Sugar-Stimulated β-Glucosidase and β-Xylosidase from Dictyoglomus thermophilum

Plant Natural Products for Human Health

Astragalus species: Phytochemistry, biological actions and molecular mechanisms underlying their potential neuroprotective effects on neurological diseases

Astragaloside IV improves vascular endothelial dysfunction by inhibiting the TLR4/NF-κB signaling pathway

A network pharmacology-based study on the mechanism of astragaloside IV alleviating renal fibrosis through the AKT1/GSK-3β pathway

Integrative transcriptomics and proteomics analysis reveal the protection of Astragaloside IV against myocardial fibrosis by regulating senescence

Hypoxia- Inducible Factor-1α promotes the therapeutic effect of Astragaloside IV on hypertension

Spatial-resolved metabolomics reveals tissue-specific metabolic reprogramming in diabetic nephropathy by using mass spectrometry imaging

Astragaloside IV, as a potential anticancer agent

Astragaloside IV regulates the ferroptosis signaling pathway via the Nrf2/SLC7A11/GPX4 axis to inhibit PM2.5-mediated lung injury in mice

Astragaloside IV inhibits lung cancer progression and metastasis by modulating macrophage polarization through AMPK signaling

Astragaloside IV ameliorates sepsis-induced myocardial dysfunction by regulating NOX4/JNK/BAX pathway

Astragaloside IV regulates differentiation and induces apoptosis of activated CD4+ T cells in the pathogenesis of experimental autoimmune encephalomyelitis

Protective effects of Astragaloside IV on endoplasmic reticulum stress-induced renal tubular epithelial cells apoptosis in type 2 diabetic nephropathy rats

Molecular mechanisms of astragaloside‑IV in cancer therapy (Review)

Astragaloside IV alleviates lung inflammation in Klebsiella pneumonia rats by suppressing TGF-β1/Smad pathway

Astragaloside IV attenuate MI-induced myocardial fibrosis and cardiac remodeling by inhibiting ROS/caspase-1/GSDMD signaling pathway

Astragaloside IV Alleviates Tacrolimus-Induced Chronic Nephrotoxicity via p62-Keap1-Nrf2 Pathway

Astragaloside IV promotes microglia/macrophages M2 polarization and enhances neurogenesis and angiogenesis through PPARγ pathway after cerebral ischemia/reperfusion injury in rats

Exploration of molecular mechanism underlying protective effect of astragaloside IV against radiation-induced lung injury by suppressing ferroptosis

Research review on the pharmacological effects of astragaloside IV

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