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Mitochondrial uncoupling and the disruption of the metabolic network in hepatocellular carcinoma

Oncotarget, 2020-08, Vol.11 (31), p.3013-3024

2020

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Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4)

Organic & biomolecular chemistry, 2017-09, Vol.15 (36), p.7623-7629

2017

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N,N′-diaryl-bishydrazones in a biphenyl platform: Broad spectrum antifungal agents

European journal of medicinal chemistry, 2019-02, Vol.164, p.273-281

2019

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2′,6′-Dihalostyrylanilines, Pyridines, and Pyrimidines for the Inhibition of the Catalytic Subunit of Methionine S‑Adenosyltransferase‑2

Journal of medicinal chemistry, 2014-07, Vol.57 (14), p.6083-6091

2014

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Pictet-Spengler condensations using 4-(2-aminoethyl)coumarins

New journal of chemistry, 2020-08, Vol.44 (31), p.13415-13429

2020

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Semisynthetic aurones inhibit tubulin polymerization at the colchicine-binding site and repress PC-3 tumor xenografts in nude mice and myc-induced T-ALL in zebrafish

Scientific reports, 2019-04, Vol.9 (1), p.6439-6439, Article 6439

2019

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Fluorinated N,N'-Diarylureas As Novel Therapeutic Agents Against Cancer Stem Cells

Molecular cancer therapeutics, 2017-05, Vol.16 (5), p.831-837

2017

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Mathematical modeling of intracrine androgen metabolism in prostate cancer: Methodological aspects

The Prostate, 2018-10, Vol.78 (14), p.1069-1076

2018

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Abstract 1222: Fluorinated N, N-diarylureas treatment as effective strategy to target colorectal cancer stem cells

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.1222-1222

2016

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Analysis of trans-2,6-difluoro-4′-(N,N-dimethylamino)stilbene (DFS) in biological samples by liquid chromatography-tandem mass spectrometry: metabolite identification and pharmacokinetics

Analytical and bioanalytical chemistry, 2015-09, Vol.407 (24), p.7319-7332

2015

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A Direct Synthesis of 2‐(ω‐Carboxyalkyl)isoflavones from ortho‐Hydroxylated Deoxybenzoins

European journal of organic chemistry, 2018-10, Vol.2018 (39), p.5460-5463

2018

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Synthesis and tautomerization of hydroxylated isoflavones bearing heterocyclic hemi-aminals

Organic & biomolecular chemistry, 2015-01, Vol.13 (4), p.1053-1067

2015

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Application of Mannich bases to the synthesis of hydroxymethylated isoflavonoids as potential antineoplastic agents

Organic & biomolecular chemistry, 2015-12, Vol.13 (46), p.11292-11301

2015

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Fluorinated N,N‑Dialkylaminostilbenes Repress Colon Cancer by Targeting Methionine S‑Adenosyltransferase 2A

ACS chemical biology, 2013-04, Vol.8 (4), p.796-803

2013

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Par-4 secretion: stoichiometry of 3-arylquinoline binding to vimentin

Organic & biomolecular chemistry, 2016-01, Vol.14 (1), p.74-84

2016

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Bis(N-amidinohydrazones) and N-(amidino)-N′-aryl-bishydrazones: New classes of antibacterial/antifungal agents

Bioorganic & medicinal chemistry, 2017-01, Vol.25 (1), p.58-66

2017

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N-Aryl benzenesulfonamide inhibitors of [3H]-thymidine incorporation and β-catenin signaling in human hepatocyte-derived Huh-7 carcinoma cells

Bioorganic & medicinal chemistry letters, 2015-09, Vol.25 (18), p.3897-3899

2015

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Application of the 4D Fingerprint Method with a Robust Scoring Function for Scaffold-Hopping and Drug Repurposing Strategies

Journal of chemical information and modeling, 2014-10, Vol.54 (10), p.2834-2845

2014

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Crizotinib induces Par-4 secretion from normal cells and GRP78 expression on the cancer cell surface for selective tumor growth inhibition

American journal of cancer research, 2023-01, Vol.13 (3), p.976-991

2023

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Antineoplastic Isoflavonoids Derived from Intermediate ortho-Quinone Methides Generated from Mannich Bases

ChemMedChem, 2016-03, Vol.11 (6), p.600-611

2016

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Inhibition of dihydrotestosterone synthesis in prostate cancer by combined frontdoor and backdoor pathway blockade

Oncotarget, 2018-02, Vol.9 (13), p.11227-11242

2018

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Novel Mycosin Protease MycP1 Inhibitors Identified by Virtual Screening and 4D Fingerprints

Journal of chemical information and modeling, 2014-04, Vol.54 (4), p.1166-1173

2014

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Pentapeptide boronic acid inhibitors of Mycobacterium tuberculosis MycP1 protease

Bioorganic & medicinal chemistry letters, 2014-08, Vol.24 (15), p.3546-3548

2014

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Development of 6H-chromeno[3,4-c]pyrido[3′,2′:4,5]thieno[2,3-e]pyridazin-6-ones as Par-4 secretagogues

Tetrahedron letters, 2015-06, Vol.56 (23), p.3382-3384

2015

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Halogenated diarylacetylenes repress c-myc expression in cancer cells

Bioorganic & medicinal chemistry letters, 2014-08, Vol.24 (15), p.3638-3640

2014

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Mitochondrial uncoupling and the disruption of the metabolic network in hepatocellular carcinoma

Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4)

N,N′-diaryl-bishydrazones in a biphenyl platform: Broad spectrum antifungal agents

2′,6′-Dihalostyrylanilines, Pyridines, and Pyrimidines for the Inhibition of the Catalytic Subunit of Methionine S‑Adenosyltransferase‑2

Pictet-Spengler condensations using 4-(2-aminoethyl)coumarins

Semisynthetic aurones inhibit tubulin polymerization at the colchicine-binding site and repress PC-3 tumor xenografts in nude mice and myc-induced T-ALL in zebrafish

Fluorinated N,N'-Diarylureas As Novel Therapeutic Agents Against Cancer Stem Cells

Mathematical modeling of intracrine androgen metabolism in prostate cancer: Methodological aspects

Abstract 1222: Fluorinated N, N-diarylureas treatment as effective strategy to target colorectal cancer stem cells

Analysis of trans-2,6-difluoro-4′-(N,N-dimethylamino)stilbene (DFS) in biological samples by liquid chromatography-tandem mass spectrometry: metabolite identification and pharmacokinetics

A Direct Synthesis of 2‐(ω‐Carboxyalkyl)isoflavones from ortho‐Hydroxylated Deoxybenzoins

Synthesis and tautomerization of hydroxylated isoflavones bearing heterocyclic hemi-aminals

Application of Mannich bases to the synthesis of hydroxymethylated isoflavonoids as potential antineoplastic agents

Fluorinated N,N‑Dialkylaminostilbenes Repress Colon Cancer by Targeting Methionine S‑Adenosyltransferase 2A

Par-4 secretion: stoichiometry of 3-arylquinoline binding to vimentin

Bis(N-amidinohydrazones) and N-(amidino)-N′-aryl-bishydrazones: New classes of antibacterial/antifungal agents

N-Aryl benzenesulfonamide inhibitors of [3H]-thymidine incorporation and β-catenin signaling in human hepatocyte-derived Huh-7 carcinoma cells

Application of the 4D Fingerprint Method with a Robust Scoring Function for Scaffold-Hopping and Drug Repurposing Strategies

Crizotinib induces Par-4 secretion from normal cells and GRP78 expression on the cancer cell surface for selective tumor growth inhibition

Antineoplastic Isoflavonoids Derived from Intermediate ortho-Quinone Methides Generated from Mannich Bases

Inhibition of dihydrotestosterone synthesis in prostate cancer by combined frontdoor and backdoor pathway blockade

Novel Mycosin Protease MycP1 Inhibitors Identified by Virtual Screening and 4D Fingerprints

Pentapeptide boronic acid inhibitors of Mycobacterium tuberculosis MycP1 protease

Development of 6H-chromeno[3,4-c]pyrido[3′,2′:4,5]thieno[2,3-e]pyridazin-6-ones as Par-4 secretagogues

Halogenated diarylacetylenes repress c-myc expression in cancer cells

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