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Significance of Glycine 478 in the Metabolism of N-Benzyl-1-aminobenzotriazole to Reactive Intermediates by Cytochrome P450 2B1

Biochemistry (Easton), 1997-09, Vol.36 (39), p.11707-11716

1997

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The use of 18 O‐exchange and base‐catalyzed N ‐dealkylation with liquid chromatography/tandem mass spectrometry to identify carbinolamide metabolites

Rapid communications in mass spectrometry, 2010-07, Vol.24 (14), p.2151-2161

2010

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Metabolic activation of the nontricyclic antidepressant trazodone to electrophilic quinone-imine and epoxide intermediates in human liver microsomes and recombinant P4503A4

Chemico-biological interactions, 2005-06, Vol.155 (1), p.10-20

2005

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MT FdR: a ferredoxin reductase from M. tuberculosis that couples to MT CYP51

Biochimica et biophysica acta, 2005-04, Vol.1707 (2), p.157-169

2005

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Cytochrome P450: progress and predictions

The FASEB journal, 1992-01, Vol.6 (2), p.669-673

1992

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Olefin formation in the oxidative deformylation of aldehydes by cytochrome P-450. Mechanistic implications for catalysis by oxygen-derived peroxide [Erratum to document cited in CA115(5):48632c]

Journal of the American Chemical Society, 1991-11, Vol.113 (23), p.9009-9009

1991

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Catalysis by Cytochrome P-450 of an Oxidative Reaction in Xenobiotic Aldehyde Metabolism: Deformylation with Olefin Formation

Proceedings of the National Academy of Sciences - PNAS, 1991-10, Vol.88 (20), p.8963-8966

1991

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A convenient and simple method for the .alpha.'-chlorination of .alpha.,.beta. and conjugated ketones

Journal of organic chemistry, 1984-04, Vol.49 (7), p.1286-1288

1984

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Metabolic Activation of trans-4-Hydroxy-2-nonenal, a Toxic Product of Membrane Lipid Peroxidation and Inhibitor of P450 Cytochromes

The Journal of biological chemistry, 1997-09, Vol.272 (36), p.22611-22616

1997

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In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent lefluonomide to its active alpha-cyanoenol metabolite A771726: mechanistic similarities with the cytochrome P450-catalyzed dehydration of aldoximes

Drug metabolism and disposition, 2003-10, Vol.31 (10), p.1240

2003

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Evidence for a Role of a Perferryl-Oxygen Complex, FeO3+, in the N-Oxygenation of Amines by Cytochrome P450 Enzymes

Molecular pharmacology, 1997-01, Vol.51 (1), p.147-151

1997

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Peroxidative reactions of diversozymes 1

The FASEB journal, 1996-03, Vol.10 (4), p.428-434

1996

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Peroxidative reactions of diversozymes1

The FASEB journal, 1996-03, Vol.10 (4), p.428-434

1996

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Reductive β-Scission of the Hydroperoxides of Fatty Acids and Xenobiotics: Role of Alcohol-Inducible Cytochrome P-450

Proceedings of the National Academy of Sciences - PNAS, 1990-07, Vol.87 (14), p.5499-5503

1990

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Evidence for a Role of a Perferryl-Oxygen Complex, FeO 3+ , in the N -Oxygenation of Amines by Cytochrome P450 Enzymes

Molecular pharmacology, 1997-01, Vol.51 (1), p.147-151

1997

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Adrenal proteins bound by a reactive intermediate of mitotane

Cancer chemotherapy and pharmacology, 1997, Vol.39 (6), p.537-540

1997

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Hydrocarbon Formation in the Reductive Cleavage of Hydroperoxides by Cytochrome P-450

Proceedings of the National Academy of Sciences - PNAS, 1987-03, Vol.84 (5), p.1172-1176

1987

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Drug Metabolism: Significance and Challenges

Nuclear Receptors in Drug Metabolism, 2008, p.1-41

2008

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Radical intermediates in peroxide-dependent reactions catalyzed by cytochrome P-450

Journal of biosciences, 1987-03, Vol.11 (1-4), p.35-40

1987

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Synthesis of β-3H-mitotane for use in a rapid assay for mitotane metabolism

Journal of labelled compounds & radiopharmaceuticals, 1995-02, Vol.36 (2), p.121-127

1995

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Dehydroquinase catalyzed dehydration. II. Identification of the reactive conformation of the substrate responsible for syn elimination

Journal of the American Chemical Society, 1975-10, Vol.97 (20), p.5914-5915

1975

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Radical intermediates in the catalytic cycles of cytochrome P-450

Basic life sciences, 1988, Vol.49, p.501

1988

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Multiple activated oxygen species in P450 catalysis: contributions To specificity in drug metabolism

Drug metabolism and disposition, 1998-12, Vol.26 (12), p.1190

1998

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Role of isozymes of rabbit microsomal cytochrome P-450 in the metabolism of retinoic acid, retinol, and retinal

Molecular pharmacology, 1992-02, Vol.41 (2), p.427-433

1992

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Affinity labeling of bovine opsin by trans-retinoyl chloromethane

Biochemical and biophysical research communications, 1989-04, Vol.160 (2), p.942-947

1989

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Significance of Glycine 478 in the Metabolism of N-Benzyl-1-aminobenzotriazole to Reactive Intermediates by Cytochrome P450 2B1

The use of 18 O‐exchange and base‐catalyzed N ‐dealkylation with liquid chromatography/tandem mass spectrometry to identify carbinolamide metabolites

Metabolic activation of the nontricyclic antidepressant trazodone to electrophilic quinone-imine and epoxide intermediates in human liver microsomes and recombinant P4503A4

MT FdR: a ferredoxin reductase from M. tuberculosis that couples to MT CYP51

Cytochrome P450: progress and predictions

Olefin formation in the oxidative deformylation of aldehydes by cytochrome P-450. Mechanistic implications for catalysis by oxygen-derived peroxide [Erratum to document cited in CA115(5):48632c]

Catalysis by Cytochrome P-450 of an Oxidative Reaction in Xenobiotic Aldehyde Metabolism: Deformylation with Olefin Formation

A convenient and simple method for the .alpha.'-chlorination of .alpha.,.beta. and conjugated ketones

Metabolic Activation of trans-4-Hydroxy-2-nonenal, a Toxic Product of Membrane Lipid Peroxidation and Inhibitor of P450 Cytochromes

In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent lefluonomide to its active alpha-cyanoenol metabolite A771726: mechanistic similarities with the cytochrome P450-catalyzed dehydration of aldoximes

Evidence for a Role of a Perferryl-Oxygen Complex, FeO3+, in the N-Oxygenation of Amines by Cytochrome P450 Enzymes

Peroxidative reactions of diversozymes 1

Peroxidative reactions of diversozymes1

Reductive β-Scission of the Hydroperoxides of Fatty Acids and Xenobiotics: Role of Alcohol-Inducible Cytochrome P-450

Evidence for a Role of a Perferryl-Oxygen Complex, FeO 3+ , in the N -Oxygenation of Amines by Cytochrome P450 Enzymes

Adrenal proteins bound by a reactive intermediate of mitotane

Hydrocarbon Formation in the Reductive Cleavage of Hydroperoxides by Cytochrome P-450

Drug Metabolism: Significance and Challenges

Radical intermediates in peroxide-dependent reactions catalyzed by cytochrome P-450

Synthesis of β-3H-mitotane for use in a rapid assay for mitotane metabolism

Dehydroquinase catalyzed dehydration. II. Identification of the reactive conformation of the substrate responsible for syn elimination

Radical intermediates in the catalytic cycles of cytochrome P-450

Multiple activated oxygen species in P450 catalysis: contributions To specificity in drug metabolism

Role of isozymes of rabbit microsomal cytochrome P-450 in the metabolism of retinoic acid, retinol, and retinal

Affinity labeling of bovine opsin by trans-retinoyl chloromethane

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