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Detection and clearance of RET variants in plasma cell free DNA (cfDNA) from patients (pts) treated with LOXO-292

Annals of oncology, 2018-10, Vol.29, p.viii33-viii33

2018

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Global signal peptide profiling reveals principles of selective Sec61 inhibition

Nature chemical biology, 2024-09, Vol.20 (9), p.1154-1163

2024

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Evolution of Yeast Noncoding RNAs Reveals an Alternative Mechanism for Widespread Intron Loss

Science (American Association for the Advancement of Science), 2010-11, Vol.330 (6005), p.838-841

2010

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The developmental transcriptome of Drosophila melanogaster

Nature (London), 2011-03, Vol.471 (7339), p.473-479

2011

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ETV6-NTRK3 induces aggressive acute lymphoblastic leukemia highly sensitive to selective TRK inhibition

Blood, 2018-08, Vol.132 (8), p.861-865

2018

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Evolution of alternative transcriptional circuits with identical logic

Nature, 2006-09, Vol.443 (7110), p.415-420

2006

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The development of LOXO-195, a second generation TRK kinase inhibitor that overcomes acquired resistance to 1st generation inhibitors observed in patients with TRK-fusion cancers

European journal of cancer (1990), 2016-12, Vol.69, p.S144-S145

2016

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The development of a potent, KDR/VEGFR2-sparing RET kinase inhibitor for treating patients with RET-dependent cancers

European journal of cancer (1990), 2016-12, Vol.69, p.S144-S144

2016

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Oncogenic TRK fusions are amenable to inhibition in hematologic malignancies

The Journal of clinical investigation, 2018-09, Vol.128 (9), p.3819-3825

2018

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Intercalation of a new tier of transcription regulation into an ancient circuit

Nature (London), 2010-12, Vol.468 (7326), p.959-963

2010

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Alginate microcapsule for propagation and directed differentiation of hESCs to definitive endoderm

Biomaterials, 2010-01, Vol.31 (3), p.505-514

2010

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Growth and Differentiation of Embryoid Bodies Derived from Human Embryonic Stem Cells: Effect of Glucose and Basic Fibroblast Growth Factor

Biology of reproduction, 2005-12, Vol.73 (6), p.1147-1156

2005

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Function of a genetically modified human liver cell line that stores, processes and secretes insulin

Gene therapy, 2003-03, Vol.10 (6), p.490-503

2003

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Measuring the prevalence of regional mutation rates: an analysis of silent substitutions in mammals, fungi, and insects

BMC evolutionary biology, 2008-06, Vol.8 (1), p.186, Article 186

2008

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POS0715 TREATMENT OF SLE PATIENTS WITH ZETOMIPZOMIB (KZR-616), A SELECTIVE INHIBITOR OF THE IMMUNOPROTEASOME, RESULTS IN CIRCULATING GENE EXPRESSION, PROTEIN LEVEL, AND IMMUNE CELL PHENOTYPIC CHANGES WITH POTENTIAL CORRELATIONS TO CLINICAL RESPONSE

Annals of the rheumatic diseases, 2022-06, Vol.81 (Suppl 1), p.639-640

2022

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Transmission of porcine endogenous retroviruses in severe combined immunodeficient mice xenotransplanted with fetal porcine pancreatic cells

Transplantation, 2000-10, Vol.70 (7), p.1010

2000

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Computational and experimental approaches double the number of known introns in the pathogenic yeast Candida albicans

Genome Research, 2007-04, Vol.17 (4), p.492-502

2007

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Nucleosome regulatory dynamics in response to TGFβ

Nucleic acids research, 2014-06, Vol.42 (11), p.6921

2014

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Mechanisms of arginine-induced increase in cytosolic calcium concentration in the beta-cell line NIT-1

Diabetologia, 1997-04, Vol.40 (4), p.374-382

1997

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80PTRK wild-type and fusion protein expression in solid tumors: Characterization by immunohistochemistry and in situ hybridization

Annals of oncology, 2018-09, Vol.29 (suppl_6)

2018

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Differentiation of transplanted microencapsulated fetal pancreatic cells

Transplantation, 2007-06, Vol.83 (11), p.1440-1448

2007

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Gene therapy of diabetes : glucose-stimulated insulin secretion in a human hepatoma cell line (HEP G2ins/g)

Gene therapy, 1997-11, Vol.4 (11), p.1202-1215

1997

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105PDetection and clearance of RET variants in plasma cell free DNA (cfDNA) from patients (pts) treated with LOXO-292

Annals of oncology, 2018-10, Vol.29 (suppl_8)

2018

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Effect of interleukin-10 on human anti-porcine xenogeneic cellular response in vitro

Transplantation, 2000-01, Vol.69 (1), p.112

2000

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Detection and clearance of RET variants in plasma cell free DNA (cfDNA) from patients (pts) treated with LOXO-292

Global signal peptide profiling reveals principles of selective Sec61 inhibition

Evolution of Yeast Noncoding RNAs Reveals an Alternative Mechanism for Widespread Intron Loss

The developmental transcriptome of Drosophila melanogaster

ETV6-NTRK3 induces aggressive acute lymphoblastic leukemia highly sensitive to selective TRK inhibition

Evolution of alternative transcriptional circuits with identical logic

The development of LOXO-195, a second generation TRK kinase inhibitor that overcomes acquired resistance to 1st generation inhibitors observed in patients with TRK-fusion cancers

The development of a potent, KDR/VEGFR2-sparing RET kinase inhibitor for treating patients with RET-dependent cancers

Oncogenic TRK fusions are amenable to inhibition in hematologic malignancies

Intercalation of a new tier of transcription regulation into an ancient circuit

Efficacy of Larotrectinib in TRK Fusion–Positive Cancers in Adults and Children

Alginate microcapsule for propagation and directed differentiation of hESCs to definitive endoderm

Growth and Differentiation of Embryoid Bodies Derived from Human Embryonic Stem Cells: Effect of Glucose and Basic Fibroblast Growth Factor

Function of a genetically modified human liver cell line that stores, processes and secretes insulin

Measuring the prevalence of regional mutation rates: an analysis of silent substitutions in mammals, fungi, and insects

POS0715 TREATMENT OF SLE PATIENTS WITH ZETOMIPZOMIB (KZR-616), A SELECTIVE INHIBITOR OF THE IMMUNOPROTEASOME, RESULTS IN CIRCULATING GENE EXPRESSION, PROTEIN LEVEL, AND IMMUNE CELL PHENOTYPIC CHANGES WITH POTENTIAL CORRELATIONS TO CLINICAL RESPONSE

Transmission of porcine endogenous retroviruses in severe combined immunodeficient mice xenotransplanted with fetal porcine pancreatic cells

Computational and experimental approaches double the number of known introns in the pathogenic yeast Candida albicans

Nucleosome regulatory dynamics in response to TGFβ

Mechanisms of arginine-induced increase in cytosolic calcium concentration in the beta-cell line NIT-1

80PTRK wild-type and fusion protein expression in solid tumors: Characterization by immunohistochemistry and in situ hybridization

Differentiation of transplanted microencapsulated fetal pancreatic cells

Gene therapy of diabetes : glucose-stimulated insulin secretion in a human hepatoma cell line (HEP G2ins/g)

105PDetection and clearance of RET variants in plasma cell free DNA (cfDNA) from patients (pts) treated with LOXO-292

Effect of interleukin-10 on human anti-porcine xenogeneic cellular response in vitro

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