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A Simple Mnemonic for Tautomerization Mechanisms in Organic Chemistry

Journal of chemical education, 2010-11, Vol.87 (11), p.1186-1187

Stephens, Chad E

2010

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A quantitative reverse-transcriptase PCR assay for the assessment of drug activities against intracellular Theileria annulata schizonts

International journal for parasitology -- drugs and drug resistance, 2014-12, Vol.4 (3), p.201-209

2014

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Host Cells Participate in the In Vitro Effects of Novel Diamidine Analogues against Tachyzoites of the Intracellular Apicomplexan Parasites Neospora caninum and Toxoplasma gondii

Antimicrobial Agents and Chemotherapy, 2008-06, Vol.52 (6), p.1999-2008

2008

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CYP4F enzymes are the major enzymes in human liver microsomes that catalyze the O-demethylation of the antiparasitic prodrug DB289 [2,5-bis(4-amidinophenyl)furan-bis-O-methylamidoxime]

Drug metabolism and disposition, 2006-12, Vol.34 (12), p.1985

2006

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Large, sequence-dependent effects on DNA conformation by minor groove binding compounds

Nucleic acids research, 2009-09, Vol.37 (16), p.5550

2009

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Evaluation of Arylimidamides DB1955 and DB1960 as Candidates against Visceral Leishmaniasis and Chagas' Disease: In Vivo Efficacy, Acute Toxicity, Pharmacokinetics, and Toxicology Studies

Antimicrobial Agents and Chemotherapy, 2012-07, Vol.56 (7), p.3690-3699

2012

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DNA Minor Groove Induced Dimerization of Heterocyclic Cations: Compound Structure, Binding Affinity, and Specificity for a TTAA Site

Journal of molecular biology, 2010-10, Vol.402 (5), p.847-864

2010

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The adaptive potential of a survival artist: characterization of the in vitro interactions of Toxoplasma gondii tachyzoites with di-cationic compounds in human fibroblast cell cultures

Parasitology, 2012-02, Vol.139 (2), p.208-220

2012

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Synthesis of 4 H -3-aryl-2-cyano-1,4-benzothiazine 1,1-dioxides for antiviral studies

Heterocyclic communications, 2017-04, Vol.23 (2), p.101-103

2017

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CYP1A1 and CYP1B1-Mediated Biotransformation of the Antitrypanosomal Methamidoxime Prodrug DB844 Forms Novel Metabolites Through Intramolecular Rearrangement

Journal of pharmaceutical sciences, 2014-01, Vol.103 (1), p.337-349

2014

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Aerobic epoxidation and hydroxylation of a pyrrolo[2,1- b]quinazoline under ambient conditions

Tetrahedron letters, 2010-11, Vol.51 (47), p.6129-6131

2010

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Di-cationic arylimidamides act against Neospora caninum tachyzoites by interference in membrane structure and nucleolar integrity and are active against challenge infection in mice

International journal for parasitology -- drugs and drug resistance, 2012-12, Vol.2, p.109-120

2012

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Mono- and trifluorination of the thiazole ring of 2,5-diarylthiazoles using N-fluorobenzenesulfonimide (NFSI)

Tetrahedron letters, 2013-02, Vol.54 (8), p.1025-1028

2013

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Heterocyclic Diamidine Interactions at AT Base Pairs in the DNA Minor Groove: Effects of Heterocycle Differences, DNA AT Sequence and Length

The journal of physical chemistry. B, 2008-09, Vol.112 (37), p.11809-11818

2008

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Activity of “reversed” diamidines against Trypanosoma cruzi “ in vitro”

Biochemical pharmacology, 2007-06, Vol.73 (12), p.1939-1946

2007

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Diguanidino and “Reversed” Diamidino 2,5-Diarylfurans as Antimicrobial Agents

Journal of medicinal chemistry, 2001-05, Vol.44 (11), p.1741-1748

2001

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A modified synthesis of tellurophene using NaBH4 to generate sodium telluride

Journal of organometallic chemistry, 2008-07, Vol.693 (14), p.2463-2464

2008

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Mild Normobaric Hypoxia Exposure for Human-Autonomy System Testing

Proceedings of the Human Factors and Ergonomics Society Annual Meeting, 2017-09, Vol.61 (1), p.1146-1150

2017

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Synthesis and antiparasitic evaluation of bis-2,5-[4-guanidinophenyl]thiophenes

European journal of medicinal chemistry, 2007-04, Vol.42 (4), p.552-557

2007

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Repeated Induction of Inattentional Blindness in a Simulated Aviation Environment

Proceedings of the Human Factors and Ergonomics Society Annual Meeting, 2017-09, Vol.61 (1), p.1959-1963

2017

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Synthesis, DNA Affinity, and Antiprotozoal Activity of Fused Ring Dicationic Compounds and Their Prodrugs

Journal of medicinal chemistry, 2005-08, Vol.48 (17), p.5480-5488

2005

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Phenotypic evaluation and in silico ADMET properties of novel arylimidamides in acute mouse models of Trypanosoma cruzi infection

Drug design, development and therapy, 2017-01, Vol.11, p.1095-1105

2017

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Unusual dehydroxylation of antimicrobial amidoxime prodrugs by cytochrome b5 and NADH cytochrome b5 reductase

Drug metabolism and disposition, 2005-12, Vol.33 (12), p.1886

2005

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In vitro trypanocidal activity of DB745B and other novel arylimidamides against Trypanosoma cruzi

Journal of antimicrobial chemotherapy, 2011-06, Vol.66 (6), p.1295-1297

2011

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In vitro activity and preliminary toxicity of various diamidine compounds against Trypanosoma evansi

Veterinary parasitology, 2010-05, Vol.169 (3), p.264-272

2010

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A Simple Mnemonic for Tautomerization Mechanisms in Organic Chemistry

A quantitative reverse-transcriptase PCR assay for the assessment of drug activities against intracellular Theileria annulata schizonts

Host Cells Participate in the In Vitro Effects of Novel Diamidine Analogues against Tachyzoites of the Intracellular Apicomplexan Parasites Neospora caninum and Toxoplasma gondii

CYP4F enzymes are the major enzymes in human liver microsomes that catalyze the O-demethylation of the antiparasitic prodrug DB289 [2,5-bis(4-amidinophenyl)furan-bis-O-methylamidoxime]

Large, sequence-dependent effects on DNA conformation by minor groove binding compounds

Evaluation of Arylimidamides DB1955 and DB1960 as Candidates against Visceral Leishmaniasis and Chagas' Disease: In Vivo Efficacy, Acute Toxicity, Pharmacokinetics, and Toxicology Studies

DNA Minor Groove Induced Dimerization of Heterocyclic Cations: Compound Structure, Binding Affinity, and Specificity for a TTAA Site

The adaptive potential of a survival artist: characterization of the in vitro interactions of Toxoplasma gondii tachyzoites with di-cationic compounds in human fibroblast cell cultures

Synthesis of 4 H -3-aryl-2-cyano-1,4-benzothiazine 1,1-dioxides for antiviral studies

CYP1A1 and CYP1B1-Mediated Biotransformation of the Antitrypanosomal Methamidoxime Prodrug DB844 Forms Novel Metabolites Through Intramolecular Rearrangement

Aerobic epoxidation and hydroxylation of a pyrrolo[2,1- b]quinazoline under ambient conditions

Di-cationic arylimidamides act against Neospora caninum tachyzoites by interference in membrane structure and nucleolar integrity and are active against challenge infection in mice

Mono- and trifluorination of the thiazole ring of 2,5-diarylthiazoles using N-fluorobenzenesulfonimide (NFSI)

Heterocyclic Diamidine Interactions at AT Base Pairs in the DNA Minor Groove: Effects of Heterocycle Differences, DNA AT Sequence and Length

Activity of “reversed” diamidines against Trypanosoma cruzi “ in vitro”

Diguanidino and “Reversed” Diamidino 2,5-Diarylfurans as Antimicrobial Agents

A modified synthesis of tellurophene using NaBH4 to generate sodium telluride

Mild Normobaric Hypoxia Exposure for Human-Autonomy System Testing

Synthesis and antiparasitic evaluation of bis-2,5-[4-guanidinophenyl]thiophenes

Repeated Induction of Inattentional Blindness in a Simulated Aviation Environment

Synthesis, DNA Affinity, and Antiprotozoal Activity of Fused Ring Dicationic Compounds and Their Prodrugs

Phenotypic evaluation and in silico ADMET properties of novel arylimidamides in acute mouse models of Trypanosoma cruzi infection

Unusual dehydroxylation of antimicrobial amidoxime prodrugs by cytochrome b5 and NADH cytochrome b5 reductase

In vitro trypanocidal activity of DB745B and other novel arylimidamides against Trypanosoma cruzi

In vitro activity and preliminary toxicity of various diamidine compounds against Trypanosoma evansi

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