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Feedback control methods for drug dosage optimisation. Concepts, classification and clinical application

Clinical pharmacokinetics, 1985-01, Vol.10 (6), p.457-476

1985

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New strategies in drug development and clinical evaluation : the population approach : commentary on an action for co-operative research

European journal of clinical pharmacology, 1993-09, Vol.45 (2), p.93-94

1993

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A mathematical model of the kinetics of 5-fluorouracil and its metabolites in cancer patients

Cancer chemotherapy and pharmacology, 1991-01, Vol.28 (2), p.123-129

1991

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A mathematical model for dynamics of cardiovascular drug action : application to intravenous dihydropyridines in healthy volunteers

Journal of pharmacokinetics and biopharmaceutics, 1993-10, Vol.21 (5), p.489-514

1993

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L’architecture religieuse en Allemagne entre 1220 et 1350

Bulletin monumental, 2010, Vol.168 (3), p.227-242

Schurr, Marc Carel

2010

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Recherches récentes sur le gothique tardif (1350-1550)

Bulletin monumental, 2010, Vol.168 (3), p.243-280

Nußbaum, Norbert

2010

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Pharmacokinetic aspects of the sublingual administration of vincamine

Biopharmaceutics & drug disposition, 1990-05, Vol.11 (4), p.279-309

1990

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Hyperparameter Estimation Using Stochastic Approximation with Application to Population Pharmacokinetics

Biometrics, 1988-09, Vol.44 (3), p.673-683

1988

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A semimechanistic and mechanistic population PK–PD model for biomarker response to ibandronate, a new bisphosphonate for the treatment of osteoporosis

British journal of clinical pharmacology, 2004-12, Vol.58 (6), p.618-631

2004

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Modelling and simulation in the development and use of anti-cancer agents : An underused tool?

Journal of pharmacokinetics and pharmacodynamics, 2004-12, Vol.31 (6), p.419-440

2004

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Population pharmacokinetics and concentration–effect relationships of capecitabine metabolites in colorectal cancer patients

British journal of clinical pharmacology, 2003-03, Vol.55 (3), p.252-263

2003

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Nonparametric maximum likelihood estimation for population pharmacokinetics, with application to cyclosporine

Journal of pharmacokinetics and biopharmaceutics, 1988-06, Vol.16 (3), p.311-327

1988

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La méthode de la clairance rénale pour l'individualisation des posologies du lithium en routine hospitalière

Encéphale, 1984, Vol.10 (5), p.223-230

1984

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Effect of adrenalectomy and aldosterone on the modulation of mineralocorticoid receptors in rat kidney

The Journal of biological chemistry, 1981-01, Vol.256 (1), p.142-147

1981

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Physiologically based pharmacokinetic study on a cyclosporin derivative, SDZ IMM 125

Journal of pharmacokinetics and biopharmaceutics, 1994-10, Vol.22 (5), p.327-365

1994

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Cytoplasmic and nuclear uptake of aldosterone in toad bladder: a mathematical modeling approach

American Journal of Physiology: Cell Physiology, 1985-01, Vol.248 (1), p.C88-C101

1985

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Non-linear mixed effects modeling : From methodology and software development to driving implementation in drug development science

Journal of pharmacokinetics and pharmacodynamics, 2005-04, Vol.32 (2), p.161-183

2005

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Alternative Approaches to Estimation of Population Pharmacokinetic Parameters: Comparison with the Nonlinear Mixed-Effect Model

Drug metabolism reviews, 1984, Vol.15 (1-2), p.265-292

1984

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A mathematical model of the kinetics of 5-fluorouracil and its catabolites in freshly isolated rat hepatocytes

Biochemical pharmacology, 1984-09, Vol.33 (17), p.2727-2732

1984

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Description of the time course of the prolactin suppressant effect of the dopamine agonist CQP201‐403 by an integrated pharmacokinetic‐ pharmacodynamic model

British journal of clinical pharmacology, 1986-07, Vol.22 (1), p.1-13

1986

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Sparse-Sampling Optimal Designs in Pharmacokinetics and Toxicokinetics

Drug information journal, 1995, Vol.29 (3), p.997-1019

1995

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Application of Sparse Sampling Approaches in Rodent Toxicokinetics: A Prospective View

Drug information journal, 1994, Vol.28 (1), p.263-279

1994

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Clinical pharmacokinetic/pharmacodynamic and physiologically based pharmacokinetic modeling in new drug development: the capecitabine experience

Investigational new drugs, 2003-05, Vol.21 (2), p.195-223

2003

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On the dose dependency of cyclosporin A absorption and disposition in healthy volunteers

Journal of pharmacokinetics and biopharmaceutics, 1988-08, Vol.16 (4), p.331-353

1988

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Isoniazid plasma and lymph kinetics after intravenous injection in dogs

Arzneimittel-Forschung, 1984, Vol.34 (10), p.1283

1984

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Feedback control methods for drug dosage optimisation. Concepts, classification and clinical application

New strategies in drug development and clinical evaluation : the population approach : commentary on an action for co-operative research

A mathematical model of the kinetics of 5-fluorouracil and its metabolites in cancer patients

A mathematical model for dynamics of cardiovascular drug action : application to intravenous dihydropyridines in healthy volunteers

L’architecture religieuse en Allemagne entre 1220 et 1350

Recherches récentes sur le gothique tardif (1350-1550)

Pharmacokinetic aspects of the sublingual administration of vincamine

Hyperparameter Estimation Using Stochastic Approximation with Application to Population Pharmacokinetics

A semimechanistic and mechanistic population PK–PD model for biomarker response to ibandronate, a new bisphosphonate for the treatment of osteoporosis

Modelling and simulation in the development and use of anti-cancer agents : An underused tool?

Population pharmacokinetics and concentration–effect relationships of capecitabine metabolites in colorectal cancer patients

Nonparametric maximum likelihood estimation for population pharmacokinetics, with application to cyclosporine

La méthode de la clairance rénale pour l'individualisation des posologies du lithium en routine hospitalière

Effect of adrenalectomy and aldosterone on the modulation of mineralocorticoid receptors in rat kidney

Physiologically based pharmacokinetic study on a cyclosporin derivative, SDZ IMM 125

Cytoplasmic and nuclear uptake of aldosterone in toad bladder: a mathematical modeling approach

Non-linear mixed effects modeling : From methodology and software development to driving implementation in drug development science

Alternative Approaches to Estimation of Population Pharmacokinetic Parameters: Comparison with the Nonlinear Mixed-Effect Model

A mathematical model of the kinetics of 5-fluorouracil and its catabolites in freshly isolated rat hepatocytes

Description of the time course of the prolactin suppressant effect of the dopamine agonist CQP201‐403 by an integrated pharmacokinetic‐ pharmacodynamic model

Sparse-Sampling Optimal Designs in Pharmacokinetics and Toxicokinetics

Application of Sparse Sampling Approaches in Rodent Toxicokinetics: A Prospective View

Clinical pharmacokinetic/pharmacodynamic and physiologically based pharmacokinetic modeling in new drug development: the capecitabine experience

On the dose dependency of cyclosporin A absorption and disposition in healthy volunteers

Isoniazid plasma and lymph kinetics after intravenous injection in dogs

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