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Applying a high-throughput fluorescence polarization assay for the discovery of chemical probes blocking La:RNA interactions in vitro and in cells

PloS one, 2017-03, Vol.12 (3), p.e0173246-e0173246

2017

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Pim protein kinases regulate energy metabolism and cell growth

Proceedings of the National Academy of Sciences - PNAS, 2011-01, Vol.108 (2), p.528-533

2011

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Opaganib Downregulates N-Myc Expression and Suppresses In Vitro and In Vivo Growth of Neuroblastoma Cells

Cancers, 2024-05, Vol.16 (9), p.1779

2024

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Sphingosine kinase-2 maintains viral latency and survival for KSHV-infected endothelial cells

PloS one, 2014-07, Vol.9 (7), p.e102314-e102314

2014

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Inhibition of sphingosine kinase-2 suppresses inflammation and attenuates graft injury after liver transplantation in rats

PloS one, 2012-07, Vol.7 (7), p.e41834

2012

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Discovery and evaluation of inhibitors of human ceramidase

Molecular cancer therapeutics, 2011-11, Vol.10 (11), p.2052-2061

2011

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Modeling the Association between 43 Different Clinical and Pathological Variables and the Severity of Cognitive Impairment in a Large Autopsy Cohort of Elderly Persons

Brain pathology (Zurich, Switzerland), 2010-01, Vol.20 (1), p.66-79

2010

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White Matter Hyperintensity Associations with Cerebral Blood Flow in Elderly Subjects Stratified by Cerebrovascular Risk

Journal of stroke and cerebrovascular diseases, 2017-04, Vol.26 (4), p.779-786

2017

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Combining Nanoliposomal Ceramide with Sorafenib Synergistically Inhibits Melanoma and Breast Cancer Cell Survival to Decrease Tumor Development

Clinical cancer research, 2008-06, Vol.14 (11), p.3571-3581

2008

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Preconditioning Stimuli Induce Autophagy via Sphingosine Kinase 2 in Mouse Cortical Neurons

The Journal of biological chemistry, 2014-07, Vol.289 (30), p.20845-20857

2014

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Tolyporphin Macrocycles from the Cyanobacterium Tolypothrix nodosa Selectively Bind Copper and Silver and Reverse Multidrug Resistance

Inorganic chemistry, 2017-05, Vol.56 (10), p.5577-5585

2017

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Antitumor effect of the novel sphingosine kinase 2 inhibitor ABC294640 is enhanced by inhibition of autophagy and by sorafenib in human cholangiocarcinoma cells

Oncotarget, 2016-04, Vol.7 (15), p.20080-20092

2016

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Diffuse optical assessment of cerebral‐autoregulation in older adults stratified by cerebrovascular risk

Journal of biophotonics, 2020-10, Vol.13 (10), p.e202000073-n/a

2020

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Sorafenib sensitizes solid tumors to Apo2L/TRAIL and Apo2L/TRAIL receptor agonist antibodies by the Jak2-Stat3-Mcl1 axis

PloS one, 2013-09, Vol.8 (9), p.e75414

2013

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Suppression of Ulcerative Colitis in Mice by Orally Available Inhibitors of Sphingosine Kinase

Digestive diseases and sciences, 2008-04, Vol.53 (4), p.997-1012

2008

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Reduction of TRAIL-Induced Mcl-1 and cIAP2 by c-Myc or Sorafenib Sensitizes Resistant Human Cancer Cells to TRAIL-Induced Death

Cancer cell, 2007-07, Vol.12 (1), p.66-80

2007

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Combined anticancer effects of sphingosine kinase inhibitors and sorafenib

Investigational new drugs, 2011-12, Vol.29 (6), p.1132-1142

2011

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Targeting sphingosine kinase induces apoptosis and tumor regression for KSHV-associated primary effusion lymphoma

Molecular cancer therapeutics, 2014-01, Vol.13 (1), p.154-164

2014

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PIM1 Protein Kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells

Cancer biology & therapy, 2009-05, Vol.8 (9), p.846-853

2009

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Sugihara causality analysis of scalp EEG for detection of early Alzheimer's disease

NeuroImage clinical, 2015-01, Vol.7 (C), p.258-265

2015

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Sphingosine kinase-2 inhibition improves mitochondrial function and survival after hepatic ischemia–reperfusion

Journal of hepatology, 2012-01, Vol.56 (1), p.137-145

2012

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Novel benzylidene-thiazolidine-2,4-diones inhibit Pim protein kinase activity and induce cell cycle arrest in leukemia and prostate cancer cells

Molecular cancer therapeutics, 2009-06, Vol.8 (6), p.1473-1483

2009

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Association between male gender and cortical Lewy body pathology in large autopsy series

Journal of neurology, 2010-11, Vol.257 (11), p.1875-1881

2010

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Preclinical AD Workgroup staging: pathological correlates and potential challenges

Neurobiology of aging, 2012-03, Vol.33 (3), p.622.e1-622.e16

2012

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Development, validation and application of a new fornix template for studies of aging and preclinical Alzheimer's disease

NeuroImage clinical, 2017-01, Vol.13 (C), p.106-115

2017

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Applying a high-throughput fluorescence polarization assay for the discovery of chemical probes blocking La:RNA interactions in vitro and in cells

Pim protein kinases regulate energy metabolism and cell growth

Opaganib Downregulates N-Myc Expression and Suppresses In Vitro and In Vivo Growth of Neuroblastoma Cells

Sphingosine kinase-2 maintains viral latency and survival for KSHV-infected endothelial cells

Inhibition of sphingosine kinase-2 suppresses inflammation and attenuates graft injury after liver transplantation in rats

Discovery and evaluation of inhibitors of human ceramidase

Modeling the Association between 43 Different Clinical and Pathological Variables and the Severity of Cognitive Impairment in a Large Autopsy Cohort of Elderly Persons

White Matter Hyperintensity Associations with Cerebral Blood Flow in Elderly Subjects Stratified by Cerebrovascular Risk

Combining Nanoliposomal Ceramide with Sorafenib Synergistically Inhibits Melanoma and Breast Cancer Cell Survival to Decrease Tumor Development

Preconditioning Stimuli Induce Autophagy via Sphingosine Kinase 2 in Mouse Cortical Neurons

Tolyporphin Macrocycles from the Cyanobacterium Tolypothrix nodosa Selectively Bind Copper and Silver and Reverse Multidrug Resistance

Antitumor effect of the novel sphingosine kinase 2 inhibitor ABC294640 is enhanced by inhibition of autophagy and by sorafenib in human cholangiocarcinoma cells

Diffuse optical assessment of cerebral‐autoregulation in older adults stratified by cerebrovascular risk

Sorafenib sensitizes solid tumors to Apo2L/TRAIL and Apo2L/TRAIL receptor agonist antibodies by the Jak2-Stat3-Mcl1 axis

Suppression of Ulcerative Colitis in Mice by Orally Available Inhibitors of Sphingosine Kinase

Reduction of TRAIL-Induced Mcl-1 and cIAP2 by c-Myc or Sorafenib Sensitizes Resistant Human Cancer Cells to TRAIL-Induced Death

Combined anticancer effects of sphingosine kinase inhibitors and sorafenib

Targeting sphingosine kinase induces apoptosis and tumor regression for KSHV-associated primary effusion lymphoma

PIM1 Protein Kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells

Sugihara causality analysis of scalp EEG for detection of early Alzheimer's disease

Sphingosine kinase-2 inhibition improves mitochondrial function and survival after hepatic ischemia–reperfusion

Novel benzylidene-thiazolidine-2,4-diones inhibit Pim protein kinase activity and induce cell cycle arrest in leukemia and prostate cancer cells

Association between male gender and cortical Lewy body pathology in large autopsy series

Preclinical AD Workgroup staging: pathological correlates and potential challenges

Development, validation and application of a new fornix template for studies of aging and preclinical Alzheimer's disease

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