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Three- and four-dimensional-quantitative structure activity relationship (3D/4D-QSAR) analyses of CYP2C9 inhibitors

Drug metabolism and disposition, 2000-08, Vol.28 (8), p.994

2000

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Present and future in vitro approaches for drug metabolism

Journal of pharmacological and toxicological methods, 2000-07, Vol.44 (1), p.313-324

2000

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Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine

The Journal of pharmacology and experimental therapeutics, 1996-02, Vol.276 (2), p.658

1996

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In vitro interaction of the antipsychotic agent olanzapine with human cytochromes P450 CYP2C9, CYP2C19, CYP2D6 and CYP3A

British journal of clinical pharmacology, 1996-03, Vol.41 (3), p.181-186

1996

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In Vitro Methods for Assessing Human Hepatic Drug Metabolism: Their use in Drug Development

Drug metabolism reviews, 1993, Vol.25 (4), p.453-484

1993

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Disposition and metabolism of semagacestat, a {gamma}-secretase inhibitor, in humans

Drug metabolism and disposition, 2010-04, Vol.38 (4), p.554

2010

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Effects of single-dose and fractionated cranial irradiation on rat brain accumulation of methotrexate

Cancer research (Chicago, Ill.), 1984-11, Vol.44 (11), p.5092-5094

1984

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PREDICTING DRUG INTERACTIONS AND PHARMACOKINETIC VARIABILITY WITH IN VITRO METHODS: THE OLANZAPINE EXPERIENCE1

Drug metabolism reviews, 1999, Vol.31 (1), p.15-28

1999

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PREDICTING DRUG INTERACTIONS AND PHARMACOKINETIC VARIABILITY WITH IN VITRO METHODS: THE OLANZAPINE EXPERIENCE

Drug metabolism reviews, 1999-01, Vol.31 (1), p.15-28

1999

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A population approach to enzyme characterization and identification : Application to phenacetin O-deethylation

Pharmaceutical research, 2000-12, Vol.17 (12), p.1531-1536

2000

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Three and four dimensional-quantitative structure activity relationship (3D/4D-QSAR) analyses of CYP2D6 inhibitors

Pharmacogenetics (London), 1999-08, Vol.9 (4), p.477

1999

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The human drug metabolizing cytochromes P450

Journal of pharmacokinetics and biopharmaceutics, 1996-10, Vol.24 (5), p.461-473

1996

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Human cytochrome P450 3A (CYP3A) mediated midazolam metabolism: the effect of assay conditions and regioselective stimulation by alpha-naphthoflavone, terfenadine and testosterone

Pharmacogenetics (London), 1998-04, Vol.8 (2), p.137

1998

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The effect of diet and litter size on the elimination of 2,4,5,2′,4′,5′-[ 14C]hexachlorobiphenyl from lactating mice

Toxicology and applied pharmacology, 1990-06, Vol.104 (1), p.9-16

1990

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The influence of time of maternal exposure to 2,4,5,2′,4′,5′-hexachlorobiphenyl on its accumulation in their nursing offspring

Toxicology and applied pharmacology, 1990-06, Vol.104 (1), p.1-8

1990

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Examination of purported probes of human CYP2B6

Pharmacogenetics (London), 1997-06, Vol.7 (3), p.165-179

1997

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Organ function and drug pharmacology after total body irradiation plus bone marrow transplantation

International journal of radiation oncology, biology, physics, 1989, Vol.17, p.192-193

1989

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Transfer of 2,4,5,2′,4′,5′-hexachlorobiphenyl across the in situ perfused guinea pig placenta

Toxicology and applied pharmacology, 1988-10, Vol.96 (1), p.7-13

1988

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Interaction of human liver cytochromes P450 in vitro with LY307640, a gastric proton pump inhibitor

Pharmacogenetics (London), 1996-02, Vol.6 (1), p.81-91

1996

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Chronic effects of fractionated renal irradiation on the pharmacokinetics of intravenous methotrexate

International journal of radiation oncology, biology, physics, 1987-05, Vol.13 (5), p.759-764

1987

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Influence of lipolysis on the mobilization of 2,4,5,2'4',5'-hexachlorobiphenyl from adipocytes in vitro

Journal of toxicology and environmental health, 1987, Vol.20 (1-2), p.163-171

1987

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Effect of asparaginase on cell membranes of sensitive and resistants mouse lymphoma cells

In Vitro, 1984-05, Vol.20 (5), p.376-384

1984

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Influence of lipolysis on the mobilization of 2,4,5,2′4′,5′-hexachlorobiphenyl from adipocytes in vitro

Journal of toxicology and environmental health, 1987-01, Vol.20 (1-2), p.163-171

1987

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Human cytochrome P450 3A (CYP3A) mediated midazolam metabolism: the effect of assay conditions and regioselective stimulation by ??-naphthoflavone, terfenadine and testosterone

Pharmacogenetics (London), 1998-04, Vol.8 (2), p.137-156

1998

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Effect of hepatic irradiation on the toxicity and pharmacokinetics of adriamycin in children

International journal of radiation oncology, biology, physics, 1981-07, Vol.7 (7), p.953-956

1981

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Three- and four-dimensional-quantitative structure activity relationship (3D/4D-QSAR) analyses of CYP2C9 inhibitors

Present and future in vitro approaches for drug metabolism

Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine

In vitro interaction of the antipsychotic agent olanzapine with human cytochromes P450 CYP2C9, CYP2C19, CYP2D6 and CYP3A

In Vitro Methods for Assessing Human Hepatic Drug Metabolism: Their use in Drug Development

Disposition and metabolism of semagacestat, a {gamma}-secretase inhibitor, in humans

Effects of single-dose and fractionated cranial irradiation on rat brain accumulation of methotrexate

PREDICTING DRUG INTERACTIONS AND PHARMACOKINETIC VARIABILITY WITH IN VITRO METHODS: THE OLANZAPINE EXPERIENCE1

PREDICTING DRUG INTERACTIONS AND PHARMACOKINETIC VARIABILITY WITH IN VITRO METHODS: THE OLANZAPINE EXPERIENCE

A population approach to enzyme characterization and identification : Application to phenacetin O-deethylation

Three and four dimensional-quantitative structure activity relationship (3D/4D-QSAR) analyses of CYP2D6 inhibitors

The human drug metabolizing cytochromes P450

Human cytochrome P450 3A (CYP3A) mediated midazolam metabolism: the effect of assay conditions and regioselective stimulation by alpha-naphthoflavone, terfenadine and testosterone

The effect of diet and litter size on the elimination of 2,4,5,2′,4′,5′-[ 14C]hexachlorobiphenyl from lactating mice

The influence of time of maternal exposure to 2,4,5,2′,4′,5′-hexachlorobiphenyl on its accumulation in their nursing offspring

Examination of purported probes of human CYP2B6

Organ function and drug pharmacology after total body irradiation plus bone marrow transplantation

Transfer of 2,4,5,2′,4′,5′-hexachlorobiphenyl across the in situ perfused guinea pig placenta

Interaction of human liver cytochromes P450 in vitro with LY307640, a gastric proton pump inhibitor

Chronic effects of fractionated renal irradiation on the pharmacokinetics of intravenous methotrexate

Influence of lipolysis on the mobilization of 2,4,5,2'4',5'-hexachlorobiphenyl from adipocytes in vitro

Effect of asparaginase on cell membranes of sensitive and resistants mouse lymphoma cells

Influence of lipolysis on the mobilization of 2,4,5,2′4′,5′-hexachlorobiphenyl from adipocytes in vitro

Human cytochrome P450 3A (CYP3A) mediated midazolam metabolism: the effect of assay conditions and regioselective stimulation by ??-naphthoflavone, terfenadine and testosterone

Effect of hepatic irradiation on the toxicity and pharmacokinetics of adriamycin in children

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