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Effect of the vascular endothelial growth factor receptor‐2 antibody DC101 plus gemcitabine on growth, metastasis and angiogenesis of human pancreatic cancer growing orthotopically in nude mice

International journal of cancer, 2002-11, Vol.102 (2), p.101-108

2002

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Antibody‐mediated neutralization of autocrine Gas6 inhibits the growth of pancreatic ductal adenocarcinoma tumors in vivo

International journal of cancer, 2016-09, Vol.139 (6), p.1340-1349

2016

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IGF-1 receptor contributes to the malignant phenotype in human and canine osteosarcoma

Journal of cellular biochemistry, 2004-05, Vol.92 (1), p.77-91

2004

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Efficacy of ganitumab (AMG 479), alone and in combination with rapamycin, in Ewing's and osteogenic sarcoma models

The Journal of pharmacology and experimental therapeutics, 2011-06, Vol.337 (3), p.644

2011

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Preclinical Evaluation of AMG 900, a Novel Potent and Highly Selective Pan-Aurora Kinase Inhibitor with Activity in Taxane-Resistant Tumor Cell Lines

Cancer research (Chicago, Ill.), 2010-12, Vol.70 (23), p.9846-9854

2010

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Orthotopic models are necessary to predict therapy of transplantable tumors in mice

Cancer and metastasis reviews, 1998, Vol.17 (3), p.279-284

1998

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Tumor penetration and epidermal growth factor receptor saturation by panitumumab correlate with antitumor activity in a preclinical model of human cancer

Molecular cancer, 2012-07, Vol.11 (1), p.47-47, Article 47

2012

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Treatment of Human Metastatic Transitional Cell Carcinoma of the Bladder in a Murine Model with the Anti-Vascular Endothelial Growth Factor Receptor Monoclonal Antibody DC101 and Paclitaxel

Clinical cancer research, 2000-07, Vol.6 (7), p.2635-2643

2000

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Augmentation of Radiation Response by Panitumumab in Models of Upper Aerodigestive Tract Cancer

International journal of radiation oncology, biology, physics, 2008-10, Vol.72 (2), p.534-542

2008

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Association of K- ras Mutational Status and Clinical Outcomes in Patients with Metastatic Colorectal Cancer Receiving Panitumumab Alone

Clinical colorectal cancer, 2008-05, Vol.7 (3), p.184-190

2008

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Discovery and evaluation of dual CDK1 and CDK2 inhibitors

Cancer research (Chicago, Ill.), 2006-04, Vol.66 (8), p.4299-4308

2006

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Interleukin 8 expression regulates tumorigenicity and metastasis in human bladder cancer

Cancer research (Chicago, Ill.), 2000-04, Vol.60 (8), p.2290-2299

2000

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Activity of panitumumab alone or with chemotherapy in non-small cell lung carcinoma cell lines expressing mutant epidermal growth factor receptor

Molecular cancer therapeutics, 2009-06, Vol.8 (6), p.1536-1546

2009

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Anti-tumor activity of motesanib in a medullary thyroid cancer model

Journal of endocrinological investigation, 2012-02, Vol.35 (2), p.181-190

2012

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IGF1R blockade with ganitumab results in systemic effects on the GH–IGF axis in mice

Journal of endocrinology, 2014-04, Vol.221 (1), p.145-155

2014

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Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells

Clinical cancer research, 1995-01, Vol.1 (1), p.19-31

1995

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Cortical NOS inhibition raises the lower limit of cerebral blood flow-arterial pressure autoregulation

American journal of physiology. Heart and circulatory physiology, 1999-04, Vol.276 (4), p.H1253-H1262

1999

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Variability in the magnitude of the cerebral blood flow response and the shape of the cerebral blood flow: Pressure autoregulation curve during hypotension in normal rats

Anesthesiology (Philadelphia), 2002-08, Vol.97 (2), p.488-496

2002

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Abstract 2587: A novel covalent inhibitor of mutant but not wild-type (WT) epidermal growth factor receptor (EGFR) has activity in vitro and in vivo in non-small cell lung cancer (NSCLC) models

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.2587-2587

2015

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Gene Expression Profiles Can Predict Panitumumab Monotherapy Responsiveness in Human Tumor Xenograft Models1

Neoplasia (New York, N.Y.), 2013-02, Vol.15 (2), p.125-132

2013

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Mechanisms mediating the negative interaction between oxaliplatin (Ox) and epidermal growth factor receptor (EGFR) inhibitors in patients (pts) with KRAS mutant (MT) colorectal cancer (CRC)

Journal of clinical oncology, 2012-05, Vol.30 (15_suppl), p.3580-3580

2012

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Down-regulation of c-Met inhibits growth in the liver of human colorectal carcinoma cells

Cancer research (Chicago, Ill.), 2003-06, Vol.63 (11), p.2990-2996

2003

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Expression of interleukin 8 correlates with the metastatic potential of human melanoma cells in nude mice

Cancer research (Chicago, Ill.), 1994-06, Vol.54 (12), p.3242-3247

1994

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Abstract 728: AMG 337, a novel, potent and selective MET kinase inhibitor, has robust growth inhibitory activity in MET-dependent cancer models

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.728-728

2014

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Effect of the vascular endothelial growth factor receptor‐2 antibody DC101 plus gemcitabine on growth, metastasis and angiogenesis of human pancreatic cancer growing orthotopically in nude mice

Antibody‐mediated neutralization of autocrine Gas6 inhibits the growth of pancreatic ductal adenocarcinoma tumors in vivo

IGF-1 receptor contributes to the malignant phenotype in human and canine osteosarcoma

Efficacy of ganitumab (AMG 479), alone and in combination with rapamycin, in Ewing's and osteogenic sarcoma models

Preclinical Evaluation of AMG 900, a Novel Potent and Highly Selective Pan-Aurora Kinase Inhibitor with Activity in Taxane-Resistant Tumor Cell Lines

Orthotopic models are necessary to predict therapy of transplantable tumors in mice

Tumor penetration and epidermal growth factor receptor saturation by panitumumab correlate with antitumor activity in a preclinical model of human cancer

Discovery of N‑(4-(3-(2-Aminopyrimidin-4-yl)pyridin-2-yloxy)phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine (AMG 900), A Highly Selective, Orally Bioavailable Inhibitor of Aurora Kinases with Activity against Multidrug-Resistant Cancer Cell Lines

Treatment of Human Metastatic Transitional Cell Carcinoma of the Bladder in a Murine Model with the Anti-Vascular Endothelial Growth Factor Receptor Monoclonal Antibody DC101 and Paclitaxel

Augmentation of Radiation Response by Panitumumab in Models of Upper Aerodigestive Tract Cancer

Association of K- ras Mutational Status and Clinical Outcomes in Patients with Metastatic Colorectal Cancer Receiving Panitumumab Alone

Discovery and evaluation of dual CDK1 and CDK2 inhibitors

Interleukin 8 expression regulates tumorigenicity and metastasis in human bladder cancer

Activity of panitumumab alone or with chemotherapy in non-small cell lung carcinoma cell lines expressing mutant epidermal growth factor receptor

Anti-tumor activity of motesanib in a medullary thyroid cancer model

IGF1R blockade with ganitumab results in systemic effects on the GH–IGF axis in mice

Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells

Cortical NOS inhibition raises the lower limit of cerebral blood flow-arterial pressure autoregulation

Variability in the magnitude of the cerebral blood flow response and the shape of the cerebral blood flow: Pressure autoregulation curve during hypotension in normal rats

Abstract 2587: A novel covalent inhibitor of mutant but not wild-type (WT) epidermal growth factor receptor (EGFR) has activity in vitro and in vivo in non-small cell lung cancer (NSCLC) models

Gene Expression Profiles Can Predict Panitumumab Monotherapy Responsiveness in Human Tumor Xenograft Models1

Mechanisms mediating the negative interaction between oxaliplatin (Ox) and epidermal growth factor receptor (EGFR) inhibitors in patients (pts) with KRAS mutant (MT) colorectal cancer (CRC)

Down-regulation of c-Met inhibits growth in the liver of human colorectal carcinoma cells

Expression of interleukin 8 correlates with the metastatic potential of human melanoma cells in nude mice

Abstract 728: AMG 337, a novel, potent and selective MET kinase inhibitor, has robust growth inhibitory activity in MET-dependent cancer models

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