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Structure- and Property-Based Optimization of Efficient Pan-Bromodomain and Extra Terminal Inhibitors to Identify Oral and Intravenous Candidate I‑BET787

Journal of medicinal chemistry, 2024-06, Vol.67 (12), p.10464-10489

2024

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Discovery of GSK251: A Highly Potent, Highly Selective, Orally Bioavailable Inhibitor of PI3Kδ with a Novel Binding Mode

Journal of medicinal chemistry, 2021-09, Vol.64 (18), p.13780-13792

2021

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Acetylation of the Catalytic Lysine Inhibits Kinase Activity in PI3Kδ

ACS chemical biology, 2021-09, Vol.16 (9), p.1644-1653

2021

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Durability performance of alkali-activated concrete with pre-treated coarse recycled aggregates for pavements

Scientific reports, 2024-06, Vol.14 (1), p.13776-16

2024

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Diffusion tensor imaging of forearm nerves in humans

Journal of magnetic resonance imaging, 2012-10, Vol.36 (4), p.920-927

2012

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Mr-derived cerebral spinal fluid hydrodynamics as a marker and a risk factor for intracranial hypertension in astronauts exposed to microgravity

Journal of magnetic resonance imaging, 2015-12, Vol.42 (6), p.1560-1571

2015

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Water T2 as an early, global and practical biomarker for metabolic syndrome: an observational cross-sectional study

Journal of translational medicine, 2017-12, Vol.15 (1), p.258-258, Article 258

2017

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Efficient methods for enol phosphate synthesis using carbon-centred magnesium bases

Organic & biomolecular chemistry, 2015-10, Vol.13 (40), p.10131-10135

2015

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WHOLE BLOOD T2P LINKS HEMOGLOBIN STATUS TO CARDIOMETABOLIC HEALTH

American journal of preventive cardiology, 2023-09, Vol.15, p.100576, Article 100576

2023

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Simulation of Wood Polymer Composites with Finite Element Analysis

Polymers, 2023-04, Vol.15 (9), p.1977

2023

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Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2)

Journal of medicinal chemistry, 2016-12, Vol.59 (23), p.10738-10749

2016

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Development of Biodegradable Composites Using Polycaprolactone and Bamboo Powder

Polymers, 2022-10, Vol.14 (19), p.4169

2022

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High strength thin-walled rectangular concrete-filled steel tubular slender beam-columns, Part II: Behavior

Journal of constructional steel research, 2012-03, Vol.70, p.368-376

2012

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Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X‑ray Fragment Screening

Journal of medicinal chemistry, 2016-06, Vol.59 (11), p.5356-5367

2016

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Single-Step Microwave-Mediated Synthesis of Oxazoles and Thiazoles from 3-Oxetanone: A Synthetic and Computational Study

Chemistry : a European journal, 2013-07, Vol.19 (29), p.9655-9662

2013

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Flexural Behavior of Precast Rectangular Reinforced Concrete Beams with Intermediate Connection Filled with High-Performance Concrete

Buildings (Basel), 2024-09, Vol.14 (9), p.2823

2024

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Aptamer-based search for correlates of plasma and serum water T2: implications for early metabolic dysregulation and metabolic syndrome

Biomarker research, 2018-09, Vol.6 (1), p.28-28, Article 28

2018

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Artificial neural network model for strength predictions of CFST columns strengthened with CFRP

Engineering structures, 2023-04, Vol.281, p.115784, Article 115784

2023

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Discovery of GSK143, a highly potent, selective and orally efficacious spleen tyrosine kinase inhibitor

Bioorganic & medicinal chemistry letters, 2011-10, Vol.21 (20), p.6188-6194

2011

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p38α Mitogen-Activated Protein Kinase Inhibitors: Optimization of a Series of Biphenylamides to Give a Molecule Suitable for Clinical Progression

Journal of medicinal chemistry, 2009-10, Vol.52 (20), p.6257-6269

2009

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A practical drug discovery project at the undergraduate level

Drug discovery today, 2013-12, Vol.18 (23-24), p.1158-1172

2013

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Investigation of a Bicyclo[1.1.1]pentane as a Phenyl Replacement within an LpPLA 2 Inhibitor

ACS medicinal chemistry letters, 2017-01, Vol.8 (1), p.43-48

2017

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Numerical analysis of axially loaded circular high strength concrete-filled double steel tubular short columns

Thin-walled structures, 2019-05, Vol.138, p.105-116

2019

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A Photoaffinity‐Based Fragment‐Screening Platform for Efficient Identification of Protein Ligands

Angewandte Chemie, 2020-11, Vol.132 (47), p.21282-21291

2020

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De Novo Missense Variants in TRAF7 Cause Developmental Delay, Congenital Anomalies, and Dysmorphic Features

Structure- and Property-Based Optimization of Efficient Pan-Bromodomain and Extra Terminal Inhibitors to Identify Oral and Intravenous Candidate I‑BET787

Discovery of GSK251: A Highly Potent, Highly Selective, Orally Bioavailable Inhibitor of PI3Kδ with a Novel Binding Mode

Acetylation of the Catalytic Lysine Inhibits Kinase Activity in PI3Kδ

Durability performance of alkali-activated concrete with pre-treated coarse recycled aggregates for pavements

Diffusion tensor imaging of forearm nerves in humans

Mr-derived cerebral spinal fluid hydrodynamics as a marker and a risk factor for intracranial hypertension in astronauts exposed to microgravity

Water T2 as an early, global and practical biomarker for metabolic syndrome: an observational cross-sectional study

Efficient methods for enol phosphate synthesis using carbon-centred magnesium bases

WHOLE BLOOD T2P LINKS HEMOGLOBIN STATUS TO CARDIOMETABOLIC HEALTH

Simulation of Wood Polymer Composites with Finite Element Analysis

Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2)

Development of Biodegradable Composites Using Polycaprolactone and Bamboo Powder

High strength thin-walled rectangular concrete-filled steel tubular slender beam-columns, Part II: Behavior

Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X‑ray Fragment Screening

Single-Step Microwave-Mediated Synthesis of Oxazoles and Thiazoles from 3-Oxetanone: A Synthetic and Computational Study

Flexural Behavior of Precast Rectangular Reinforced Concrete Beams with Intermediate Connection Filled with High-Performance Concrete

Aptamer-based search for correlates of plasma and serum water T2: implications for early metabolic dysregulation and metabolic syndrome

Artificial neural network model for strength predictions of CFST columns strengthened with CFRP

Discovery of GSK143, a highly potent, selective and orally efficacious spleen tyrosine kinase inhibitor

p38α Mitogen-Activated Protein Kinase Inhibitors: Optimization of a Series of Biphenylamides to Give a Molecule Suitable for Clinical Progression

A practical drug discovery project at the undergraduate level

Investigation of a Bicyclo[1.1.1]pentane as a Phenyl Replacement within an LpPLA 2 Inhibitor

Numerical analysis of axially loaded circular high strength concrete-filled double steel tubular short columns

A Photoaffinity‐Based Fragment‐Screening Platform for Efficient Identification of Protein Ligands

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