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Diethylcarbamoylating/Nitroxylating Agents as Dual Action Inhibitors of Aldehyde Dehydrogenase: A Disulfiram−Cyanamide Merger

Journal of medicinal chemistry, 1999-10, Vol.42 (20), p.4016-4020

1999

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Prodrugs of Nitroxyl and Nitrosobenzene as Cascade Latentiated Inhibitors of Aldehyde Dehydrogenase

Journal of medicinal chemistry, 1998-07, Vol.41 (15), p.2903-2909

1998

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Mechanism for the inhibition of aldehyde dehydrogenase by nitric oxide

Alcohol (Fayetteville, N.Y.), 1997-03, Vol.14 (2), p.181-189

1997

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Inhibition of ALDH3A1-catalyzed oxidation by chlorpropamide analogues

Chemico-biological interactions, 2001-01, Vol.130 (1-3), p.135-149

2001

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Prodrugs of L-cysteine as liver-protective agents. 2(R,S)-methylthiazolidine-4(R)-carboxylic acid (MTCA), a latent cysteine

Journal of medicinal chemistry, 1982-05, Vol.25 (5), p.489-491

1982

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Double-prodrugs of L-cysteine: Differential protection against acetaminophen-induced hepatotoxicity in mice

Journal of biochemical and molecular toxicology, 2002, Vol.16 (5), p.235-244

2002

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Reaction between S-Nitrosothiols and Thiols: Generation of Nitroxyl (HNO) and Subsequent Chemistry

Biochemistry (Easton), 1998-12, Vol.37 (51), p.18129-18129

1998

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Novel Prodrugs of Cyanamide That Inhibit Aldehyde Dehydrogenase in Vivo

Journal of medicinal chemistry, 1997-06, Vol.40 (12), p.1870-1875

1997

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Prodrugs of Nitroxyl as Potential Aldehyde Dehydrogenase Inhibitors vis-a-vis Vascular Smooth Muscle Relaxants

Journal of medicinal chemistry, 1995-05, Vol.38 (11), p.1865-1871

1995

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Augmentation of Human and Rat Lenticular Glutathione in Vitro by Prodrugs of γ-l-Glutamyl-l-cysteine

Journal of medicinal chemistry, 1996-04, Vol.39 (8), p.1676-1681

1996

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Mechanisms of Inhibition of Aldehyde Dehydrogenase by Nitroxyl, the Active Metabolite of the Alcohol Deterrent Agent Cyanamide

Biochemical pharmacology, 1998-06, Vol.55 (12), p.2007-2015

1998

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A Beckmann-type dehydration of n-butyraldoxime catalyzed by cytochrome P-450

Journal of organic chemistry, 1992-09, Vol.57 (19), p.5074-5075

1992

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An HPLC radiotracer method for assessing the ability of L-Cysteine prodrugs to maintain glutathione levels in the cultured rat lens

Current eye research, 1996, Vol.15 (5), p.501-510

1996

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Metabolic depropargylation and its relationship to aldehyde dehydrogenase inhibition in vivo

Journal of medicinal chemistry, 1980-06, Vol.23 (6), p.669-673

1980

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Latent Alkyl Isocyanates as Inhibitors of Aldehyde Dehydrogenase in vivo

Journal of medicinal chemistry, 1994-11, Vol.37 (24), p.4222-4226

1994

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Glutaramyl-.beta.-alanyl Spacer Group for Haptenic Coupling to Proteins. Preparation of Immunogens for Antibody Production against Polychlorinated Biphenyls

Bioconjugate chemistry, 1994-09, Vol.5 (5), p.418-422

1994

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Intermolecular decomposition of N-acylcyanamides

Journal of organic chemistry, 1990-05, Vol.55 (10), p.3403-3406

1990

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beta.-Substituted cysteines as sequestering agents for ethanol-derived acetaldehyde in vivo

Journal of medicinal chemistry, 1987-08, Vol.30 (8), p.1373-1378

1987

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N1-alkyl-substituted derivatives of chlorpropamide as inhibitors of aldehyde dehydrogenase

Journal of medicinal chemistry, 1989-06, Vol.32 (6), p.1335-1340

1989

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N1-Hydroxylated derivatives of chlorpropamide and its analogs as inhibitors of aldehyde dehydrogenase in vivo

Journal of medicinal chemistry, 1992-10, Vol.35 (20), p.3641-3647

1992

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Acyl, N-protected .alpha.-aminoacyl, and peptidyl derivatives as prodrug forms of the alcohol deterrent agent cyanamide

Journal of medicinal chemistry, 1986-10, Vol.29 (10), p.1922-1929

1986

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Relationship of urinary metabolites of theophylline to serum theophylline levels

Clinical pharmacology and therapeutics, 1976-03, Vol.19 (3), p.375-381

1976

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Reaction of Nitroxyl, an Aldehyde Dehydrogenase Inhibitor, with N-Acetyl-L-Cysteine

Alcohol, 2000, Vol.20 (1), p.55-59

2000

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[22] Chemical approaches toward generation of nitroxyl

Methods in Enzymology, 1999, Vol.301, p.211-220

1999

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Propiolaldehyde, a pargyline metabolite that irreversibly inhibits aldehyde dehydrogenase. Isolation from a hepatic microsomal system

Journal of medicinal chemistry, 1979-05, Vol.22 (5), p.463-464

1979

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Rats
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Aldehyde Dehydrogenase - Antagonists & Inhibitors
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Diethylcarbamoylating/Nitroxylating Agents as Dual Action Inhibitors of Aldehyde Dehydrogenase: A Disulfiram−Cyanamide Merger

Prodrugs of Nitroxyl and Nitrosobenzene as Cascade Latentiated Inhibitors of Aldehyde Dehydrogenase

Mechanism for the inhibition of aldehyde dehydrogenase by nitric oxide

Inhibition of ALDH3A1-catalyzed oxidation by chlorpropamide analogues

Prodrugs of L-cysteine as liver-protective agents. 2(R,S)-methylthiazolidine-4(R)-carboxylic acid (MTCA), a latent cysteine

Double-prodrugs of L-cysteine: Differential protection against acetaminophen-induced hepatotoxicity in mice

Reaction between S-Nitrosothiols and Thiols: Generation of Nitroxyl (HNO) and Subsequent Chemistry

Novel Prodrugs of Cyanamide That Inhibit Aldehyde Dehydrogenase in Vivo

Prodrugs of Nitroxyl as Potential Aldehyde Dehydrogenase Inhibitors vis-a-vis Vascular Smooth Muscle Relaxants

Augmentation of Human and Rat Lenticular Glutathione in Vitro by Prodrugs of γ-l-Glutamyl-l-cysteine

Mechanisms of Inhibition of Aldehyde Dehydrogenase by Nitroxyl, the Active Metabolite of the Alcohol Deterrent Agent Cyanamide

A Beckmann-type dehydration of n-butyraldoxime catalyzed by cytochrome P-450

An HPLC radiotracer method for assessing the ability of L-Cysteine prodrugs to maintain glutathione levels in the cultured rat lens

Metabolic depropargylation and its relationship to aldehyde dehydrogenase inhibition in vivo

Latent Alkyl Isocyanates as Inhibitors of Aldehyde Dehydrogenase in vivo

Glutaramyl-.beta.-alanyl Spacer Group for Haptenic Coupling to Proteins. Preparation of Immunogens for Antibody Production against Polychlorinated Biphenyls

Intermolecular decomposition of N-acylcyanamides

beta.-Substituted cysteines as sequestering agents for ethanol-derived acetaldehyde in vivo

N1-alkyl-substituted derivatives of chlorpropamide as inhibitors of aldehyde dehydrogenase

N1-Hydroxylated derivatives of chlorpropamide and its analogs as inhibitors of aldehyde dehydrogenase in vivo

Acyl, N-protected .alpha.-aminoacyl, and peptidyl derivatives as prodrug forms of the alcohol deterrent agent cyanamide

Relationship of urinary metabolites of theophylline to serum theophylline levels

Reaction of Nitroxyl, an Aldehyde Dehydrogenase Inhibitor, with N-Acetyl-L-Cysteine

[22] Chemical approaches toward generation of nitroxyl

Propiolaldehyde, a pargyline metabolite that irreversibly inhibits aldehyde dehydrogenase. Isolation from a hepatic microsomal system

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