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Synthesis and biological activity of 2-anilino-4-(1 H-pyrrol-3-yl) pyrimidine CDK inhibitors

Bioorganic & medicinal chemistry letters, 2004-08, Vol.14 (16), p.4237-4240

2004

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Conformational Changes Associated with Activation of Bee Venom Phospholipase A2

Journal of biochemistry (Tokyo), 1996-12, Vol.120 (6), p.1224-1231

1996

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Differential Binding of Inhibitors to Active and Inactive CDK2 Provides Insights for Drug Design

Chemistry & biology, 2006-02, Vol.13 (2), p.201-211

2006

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The role of inorganic phosphate in regulating the kinetics of inositol 1,4,5-trisphosphate-induced Ca 2+ release: a putative role for endoplasmic reticulum phosphate transporters

Biochimica et biophysica acta. Biomembranes, 1998-08, Vol.1373 (1), p.270-276

1998

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Structural Determinants of CDK4 Inhibition and Design of Selective ATP Competitive Inhibitors

Chemistry & biology, 2004-04, Vol.11 (4), p.525-534

2004

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Effects of thimerosal on the transient kinetics of inositol 1,4,5-trisphosphate-induced Ca2+ release from cerebellar microsomes

Biochemical journal, 1997-07, Vol.325 ( Pt 1) (1), p.177-182

1997

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Opening up Ca2 + stores with lnsP 3

Nature (London), 1995-07, Vol.376 (6538), p.300-301

1995

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Opening up Ca2+ stores with lnsP3

Nature (London), 1995-07, Vol.376 (6538), p.300-301

1995

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The role of inorganic phosphate in regulating the kinetics of inositol 1,4,5-trisphosphate-induced Ca2+ release: a putative role for endoplasmic reticulum phosphate transporters

Biochimica et biophysica acta, 1998-08, Vol.1373 (1), p.270-276

1998

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Inhibition of the cerebellar inositol 1,4,5-trisphosphate-sensitive Ca2+ channel by ethanol and other aliphatic alcohols

Biochemical journal, 1996-02, Vol.314 ( Pt 1) (1), p.175-179

1996

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Discovery and Characterization of 2-Anilino-4- (Thiazol-5-yl)Pyrimidine Transcriptional CDK Inhibitors as Anticancer Agents

Chemistry & biology, 2010-10, Vol.17 (10), p.1111-1121

2010

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The effect of phosphate transporter inhibitors on the InsP3-induced Ca2+ release

Biochemical Society transactions, 1997-08, Vol.25 (3), p.451S-451S

1997

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Biochemical mechanisms of calcium mobilisation induced by mastoparan and chimeric hormone-mastoparan constructs

Cell calcium (Edinburgh), 1998-07, Vol.24 (1), p.27-34

1998

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2-Hydroxycarbazole induces Ca 2+ release from sarcoplasmic reticulum by activating the ryanodine receptor

European journal of pharmacology, 1998, Vol.354 (2), p.245-251

1998

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Subtype identification and functional properties of inositol 1,4,5-trisphosphate receptors in heart and aorta

Pharmacological research, 2000-12, Vol.42 (6), p.581-590

2000

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The effects of thimerosal on the purified InsP3 receptor

Biochemical Society transactions, 1998-08, Vol.26 (3), p.S290-S290

1998

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2-Hydroxycarbazole induces Ca2+ release from sarcoplasmic reticulum by activating the ryanodine receptor

European journal of pharmacology, 1998-08, Vol.354 (2-3), p.245-251

1998

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Modulation of the inositol 1,4,5-trisphosphate-sensitive calcium channel from rat cerebellum by alkali metal ions

Biochemical Society transactions, 1995-08, Vol.23 (3), p.428S-428S

1995

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Effects of aliphatic alcohols on the ER calcium pumps and InsP3 receptors from porcine cerebellum

Biochemical Society transactions, 1996-05, Vol.24 (2), p.292S-292S

1996

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Calcium-mobilizing actions of chimeric hormone-mastoparan peptides

Biochemical Society transactions, 1997-08, Vol.25 (3), p.450S-450S

1997

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Regulation Mechanisms for Phospholipase Enzymes

Mezna, Mokdad

1993

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The effects of cholesterol hemisuccinate and other membrane fluidity perturbing agents on inositol 1,4,5-trisphosphate-induced calcium release from cerebellar microsomes

Biochemical Society transactions, 1995-08, Vol.23 (3), p.429S-429S

1995

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Identification and characterization of inositol 1,4,5-trisphosphate receptors in rat testis

Cell calcium (Edinburgh), 1997-04, Vol.21 (4), p.311-319

1997

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Biochemical mechanisms of calcium mobilisation induced by mastoparan and chimeric hormonewmastoparan constructs

Cell calcium (Edinburgh), 1998-07, Vol.24 (1), p.27-34

1998

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Catch the Kinase Conformer

Chemistry & biology, 2006-07, Vol.13 (7), p.693-694

2006

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Life Sciences & Biomedicine
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Animals
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Biochemistry & Molecular Biology
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Humans
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Calcium - Metabolism
(14)
Cerebellum - Metabolism
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Microsomes - Metabolism
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Microsomes - Drug Effects
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Pharmacology & Pharmacy
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Rats
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Cell Line, Tumor
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Structure-Activity Relationship
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Chemistry, Medicinal
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Kinetics
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Protein Kinase Inhibitors - Pharmacology
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Crystallography, X-Ray
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Inositol 1,4,5-Trisphosphate - Metabolism
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Synthesis and biological activity of 2-anilino-4-(1 H-pyrrol-3-yl) pyrimidine CDK inhibitors

Conformational Changes Associated with Activation of Bee Venom Phospholipase A2

Differential Binding of Inhibitors to Active and Inactive CDK2 Provides Insights for Drug Design

The role of inorganic phosphate in regulating the kinetics of inositol 1,4,5-trisphosphate-induced Ca 2+ release: a putative role for endoplasmic reticulum phosphate transporters

Structural Determinants of CDK4 Inhibition and Design of Selective ATP Competitive Inhibitors

Effects of thimerosal on the transient kinetics of inositol 1,4,5-trisphosphate-induced Ca2+ release from cerebellar microsomes

Opening up Ca2 + stores with lnsP 3

Opening up Ca2+ stores with lnsP3

The role of inorganic phosphate in regulating the kinetics of inositol 1,4,5-trisphosphate-induced Ca2+ release: a putative role for endoplasmic reticulum phosphate transporters

Inhibition of the cerebellar inositol 1,4,5-trisphosphate-sensitive Ca2+ channel by ethanol and other aliphatic alcohols

Discovery and Characterization of 2-Anilino-4- (Thiazol-5-yl)Pyrimidine Transcriptional CDK Inhibitors as Anticancer Agents

The effect of phosphate transporter inhibitors on the InsP3-induced Ca2+ release

Biochemical mechanisms of calcium mobilisation induced by mastoparan and chimeric hormone-mastoparan constructs

2-Hydroxycarbazole induces Ca 2+ release from sarcoplasmic reticulum by activating the ryanodine receptor

Subtype identification and functional properties of inositol 1,4,5-trisphosphate receptors in heart and aorta

The effects of thimerosal on the purified InsP3 receptor

2-Hydroxycarbazole induces Ca2+ release from sarcoplasmic reticulum by activating the ryanodine receptor

Modulation of the inositol 1,4,5-trisphosphate-sensitive calcium channel from rat cerebellum by alkali metal ions

Effects of aliphatic alcohols on the ER calcium pumps and InsP3 receptors from porcine cerebellum

Calcium-mobilizing actions of chimeric hormone-mastoparan peptides

Regulation Mechanisms for Phospholipase Enzymes

The effects of cholesterol hemisuccinate and other membrane fluidity perturbing agents on inositol 1,4,5-trisphosphate-induced calcium release from cerebellar microsomes

Identification and characterization of inositol 1,4,5-trisphosphate receptors in rat testis

Biochemical mechanisms of calcium mobilisation induced by mastoparan and chimeric hormonewmastoparan constructs

Catch the Kinase Conformer

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