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A Computational Modeling and Simulation Approach to Investigate Mechanisms of Subcellular cAMP Compartmentation

PLoS computational biology, 2016-07, Vol.12 (7), p.e1005005-e1005005

2016

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Multi-scale Modeling of the Cardiovascular System: Disease Development, Progression, and Clinical Intervention

Annals of biomedical engineering, 2016-09, Vol.44 (9), p.2642-2660

2016

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Search algorithms as a framework for the optimization of drug combinations

PLoS computational biology, 2008-12, Vol.4 (12), p.e1000249-e1000249

2008

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Effects of Cardiac Troponin I Mutation P83S on Contractile Properties and the Modulation by PKA-Mediated Phosphorylation

The journal of physical chemistry. B, 2016-08, Vol.120 (33), p.8238-8253

2016

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Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin

Journal of the American Heart Association, 2020-02, Vol.9 (3), p.e013518-e013518

2020

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Bitopic Sphingosine 1-Phosphate Receptor 3 (S1P3) Antagonist Rescue from Complete Heart Block: Pharmacological and Genetic Evidence for Direct S1P3 Regulation of Mouse Cardiac Conduction

Molecular pharmacology, 2016-01, Vol.89 (1), p.176-186

2016

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Molecular and Subcellular-Scale Modeling of Nucleotide Diffusion in the Cardiac Myofilament Lattice

Biophysical journal, 2013-11, Vol.105 (9), p.2130-2140

2013

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Patient-specific modeling of dyssynchronous heart failure: A case study

Progress in biophysics and molecular biology, 2011-10, Vol.107 (1), p.147-155

2011

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Regional variations in ex-vivo diffusion tensor anisotropy are associated with cardiomyocyte remodeling in rats after left ventricular pressure overload

Journal of cardiovascular magnetic resonance, 2020-04, Vol.22 (1), p.21-21, Article 21

2020

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Le Cœur en Sabot: shape associations with adverse events in repaired tetralogy of Fallot

Journal of cardiovascular magnetic resonance, 2022-08, Vol.24 (1), p.46-46

2022

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Cardiac-Myocyte-Specific Excision of the Vinculin Gene Disrupts Cellular Junctions, Causing Sudden Death or Dilated Cardiomyopathy

Molecular and Cellular Biology, 2007-11, Vol.27 (21), p.7522-7537

2007

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Direct 3D bioprinting of cardiac micro-tissues mimicking native myocardium

Biomaterials, 2020-10, Vol.256, p.120204-120204, Article 120204

2020

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Cardiac myocyte force development during differentiation and maturation

Annals of the New York Academy of Sciences, 2010-02, Vol.1188 (1), p.121-127

2010

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A demonstration of modularity, reuse, reproducibility, portability and scalability for modeling and simulation of cardiac electrophysiology using Kepler Workflows

PLoS computational biology, 2019-03, Vol.15 (3), p.e1006856-e1006856

2019

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Novel Role for Vinculin in Ventricular Myocyte Mechanics and Dysfunction

Biophysical journal, 2013-04, Vol.104 (7), p.1623-1633

2013

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Calcium and IP3 dynamics in cardiac myocytes: experimental and computational perspectives and approaches

Frontiers in pharmacology, 2014-03, Vol.5, p.35-35

2014

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Charisma and Patronage: Reasoning with Max Weber

McCulloch, Andrew D.

1, 2014

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Nonequilibrium Reactivation of Na+ Current Drives Early Afterdepolarizations in Mouse Ventricle

Circulation. Arrhythmia and electrophysiology, 2014-12, Vol.7 (6), p.1205-1213

2014

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Atlas-Based Computational Analysis of Heart Shape and Function in Congenital Heart Disease

Journal of cardiovascular translational research, 2018-04, Vol.11 (2), p.123-132

2018

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Insights and Challenges of Multi-Scale Modeling of Sarcomere Mechanics in cTn and Tm DCM Mutants-Genotype to Cellular Phenotype

Frontiers in physiology, 2017-03, Vol.8, p.151-151

2017

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Systems Analysis of PKA-Mediated Phosphorylation Gradients in Live Cardiac Myocytes

Proceedings of the National Academy of Sciences - PNAS, 2006-08, Vol.103 (34), p.12923-12928

2006

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Research Priorities for Heart Failure With Preserved Ejection Fraction: National Heart, Lung, and Blood Institute Working Group Summary

Circulation (New York, N.Y.), 2020-03, Vol.141 (12), p.1001-1026

2020

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Right Ventricular Flow Vorticity Relationships With Biventricular Shape in Adult Tetralogy of Fallot

Frontiers in cardiovascular medicine, 2022-01, Vol.8, p.806107-806107

2022

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Modulating the tension-time integral of the cardiac twitch prevents dilated cardiomyopathy in murine hearts

JCI insight, 2020-10, Vol.5 (20)

2020

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High-order finite element methods for cardiac monodomain simulations

Frontiers in physiology, 2015-08, Vol.6, p.217-217

2015

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A Computational Modeling and Simulation Approach to Investigate Mechanisms of Subcellular cAMP Compartmentation

Multi-scale Modeling of the Cardiovascular System: Disease Development, Progression, and Clinical Intervention

Search algorithms as a framework for the optimization of drug combinations

Effects of Cardiac Troponin I Mutation P83S on Contractile Properties and the Modulation by PKA-Mediated Phosphorylation

Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin

Bitopic Sphingosine 1-Phosphate Receptor 3 (S1P3) Antagonist Rescue from Complete Heart Block: Pharmacological and Genetic Evidence for Direct S1P3 Regulation of Mouse Cardiac Conduction

Molecular and Subcellular-Scale Modeling of Nucleotide Diffusion in the Cardiac Myofilament Lattice

Patient-specific modeling of dyssynchronous heart failure: A case study

Regional variations in ex-vivo diffusion tensor anisotropy are associated with cardiomyocyte remodeling in rats after left ventricular pressure overload

Le Cœur en Sabot: shape associations with adverse events in repaired tetralogy of Fallot

Cardiac-Myocyte-Specific Excision of the Vinculin Gene Disrupts Cellular Junctions, Causing Sudden Death or Dilated Cardiomyopathy

Direct 3D bioprinting of cardiac micro-tissues mimicking native myocardium

Cardiac myocyte force development during differentiation and maturation

A demonstration of modularity, reuse, reproducibility, portability and scalability for modeling and simulation of cardiac electrophysiology using Kepler Workflows

Novel Role for Vinculin in Ventricular Myocyte Mechanics and Dysfunction

Calcium and IP3 dynamics in cardiac myocytes: experimental and computational perspectives and approaches

Charisma and Patronage: Reasoning with Max Weber

Nonequilibrium Reactivation of Na+ Current Drives Early Afterdepolarizations in Mouse Ventricle

Atlas-Based Computational Analysis of Heart Shape and Function in Congenital Heart Disease

Insights and Challenges of Multi-Scale Modeling of Sarcomere Mechanics in cTn and Tm DCM Mutants-Genotype to Cellular Phenotype

Systems Analysis of PKA-Mediated Phosphorylation Gradients in Live Cardiac Myocytes

Research Priorities for Heart Failure With Preserved Ejection Fraction: National Heart, Lung, and Blood Institute Working Group Summary

Right Ventricular Flow Vorticity Relationships With Biventricular Shape in Adult Tetralogy of Fallot

Modulating the tension-time integral of the cardiac twitch prevents dilated cardiomyopathy in murine hearts

High-order finite element methods for cardiac monodomain simulations

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