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NY-ESO-1 Protein Formulated in ISCOMATRIX Adjuvant Is a Potent Anticancer Vaccine Inducing Both Humoral and CD8+ T-Cell-Mediated Immunity and Protection against NY-ESO-1+ Tumors

Clinical cancer research, 2004-04, Vol.10 (8), p.2879-2890

2004

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Induction of immunogenic cell death by targeting RIG-I-like helicases in pancreatic cancer

Oncoimmunology, 2014-10, Vol.3 (9), p.e955687-e955687

2014

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Breaking tumor-induced immunosuppression with 5′-triphosphate siRNA silencing TGFβ and activating RIG-I

Oncoimmunology, 2013-05, Vol.2 (5), p.e24170-e24170

2013

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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

Nature (London), 2010-04, Vol.464 (7293), p.1357-1361

2010

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Cancer cells induce interleukin-22 production from memory CD4⁺ T cells via interleukin-1 to promote tumor growth

Proceedings of the National Academy of Sciences - PNAS, 2017-12, Vol.114 (49), p.12994-12999

2017

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Prevailing over T cell exhaustion: New developments in the immunotherapy of pancreatic cancer

Cancer letters, 2016-10, Vol.381 (1), p.259-268

2016

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Impact of a New Fusion Receptor on PD-1-Mediated Immunosuppression in Adoptive T Cell Therapy

JNCI : Journal of the National Cancer Institute, 2015-08, Vol.107 (8), p.1

2015

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Therapeutic Efficacy of Bifunctional siRNA Combining TGF-β1 Silencing with RIG-I Activation in Pancreatic Cancer

Cancer research (Chicago, Ill.), 2013-03, Vol.73 (6), p.1709-1720

2013

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Mitochondrial adaptation in steatotic mice

Mitochondrion, 2018-05, Vol.40, p.1-12

2018

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Immunotherapy in Tumors

Deutsches Ärzteblatt international, 2015-11

2015

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CD103 is a hallmark of tumor‐infiltrating regulatory T cells

International journal of cancer, 2011-11, Vol.129 (10), p.2417-2426

2011

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Isolation of intratumoral leukocytes of TLR-stimulated tumor-bearing mice

Methods in molecular biology (Clifton, N.J.), 2014, Vol.1169, p.175

2014

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To Protect Fatty Livers from Ischemia Reperfusion Injury: Role of Ischemic Postconditioning

Digestive diseases and sciences, 2021-04, Vol.66 (4), p.1349-1359

2021

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Concomitant gemcitabine therapy negatively affects DC vaccine-induced CD8+ T-cell and B-cell responses but improves clinical efficacy in a murine pancreatic carcinoma model

Cancer Immunology, Immunotherapy, 2014-04, Vol.63 (4), p.321-333

2014

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Dying cells expose a nuclear antigen cross-reacting with anti-PD-1 monoclonal antibodies

Scientific reports, 2018-06, Vol.8 (1), p.8810-8, Article 8810

2018

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Systemic but not MDSC-specific IRF4 deficiency promotes an immunosuppressed tumor microenvironment in a murine pancreatic cancer model

Cancer Immunology, Immunotherapy, 2020-10, Vol.69 (10), p.2101-2112

2020

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Multifunctional antitumor molecule 5′‐triphosphate siRNA combining glutaminase silencing and RIG‐I activation

International journal of cancer, 2014-04, Vol.134 (8), p.1958-1971

2014

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ISCOMATRIX adjuvant combines immune activation with antigen delivery to dendritic cells in vivo leading to effective cross-priming of CD8+ T cells

The Journal of immunology (1950), 2011-07, Vol.187 (1), p.55-63

2011

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Su1968 - Balance of NLRP3-Mediated IL-1β and IL-18 Signaling Regulates Colitis Induction in a T Cell Transfer Model of Inflammatory Bowel Disease

Gastroenterology (New York, N.Y. 1943), 2017-04, Vol.152 (5), p.S615-S615

2017

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Tu1763 - NLRP3-Dependent IL-1β Inhibits Cd103+ Dendritic Cell Differentiation in the Gut

Gastroenterology (New York, N.Y. 1943), 2018-05, Vol.154 (6), p.S-1013-S-1013

2018

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Immunotherapy in Tumors: Activated T Cells as a New Treatment Modality

Deutsches Ärzteblatt international, 2015-11, Vol.112 (48), p.809-815

2015

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Abstract 5024: Treatment with synthetic RIG-I agonist triphosphate RNA leads to local and systemic anti-tumor effects in a mouse melanoma tumor model

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.5024-5024

2019

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Presentation of tumour antigens by dendritic cells and challenges faced

Current opinion in immunology, 2010-02, Vol.22 (1), p.137-144

2010

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An ISCOM vaccine combined with a TLR9 agonist breaks immune evasion mediated by regulatory T cells in an orthotopic model of pancreatic carcinoma

International journal of cancer, 2011-02, Vol.128 (4), p.897-907

2011

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Selective bispecific T cell recruiting antibody and antitumor activity of adoptive T cell transfer

JNCI : Journal of the National Cancer Institute, 2015-01, Vol.107 (1), p.364-364

2015

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NY-ESO-1 Protein Formulated in ISCOMATRIX Adjuvant Is a Potent Anticancer Vaccine Inducing Both Humoral and CD8+ T-Cell-Mediated Immunity and Protection against NY-ESO-1+ Tumors

Induction of immunogenic cell death by targeting RIG-I-like helicases in pancreatic cancer

Breaking tumor-induced immunosuppression with 5′-triphosphate siRNA silencing TGFβ and activating RIG-I

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

Cancer cells induce interleukin-22 production from memory CD4⁺ T cells via interleukin-1 to promote tumor growth

Prevailing over T cell exhaustion: New developments in the immunotherapy of pancreatic cancer

Impact of a New Fusion Receptor on PD-1-Mediated Immunosuppression in Adoptive T Cell Therapy

Therapeutic Efficacy of Bifunctional siRNA Combining TGF-β1 Silencing with RIG-I Activation in Pancreatic Cancer

Mitochondrial adaptation in steatotic mice

Immunotherapy in Tumors

CD103 is a hallmark of tumor‐infiltrating regulatory T cells

Isolation of intratumoral leukocytes of TLR-stimulated tumor-bearing mice

To Protect Fatty Livers from Ischemia Reperfusion Injury: Role of Ischemic Postconditioning

Concomitant gemcitabine therapy negatively affects DC vaccine-induced CD8+ T-cell and B-cell responses but improves clinical efficacy in a murine pancreatic carcinoma model

Dying cells expose a nuclear antigen cross-reacting with anti-PD-1 monoclonal antibodies

Systemic but not MDSC-specific IRF4 deficiency promotes an immunosuppressed tumor microenvironment in a murine pancreatic cancer model

Multifunctional antitumor molecule 5′‐triphosphate siRNA combining glutaminase silencing and RIG‐I activation

ISCOMATRIX adjuvant combines immune activation with antigen delivery to dendritic cells in vivo leading to effective cross-priming of CD8+ T cells

Su1968 - Balance of NLRP3-Mediated IL-1β and IL-18 Signaling Regulates Colitis Induction in a T Cell Transfer Model of Inflammatory Bowel Disease

Tu1763 - NLRP3-Dependent IL-1β Inhibits Cd103+ Dendritic Cell Differentiation in the Gut

Immunotherapy in Tumors: Activated T Cells as a New Treatment Modality

Abstract 5024: Treatment with synthetic RIG-I agonist triphosphate RNA leads to local and systemic anti-tumor effects in a mouse melanoma tumor model

Presentation of tumour antigens by dendritic cells and challenges faced

An ISCOM vaccine combined with a TLR9 agonist breaks immune evasion mediated by regulatory T cells in an orthotopic model of pancreatic carcinoma

Selective bispecific T cell recruiting antibody and antitumor activity of adoptive T cell transfer

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