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Targeted Covalent Inhibition of Prolyl Oligopeptidase (POP): Discovery of Sulfonylfluoride Peptidomimetics

Cell chemical biology, 2018-08, Vol.25 (8), p.1031-1037.e4

2018

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CHIPS binds to the phosphorylated N-terminus of the C5a-receptor

Bioorganic & medicinal chemistry letters, 2010-06, Vol.20 (11), p.3338-3340

2010

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Synthesis and Applications of Biomedical and Pharmaceutical Polymers via Click Chemistry Methodologies

Bioconjugate chemistry, 2009-11, Vol.20 (11), p.2001-2016

2009

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Synthesis of a tricyclic hexapeptide –via two consecutive ruthenium-catalyzed macrocyclization steps– with a constrained topology to mimic vancomycin's binding properties toward D-Ala-D-Ala dipeptide

Bioorganic & medicinal chemistry letters, 2022-10, Vol.73, p.128887-128887, Article 128887

2022

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Detection of galectin-3 by novel peptidic photoprobes

Bioorganic & medicinal chemistry letters, 2007-01, Vol.17 (2), p.376-378

2007

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Protein Flexibility and Ligand Rigidity: A Thermodynamic and Kinetic Study of ITAM-Based Ligand Binding to Syk Tandem SH2

Chembiochem : a European journal of chemical biology, 2005-12, Vol.6 (12), p.2261-2270

2005

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Synthesis and Evaluation of TAC-Based Inhibitors of Papain as Mimics of Cystatin B

Chembiochem : a European journal of chemical biology, 2007-11, Vol.8 (16), p.1950-1956

2007

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Specific N-terminal attachment of TMTHSI linkers to native peptides and proteins for strain-promoted azide alkyne cycloaddition

Chemical communications (Cambridge, England), 2023-09, Vol.59 (76), p.11397-114

2023

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TMTHSI, a superior 7-membered ring alkyne containing reagent for strain-promoted azide-alkyne cycloaddition reactions

Chemical science (Cambridge), 2020-08, Vol.11 (33), p.911-916

2020

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Peptides and Proteins as a Continuing Exciting Source of Inspiration for Peptidomimetics

Chembiochem : a European journal of chemical biology, 2011-07, Vol.12 (11), p.1626-1653

2011

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A New Class of Tunable Acid-Sensitive Linkers for Native Drug Release Based on the Trityl Protecting Group

Bioconjugate chemistry, 2022-09, Vol.33 (9), p.1707-1715

2022

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Site-specific N-alkylation of peptides on the solid phase

Tetrahedron letters, 1998-03, Vol.39 (10), p.1243-1246

1998

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Design, development and clinical translation of CriPec®-based core-crosslinked polymeric micelles

Advanced drug delivery reviews, 2022-12, Vol.191, p.114613, Article 114613

2022

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Versatile Click Linker Enabling Native Peptide Release from Nanocarriers upon Redox Trigger

Bioconjugate chemistry, 2023-12, Vol.34 (12), p.2375-2386

2023

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Molecular Construction of Sulfonamide Antisense Oligonucleotides

Journal of organic chemistry, 2019-09, Vol.84 (17), p.10635-10648

2019

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Proteasome inhibition by new dual warhead containing peptido vinyl sulfonyl fluorides

Bioorganic & medicinal chemistry, 2016-08, Vol.24 (16), p.3429-3435

2016

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Tailoring Polyethers for Post-polymerization Functionalization by Cross Metathesis

Organic letters, 2018-04, Vol.20 (8), p.2253-2256

2018

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Characterization and Activity of an Immobilized Antimicrobial Peptide Containing Bactericidal PEG-Hydrogel

Biomacromolecules, 2014-09, Vol.15 (9), p.3390-3395

2014

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Synthesis and Characterization of Enzymatically Biodegradable PEG and Peptide-Based Hydrogels Prepared by Click Chemistry

Biomacromolecules, 2010-06, Vol.11 (6), p.1608-1614

2010

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Glucocorticoid-Loaded Core-Cross-Linked Polymeric Micelles with Tailorable Release Kinetics for Targeted Therapy of Rheumatoid Arthritis

Angewandte Chemie (International ed.), 2012-07, Vol.51 (29), p.7254-7258

International ed. in English, 2012

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Synthesis of tris-tertiary amine CycloTriVeratrilene (TACTV) derivatives as water soluble pre-organized three aromatic ring containing molecular scaffolds for the construction of protein mimics

Tetrahedron letters, 2019-11, Vol.60 (47), p.151245, Article 151245

2019

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An orthogonally protected CycloTriVeratrylene (CTV) as a highly pre-organized molecular scaffold for subsequent ligation of different cyclic peptides towards protein mimics

Bioorganic & medicinal chemistry, 2017-09, Vol.25 (18), p.5008-5015

2017

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A new perspective on fungal metabolites: identification of bioactive compounds from fungi using zebrafish embryogenesis as read-out

Scientific reports, 2019-11, Vol.9 (1), p.17546-16, Article 17546

2019

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Potential peptidic proteasome inhibitors by incorporation of an electrophilic trap based on amino acid derived α-substituted sulfonyl fluorides

Bioorganic & medicinal chemistry, 2017-10, Vol.25 (19), p.5055-5063

2017

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Peptido Sulfonyl Fluorides as New Powerful Proteasome Inhibitors

Journal of medicinal chemistry, 2012-12, Vol.55 (24), p.10995-11003

2012

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Targeted Covalent Inhibition of Prolyl Oligopeptidase (POP): Discovery of Sulfonylfluoride Peptidomimetics

CHIPS binds to the phosphorylated N-terminus of the C5a-receptor

Synthesis and Applications of Biomedical and Pharmaceutical Polymers via Click Chemistry Methodologies

Synthesis of a tricyclic hexapeptide –via two consecutive ruthenium-catalyzed macrocyclization steps– with a constrained topology to mimic vancomycin's binding properties toward D-Ala-D-Ala dipeptide

Detection of galectin-3 by novel peptidic photoprobes

Protein Flexibility and Ligand Rigidity: A Thermodynamic and Kinetic Study of ITAM-Based Ligand Binding to Syk Tandem SH2

Synthesis and Evaluation of TAC-Based Inhibitors of Papain as Mimics of Cystatin B

Specific N-terminal attachment of TMTHSI linkers to native peptides and proteins for strain-promoted azide alkyne cycloaddition

TMTHSI, a superior 7-membered ring alkyne containing reagent for strain-promoted azide-alkyne cycloaddition reactions

Peptides and Proteins as a Continuing Exciting Source of Inspiration for Peptidomimetics

A New Class of Tunable Acid-Sensitive Linkers for Native Drug Release Based on the Trityl Protecting Group

Site-specific N-alkylation of peptides on the solid phase

Design, development and clinical translation of CriPec®-based core-crosslinked polymeric micelles

Versatile Click Linker Enabling Native Peptide Release from Nanocarriers upon Redox Trigger

Molecular Construction of Sulfonamide Antisense Oligonucleotides

Proteasome inhibition by new dual warhead containing peptido vinyl sulfonyl fluorides

Tailoring Polyethers for Post-polymerization Functionalization by Cross Metathesis

Characterization and Activity of an Immobilized Antimicrobial Peptide Containing Bactericidal PEG-Hydrogel

Synthesis and Characterization of Enzymatically Biodegradable PEG and Peptide-Based Hydrogels Prepared by Click Chemistry

Glucocorticoid-Loaded Core-Cross-Linked Polymeric Micelles with Tailorable Release Kinetics for Targeted Therapy of Rheumatoid Arthritis

Synthesis of tris-tertiary amine CycloTriVeratrilene (TACTV) derivatives as water soluble pre-organized three aromatic ring containing molecular scaffolds for the construction of protein mimics

An orthogonally protected CycloTriVeratrylene (CTV) as a highly pre-organized molecular scaffold for subsequent ligation of different cyclic peptides towards protein mimics

A new perspective on fungal metabolites: identification of bioactive compounds from fungi using zebrafish embryogenesis as read-out

Potential peptidic proteasome inhibitors by incorporation of an electrophilic trap based on amino acid derived α-substituted sulfonyl fluorides

Peptido Sulfonyl Fluorides as New Powerful Proteasome Inhibitors

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