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Blockade of Urotensin II Receptor Prevents Vascular Dysfunction

Biomolecules & therapeutics, 2016-09, Vol.24 (5), p.523-528

2016

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Synthesis and SAR investigations of novel 2-arylbenzimidazole derivatives as melanin-concentrating hormone receptor 1 (MCH-R1) antagonists

Bioorganic & medicinal chemistry letters, 2011-04, Vol.21 (8), p.2309-2312

2011

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A novel and orally active poly(ADP-ribose) polymerase inhibitor, KR-33889 [2-[methoxycarbonyl(4-methoxyphenyl) methylsulfanyl]-1H-benzimidazole-4-carboxylic acid amide], attenuates injury in in vitro model of cell death and in vivo model of cardiac ischemia

The Journal of pharmacology and experimental therapeutics, 2009-01, Vol.328 (1), p.10

2009

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Effects of KR-33028, a novel Na+ /H+ exchanger-1 inhibitor, on glutamate-induced neuronal cell death and ischemia-induced cerebral infarct

Brain research, 2009-01, Vol.1248, p.22-30

2009

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(5-Arylfuran-2-ylcarbonyl)guanidines as Cardioprotectives through the Inhibition of Na+/H+ Exchanger Isoform-1

Journal of medicinal chemistry, 2005-04, Vol.48 (8), p.2882-2891

2005

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KR-31466, a Benzopyranylindol Analog, Attenuates Hypoxic Injury Through Mitochondrial KATP Channel and Protein Kinase C Activation in Heart-Derived H9c2 Cells

Journal of Pharmacological Sciences, 2003, Vol.92(1), pp.13-18

2003

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Studies on Benzofuran-7-carboxamides as Poly(ADP-ribose) Polymerase-1 (PARP-1) Inhibitors

Bulletin of the Korean Chemical Society, 2012, 33(4), , pp.1147-1153

2012

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4-Heteroaryl Phthalazin-1(2H)-one Derivatives as Potent Melanin Concentrating Hormone Receptor 1 (MCH-R1) Antagonists

Bulletin of the Korean Chemical Society, 2012, 33(7), , pp.2389-2392

2012

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Pharmacodynamic characteristics and cardioprotective effects of new NHE1 inhibitors

European journal of pharmacology, 2007-07, Vol.567 (1), p.131-138

2007

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Synthesis and Biological Evaluation of 4-Heteroaryl-2-amino-5-methylimidazole Analogs as NHE-1 Inhibitors

Bulletin of the Korean Chemical Society, 2009, 30(11), , pp.2621-2625

2009

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Pharmacological profile of KR-33028, a highly selective inhibitor of Na +/H + exchanger

European journal of pharmacology, 2006-03, Vol.535 (1), p.220-227

2006

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KR-32570, a novel Na+/H+ exchanger-1 inhibitor, attenuates hypoxia-induced cell death through inhibition of intracellular Ca2+ overload and mitochondrial death pathway in H9c2 cells

European journal of pharmacology, 2005-11, Vol.525 (1-3), p.1-7

2005

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KR-33028, a Novel Na + /H + Exchanger-1 Inhibitor, Attenuates Glutamate-Induced Apoptotic Cell Death through Maintaining Mitochondrial Function

Biomolecules & Therapeutics, 2011, 19(4), , pp.445-450

2011

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A novel urotensin II receptor antagonist, KR-36676, prevents ABCA1 repression via ERK/IL-1β pathway

European journal of pharmacology, 2017-05, Vol.803, p.174-178

2017

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Effects of KR-32570, a new Na +/H + exchanger inhibitor, on functional and metabolic impairments produced by global ischemia and reperfusion in the perfused rat heart

European journal of pharmacology, 2005-03, Vol.511 (2), p.175-182

2005

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Computational studies of COX-2 inhibitors: 3D-QSAR and docking

Bioorganic & medicinal chemistry, 2004-04, Vol.12 (7), p.1629-1641

2004

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KR-33028, a Novel Na+/H+ Exchanger-1 Inhibitor, Attenuates Glutamate-Induced Apoptotic Cell Death through Maintaining Mitochondrial Function

Biomolecules & therapeutics, 2011-10, Vol.19 (4), p.445-450

2011

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A urotensin II receptor antagonist, KR36676, decreases vascular remodeling and inflammation in experimental pulmonary hypertension

International immunopharmacology, 2016-11, Vol.40, p.196-202

2016

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Anti-platelet activity of KR-32560, a novel sodium/hydrogen exchanger-1 inhibitor

Pharmacological research, 2006-03, Vol.53 (3), p.265-270

2006

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KR-31831, a new synthetic anti-ischemic agent, inhibits in vivo and in vitro angiogenesis

Experimental & molecular medicine, 2006-10, Vol.38 (5), p.502-508

2006

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Effects of KR-33028, a novel Na+/H+ exchanger-1 inhibitor, on ischemia and reperfusion-induced myocardial infarction in rats and dogs

Fundamental & clinical pharmacology, 2007-06, Vol.21 (3), p.255-263

2007

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A novel urotensin II receptor antagonist, KR-36996, improved cardiac function and attenuated cardiac hypertrophy in experimental heart failure

European journal of pharmacology, 2017-03, Vol.799, p.94-102

2017

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Benzo[b]thiophene-2-carboxamide derivatives as potent urotensin-II receptor antagonists

Bioorganic & medicinal chemistry letters, 2016-10, Vol.26 (19), p.4684-4686

2016

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Solid phase synthesis of biphenyltetrazole derivatives

Tetrahedron letters, 1997-02, Vol.38 (7), p.1203-1206

1997

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Identification of N-(5-(phenoxymethyl)-1,3,4-thiadiazol-2-yl)acetamide derivatives as novel protein tyrosine phosphatase epsilon inhibitors exhibiting anti-osteoclastic activity

Bioorganic & medicinal chemistry, 2018-10, Vol.26 (18), p.5204-5211

2018

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Blockade of Urotensin II Receptor Prevents Vascular Dysfunction

Synthesis and SAR investigations of novel 2-arylbenzimidazole derivatives as melanin-concentrating hormone receptor 1 (MCH-R1) antagonists

A novel and orally active poly(ADP-ribose) polymerase inhibitor, KR-33889 [2-[methoxycarbonyl(4-methoxyphenyl) methylsulfanyl]-1H-benzimidazole-4-carboxylic acid amide], attenuates injury in in vitro model of cell death and in vivo model of cardiac ischemia

Effects of KR-33028, a novel Na+ /H+ exchanger-1 inhibitor, on glutamate-induced neuronal cell death and ischemia-induced cerebral infarct

(5-Arylfuran-2-ylcarbonyl)guanidines as Cardioprotectives through the Inhibition of Na+/H+ Exchanger Isoform-1

KR-31466, a Benzopyranylindol Analog, Attenuates Hypoxic Injury Through Mitochondrial KATP Channel and Protein Kinase C Activation in Heart-Derived H9c2 Cells

Studies on Benzofuran-7-carboxamides as Poly(ADP-ribose) Polymerase-1 (PARP-1) Inhibitors

4-Heteroaryl Phthalazin-1(2H)-one Derivatives as Potent Melanin Concentrating Hormone Receptor 1 (MCH-R1) Antagonists

Pharmacodynamic characteristics and cardioprotective effects of new NHE1 inhibitors

Synthesis and Biological Evaluation of 4-Heteroaryl-2-amino-5-methylimidazole Analogs as NHE-1 Inhibitors

Pharmacological profile of KR-33028, a highly selective inhibitor of Na +/H + exchanger

KR-32570, a novel Na+/H+ exchanger-1 inhibitor, attenuates hypoxia-induced cell death through inhibition of intracellular Ca2+ overload and mitochondrial death pathway in H9c2 cells

KR-33028, a Novel Na + /H + Exchanger-1 Inhibitor, Attenuates Glutamate-Induced Apoptotic Cell Death through Maintaining Mitochondrial Function

A novel urotensin II receptor antagonist, KR-36676, prevents ABCA1 repression via ERK/IL-1β pathway

Effects of KR-32570, a new Na +/H + exchanger inhibitor, on functional and metabolic impairments produced by global ischemia and reperfusion in the perfused rat heart

Computational studies of COX-2 inhibitors: 3D-QSAR and docking

KR-33028, a Novel Na+/H+ Exchanger-1 Inhibitor, Attenuates Glutamate-Induced Apoptotic Cell Death through Maintaining Mitochondrial Function

A urotensin II receptor antagonist, KR36676, decreases vascular remodeling and inflammation in experimental pulmonary hypertension

Anti-platelet activity of KR-32560, a novel sodium/hydrogen exchanger-1 inhibitor

KR-31831, a new synthetic anti-ischemic agent, inhibits in vivo and in vitro angiogenesis

Effects of KR-33028, a novel Na+/H+ exchanger-1 inhibitor, on ischemia and reperfusion-induced myocardial infarction in rats and dogs

A novel urotensin II receptor antagonist, KR-36996, improved cardiac function and attenuated cardiac hypertrophy in experimental heart failure

Benzo[b]thiophene-2-carboxamide derivatives as potent urotensin-II receptor antagonists

Solid phase synthesis of biphenyltetrazole derivatives

Identification of N-(5-(phenoxymethyl)-1,3,4-thiadiazol-2-yl)acetamide derivatives as novel protein tyrosine phosphatase epsilon inhibitors exhibiting anti-osteoclastic activity

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