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Vinylidene chloride: changes in drug-metabolizing enzymes, mutagenicity and relation to its targets for carcinogenesis

Carcinogenesis (New York), 1983-08, Vol.4 (8), p.1031-1038

1983

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A rapid assay for epoxide hydratase activity with benzo(a)pyrene 4,5-(K-region-)oxide as substrate

Analytical biochemistry, 1976-01, Vol.74 (1), p.94-104

1976

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Heterocyclic amines: human carcinogens in cooked food?

Nutrition, metabolism, and cardiovascular diseases, 2001-08, Vol.11 (4 Suppl), p.82

2001

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Characterization of an epithelial, nearly diploid liver cell strain, from Chinese hamster, able to activate promutagens

Mutagenesis, 1987-03, Vol.2 (2), p.127-135

1987

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Microsomal epoxide hydrolase in different rat strains

Biochemical pharmacology, 1983-06, Vol.32 (11), p.1783-1788

1983

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Determination of DNA single strand breaks and selective DNA amplification by N-nitrodimethylamine and analogs, and estimation of the indicator cells' metabolic capacities

Journal of cancer research and clinical oncology, 1986-01, Vol.111 (2), p.123-128

1986

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Hydroquinone Stimulates Granulocyte-Macrophage Progenitor Cells in Vitro and in Vivo

Environmental health perspectives, 1996-12, Vol.104, p.1271

1996

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Prevention of benzo(a)pyrene‐induced mutagenicity by homogeneous epoxide hydratase

International journal of cancer, 1976-10, Vol.18 (4), p.448-452

1976

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Genetically Engineered V79 Chinese Hamster Cells Metabolically Activate the Cytostatic Drugs Cyclophosphamide and Ifosfamide

Environmental health perspectives, 1990-08, Vol.88, p.63-65

1990

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Toxicological Implications of Enzymatic Control of Reactive Metabolites

Human & experimental toxicology, 1990-05, Vol.9 (3), p.171-177

1990

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Inactivation of a Diol Epoxide by Dihydrodiol Dehydrogenase but not by Two Epoxide Hydrolases

Science (American Association for the Advancement of Science), 1982-03, Vol.215 (4539), p.1507-1509

1982

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Tricyclic drugs: potent mutagenicity of traces of a nitroarene formed in the reaction of opipramol with nitrite

Mutation research, 1987, Vol.190 (1), p.7-11

1987

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The formation of 9-hydroxychrysene-1,2-diol as an intermediate in the metabolic activation of chrysene

Carcinogenesis (New York), 1985, Vol.6 (1), p.135-139

1985

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Species differences in activating and inactivating enzymes related to the control of mutagenic metabolites

Archives of toxicology, 1977-01, Vol.39 (1-2), p.97-108

1977

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Determination of epoxide hydrolase activity in whole cells (human lymphocytes) and activation by benzoflavones

Biochemical and biophysical research communications, 1983-01, Vol.110 (2), p.525-529

1983

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Epoxides metabolically produced from some known carcinogens and from some clinically used drugs. I. Differences in mutagenicity

International journal of cancer, 1975-11, Vol.16 (5), p.787-797

1975

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The Epoxide Hydratase Inducer Trans-Stilbene Oxide Shifts the Metabolic Epoxidation of Benzo(a)pyrene from the Bay- to the K-Region and Reduces Its Mutagenicity

Molecular pharmacology, 1979-09, Vol.16 (2), p.656

1979

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Interindividual comparison of epoxide hydratase and glutathione S-transferase activities in cultured human fibroblasts

Carcinogenesis (New York), 1980-04, Vol.1 (4), p.305-309

1980

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A benzo[ a]pyrene metabolite-DNA adduct occurring in the activating cell but not in exogenous DNA

Mutation research, 1987, Vol.190 (1), p.31-34

1987

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Development and validation of alternative metabolic systems for mutagenicity testing in short-term assays

Mutation research, 1996-06, Vol.353 (1), p.151-176

1996

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Benzylic Sulfuric Acid Esters React with Diverse Functional Groups and Often form Secondary Reactive Species

Polycyclic aromatic compounds, 1996-12, Vol.11 (1-4), p.341-348

1996

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Drug metabolism in man and its relationship to that in three rodent species: Monooxygenase, epoxide hydrolase, and glutathione S-transferase activities in subcellular fractions of lung and liver

Biochemical medicine, 1984-08, Vol.32 (1), p.43-56

1984

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Coordinate mutation and transformation of mouse fibroblasts: induction by nitroquinoline oxide and modulation by caffeine

Carcinogenesis (New York), 1981, Vol.2 (12), p.1255-1259

1981

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Metabolic epoxidation of trans-4-acetylaminostilbene: a protective mechanism against its activation to a mutagen

Biochemical and biophysical research communications, 1976-12, Vol.73 (4), p.1025-1029

1976

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Genotoxicity assessment of aromatic amines and amides in genetically engineered V79 cells

Mutation research, 1994-12, Vol.341 (2), p.93

1994

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Vinylidene chloride: changes in drug-metabolizing enzymes, mutagenicity and relation to its targets for carcinogenesis

A rapid assay for epoxide hydratase activity with benzo(a)pyrene 4,5-(K-region-)oxide as substrate

Heterocyclic amines: human carcinogens in cooked food?

Characterization of an epithelial, nearly diploid liver cell strain, from Chinese hamster, able to activate promutagens

Microsomal epoxide hydrolase in different rat strains

Determination of DNA single strand breaks and selective DNA amplification by N-nitrodimethylamine and analogs, and estimation of the indicator cells' metabolic capacities

Hydroquinone Stimulates Granulocyte-Macrophage Progenitor Cells in Vitro and in Vivo

Prevention of benzo(a)pyrene‐induced mutagenicity by homogeneous epoxide hydratase

Genetically Engineered V79 Chinese Hamster Cells Metabolically Activate the Cytostatic Drugs Cyclophosphamide and Ifosfamide

Toxicological Implications of Enzymatic Control of Reactive Metabolites

Inactivation of a Diol Epoxide by Dihydrodiol Dehydrogenase but not by Two Epoxide Hydrolases

Tricyclic drugs: potent mutagenicity of traces of a nitroarene formed in the reaction of opipramol with nitrite

The formation of 9-hydroxychrysene-1,2-diol as an intermediate in the metabolic activation of chrysene

Species differences in activating and inactivating enzymes related to the control of mutagenic metabolites

Determination of epoxide hydrolase activity in whole cells (human lymphocytes) and activation by benzoflavones

Epoxides metabolically produced from some known carcinogens and from some clinically used drugs. I. Differences in mutagenicity

The Epoxide Hydratase Inducer Trans-Stilbene Oxide Shifts the Metabolic Epoxidation of Benzo(a)pyrene from the Bay- to the K-Region and Reduces Its Mutagenicity

Interindividual comparison of epoxide hydratase and glutathione S-transferase activities in cultured human fibroblasts

A benzo[ a]pyrene metabolite-DNA adduct occurring in the activating cell but not in exogenous DNA

Development and validation of alternative metabolic systems for mutagenicity testing in short-term assays

Benzylic Sulfuric Acid Esters React with Diverse Functional Groups and Often form Secondary Reactive Species

Drug metabolism in man and its relationship to that in three rodent species: Monooxygenase, epoxide hydrolase, and glutathione S-transferase activities in subcellular fractions of lung and liver

Coordinate mutation and transformation of mouse fibroblasts: induction by nitroquinoline oxide and modulation by caffeine

Metabolic epoxidation of trans-4-acetylaminostilbene: a protective mechanism against its activation to a mutagen

Genotoxicity assessment of aromatic amines and amides in genetically engineered V79 cells

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