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EEG-β/γ spectral power elevation in rat: a translatable biomarker elicited by GABA(Aα2/3)-positive allosteric modulators at nonsedating anxiolytic doses

Journal of neurophysiology, 2015-01, Vol.113 (1), p.116-131

2015

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Neuroactive Steroids. 1. Positive Allosteric Modulators of the (γ-Aminobutyric Acid)A Receptor: Structure–Activity Relationships of Heterocyclic Substitution at C‑21

Journal of medicinal chemistry, 2015-04, Vol.58 (8), p.3500-3511

2015

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Interaction between positive allosteric modulators and trapping blockers of the NMDA receptor channel

British journal of pharmacology, 2015-03, Vol.172 (5), p.1333-1347

2015

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Altered Histone Acetylation at Glutamate Receptor 2 and Brain-Derived Neurotrophic Factor Genes Is an Early Event Triggered by Status Epilepticus

The Journal of neuroscience, 2002-10, Vol.22 (19), p.8422-8428

2002

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Anticonvulsant profile of the neuroactive steroid, SGE-516, in animal models

Epilepsy research, 2017-08, Vol.134, p.16-25

2017

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The synthetic neuroactive steroid SGE-516 reduces status epilepticus and neuronal cell death in a rat model of soman intoxication

Epilepsy & behavior, 2017-03, Vol.68, p.22-30

2017

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Selective alpha 7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes

Biochemical pharmacology, 2009-10, Vol.78 (7), p.880-888

2009

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Selective α7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes

Biochemical pharmacology, 2009-10, Vol.78 (7), p.880-888

2009

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Trial of SAGE-217 in Patients With Major Depressive Disorder

Obstetrical & gynecological survey, 2019-12, Vol.74 (12), p.723-724

2019

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Metabotropic glutamate receptors modulate feedback inhibition in a developmentally regulated manner in rat dentate gyrus

The Journal of physiology, 2004-12, Vol.561 (2), p.395-401

2004

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Rescue of deficient amygdala tonic γ-aminobutyric acidergic currents in the Fmr-/y mouse model of fragile X syndrome by a novel γ-aminobutyric acid type A receptor-positive allosteric modulator

Journal of neuroscience research, 2016-06, Vol.94 (6), p.568-578

2016

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An ablating 2.6 M⊕ planet in an eccentric binary from the Dispersed Matter Planet Project

Nature astronomy, 2020-04, Vol.4 (4), p.419-426

2020

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Dispersed Matter Planet Project discoveries of ablating planets orbiting nearby bright stars

Nature astronomy, 2020-04, Vol.4 (4), p.408-418

2020

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A Selective Allosteric Potentiator of the M 1 Muscarinic Acetylcholine Receptor Increases Activity of Medial Prefrontal Cortical Neurons and Restores Impairments in Reversal Learning

The Journal of neuroscience, 2009-11, Vol.29 (45), p.14271-14286

2009

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Fimbria-Fornix Lesions Compromise the Induction of Long-Term Potentiation at the Schaffer Collateral-CA1 Synapse in the Rat In Vivo

Journal of neurophysiology, 2005-05, Vol.93 (5), p.3001-3006

2005

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Preventing Phosphorylation of the GABA A R β3 Subunit Compromises the Behavioral Effects of Neuroactive Steroids

Frontiers in molecular neuroscience, 2022, Vol.15, p.817996-817996

2022

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25-Hydroxycholesterol amplifies microglial IL-1[beta] production in an apoE isoform-dependent manner

Journal of neuroinflammation, 2020-06, Vol.17 (1)

2020

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Rescue of deficient amygdala tonic gamma -aminobutyric acidergic currents in the Fmr super(-/y) mouse model of fragile X syndrome by a novel gamma -aminobutyric acid type A receptor-positive allosteric modulator

Journal of neuroscience research, 2016-06, Vol.94 (6), p.568-578

2016

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Rescue of deficient amygdala tonic [gamma]-aminobutyric acidergic currents in the Fmr-/y mouse model of fragile X syndrome by a novel [gamma]-aminobutyric acid type A receptor-positive allosteric modulator

Journal of neuroscience research, 2016-06, Vol.94 (6), p.568

2016

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EEG-β/γ spectral power elevation in rat: a translatable biomarker elicited by GABA Aα2/3 -positive allosteric modulators at nonsedating anxiolytic doses

Journal of neurophysiology, 2015-01, Vol.113 (1), p.116-131

2015

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Natural and Synthetic Neuroactive Steroid Modulators of GABAA and NMDA Receptors

Annual Reports in Medicinal Chemistry, 2014, Vol.49, p.27-42

2014

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SSR alpha and associated calnexin are major calcium binding proteins of the endoplasmic reticulum membrane

The Journal of biological chemistry, 1991-10, Vol.266 (29), p.19599-19610

1991

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Wolf! Wolf!: The Ramifications of Frivolous Appeals

Journal of criminal law, criminology & police science, 1968-03, Vol.59 (1), p.1-3

Doherty, James J.

1968

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Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes

Biochemical pharmacology, 2009-10, Vol.78 (7), p.880-888

2009

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EEG-β/γ spectral power elevation in rat: a translatable biomarker elicited by GABA(Aα2/3)-positive allosteric modulators at nonsedating anxiolytic doses

Neuroactive Steroids. 1. Positive Allosteric Modulators of the (γ-Aminobutyric Acid)A Receptor: Structure–Activity Relationships of Heterocyclic Substitution at C‑21

Interaction between positive allosteric modulators and trapping blockers of the NMDA receptor channel

Altered Histone Acetylation at Glutamate Receptor 2 and Brain-Derived Neurotrophic Factor Genes Is an Early Event Triggered by Status Epilepticus

Anticonvulsant profile of the neuroactive steroid, SGE-516, in animal models

The synthetic neuroactive steroid SGE-516 reduces status epilepticus and neuronal cell death in a rat model of soman intoxication

Selective alpha 7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes

Selective α7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes

Trial of SAGE-217 in Patients With Major Depressive Disorder

Metabotropic glutamate receptors modulate feedback inhibition in a developmentally regulated manner in rat dentate gyrus

Rescue of deficient amygdala tonic γ-aminobutyric acidergic currents in the Fmr-/y mouse model of fragile X syndrome by a novel γ-aminobutyric acid type A receptor-positive allosteric modulator

An ablating 2.6 M⊕ planet in an eccentric binary from the Dispersed Matter Planet Project

Dispersed Matter Planet Project discoveries of ablating planets orbiting nearby bright stars

A Selective Allosteric Potentiator of the M 1 Muscarinic Acetylcholine Receptor Increases Activity of Medial Prefrontal Cortical Neurons and Restores Impairments in Reversal Learning

Fimbria-Fornix Lesions Compromise the Induction of Long-Term Potentiation at the Schaffer Collateral-CA1 Synapse in the Rat In Vivo

Preventing Phosphorylation of the GABA A R β3 Subunit Compromises the Behavioral Effects of Neuroactive Steroids

25-Hydroxycholesterol amplifies microglial IL-1[beta] production in an apoE isoform-dependent manner

Rescue of deficient amygdala tonic gamma -aminobutyric acidergic currents in the Fmr super(-/y) mouse model of fragile X syndrome by a novel gamma -aminobutyric acid type A receptor-positive allosteric modulator

Rescue of deficient amygdala tonic [gamma]-aminobutyric acidergic currents in the Fmr-/y mouse model of fragile X syndrome by a novel [gamma]-aminobutyric acid type A receptor-positive allosteric modulator

EEG-β/γ spectral power elevation in rat: a translatable biomarker elicited by GABA Aα2/3 -positive allosteric modulators at nonsedating anxiolytic doses

Natural and Synthetic Neuroactive Steroid Modulators of GABAA and NMDA Receptors

SSR alpha and associated calnexin are major calcium binding proteins of the endoplasmic reticulum membrane

Wolf! Wolf!: The Ramifications of Frivolous Appeals

Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes

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