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Peptide and protein chemistry approaches to study the tumor suppressor protein p53

Organic & biomolecular chemistry, 2022-07, Vol.2 (28), p.55-559

2022

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Covalent hitchhikers guide proteins to the nucleus

Cell chemical biology, 2024-03, Vol.31 (3), p.383-386

2024

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Disulfide-directed histone ubiquitylation reveals plasticity in hDot1L activation

Nature chemical biology, 2010-04, Vol.6 (4), p.267

2010

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The semisynthesis of site-specifically modified histones and histone-based probes of chromatin-modifying enzymes

Methods (San Diego, Calif.), 2023-07, Vol.215, p.28-37

2023

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Studies of biochemical crosstalk in chromatin with semisynthetic histones

Current opinion in chemical biology, 2018-08, Vol.45, p.27-34

2018

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Chemical Approaches for Studying Histone Modifications

The Journal of biological chemistry, 2010-04, Vol.285 (15), p.11045-11050

2010

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Facile Semisynthesis of Ubiquitylated Peptides with the Ligation Auxiliary 2-Aminooxyethanethiol

Methods in molecular biology (Clifton, N.J.), 2020, Vol.2133, p.293

2020

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All About That Amide Bond: The 6th Chemical Protein Synthesis (CPS) Meeting

Chembiochem : a European journal of chemical biology, 2015-10, Vol.16 (17), p.2531-2536

2015

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The Dehydratase Activity of Lacticin 481 Synthetase is Highly Processive

Journal of the American Chemical Society, 2006-02, Vol.128 (5), p.1420-1421

2006

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Total chemical synthesis of sumoylated histone H4 reveals negative biochemical crosstalk with histone ubiquitylation

Chemical communications (Cambridge, England), 2023-03, Vol.59 (27), p.463-466

2023

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BARD1 is necessary for ubiquitylation of nucleosomal histone H2A and for transcriptional regulation of estrogen metabolism genes

Proceedings of the National Academy of Sciences - PNAS, 2018-02, Vol.115 (6), p.1316-1321

2018

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Semisynthetic, Site-Specific Ubiquitin Modification of α-Synuclein Reveals Differential Effects on Aggregation

Journal of the American Chemical Society, 2012-03, Vol.134 (12), p.5468-5471

2012

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A clickable glutamine (CliQ) derivative for the traceless reversible modification of peptides and proteinsElectronic supplementary information (ESI) available. See DOI: 10.1039/c8cc09404g

2019-02

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Tackling a Curious Case: Generation of Charge-Tagged Guanosine Radicals by Gas-Phase Electron Transfer and Their Characterization by UV–vis Photodissociation Action Spectroscopy and Theory

Journal of the American Society for Mass Spectrometry, 2021-03, Vol.32 (3), p.772-785

2021

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Allosteric Activation of Ubiquitin-Specific Proteases by β-Propeller Proteins UAF1 and WDR20

Molecular cell, 2016-07, Vol.63 (2), p.249-260

2016

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Trimethylation of the R5 Silica‐Precipitating Peptide Increases Silica Particle Size by Redirecting Orthosilicate Binding

Chembiochem : a European journal of chemical biology, 2020-11, Vol.21 (22), p.3208-3211

2020

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All about that Amide Bond: The Sixth Chemical Protein Synthesis (CPS) Meeting

ChemBioChem, 2015-11, Vol.16 (17), p.2531-2536

2015

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Nucleosome Binding by the Lysine Specific Demethylase 1 (LSD1) Enzyme Enables Histone H3 Demethylation

Biochemistry (Easton), 2020-07, Vol.59 (27), p.2479-2483

2020

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Hairpin structure stability plays a role in the activity of two antimicrobial peptides

FEBS letters, 2016-12, Vol.590 (24), p.4480-4488

2016

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Development of Tyrphostin Analogues to Study Inhibition of the Mycobacterium tuberculosis Pup Proteasome System

Chembiochem : a European journal of chemical biology, 2021-11, Vol.22 (21), p.3082-3089

2021

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A clickable glutamine (CliQ) derivative for the traceless reversible modification of peptides and proteins

Chemical communications (Cambridge, England), 2019-02, Vol.55 (14), p.2043-2045

2019

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Fluorescent Probes Reveal a Minimal Ligase Recognition Motif in the Prokaryotic Ubiquitin-like Protein from Mycobacterium tuberculosis

Journal of the American Chemical Society, 2013-02, Vol.135 (8), p.2887-2890

2013

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Rapid Semisynthesis of Acetylated and Sumoylated Histone Analogs

Methods in enzymology, 2016, Vol.574, p.149-165

2016

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A time-resolved FRET assay to measure activity of the deamidase of the prokaryotic ubiquitin-like protein

Analytical biochemistry, 2015-07, Vol.487, p.27-29

2015

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Structure–Activity Analysis of Semisynthetic Nucleosomes: Mechanistic Insights into the Stimulation of Dot1L by Ubiquitylated Histone H2B

ACS chemical biology, 2009-11, Vol.4 (11), p.958-968

2009

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Peptide and protein chemistry approaches to study the tumor suppressor protein p53

Covalent hitchhikers guide proteins to the nucleus

Disulfide-directed histone ubiquitylation reveals plasticity in hDot1L activation

The semisynthesis of site-specifically modified histones and histone-based probes of chromatin-modifying enzymes

Studies of biochemical crosstalk in chromatin with semisynthetic histones

Chemical Approaches for Studying Histone Modifications

Facile Semisynthesis of Ubiquitylated Peptides with the Ligation Auxiliary 2-Aminooxyethanethiol

All About That Amide Bond: The 6th Chemical Protein Synthesis (CPS) Meeting

The Dehydratase Activity of Lacticin 481 Synthetase is Highly Processive

Total chemical synthesis of sumoylated histone H4 reveals negative biochemical crosstalk with histone ubiquitylation

BARD1 is necessary for ubiquitylation of nucleosomal histone H2A and for transcriptional regulation of estrogen metabolism genes

Semisynthetic, Site-Specific Ubiquitin Modification of α-Synuclein Reveals Differential Effects on Aggregation

A clickable glutamine (CliQ) derivative for the traceless reversible modification of peptides and proteinsElectronic supplementary information (ESI) available. See DOI: 10.1039/c8cc09404g

Tackling a Curious Case: Generation of Charge-Tagged Guanosine Radicals by Gas-Phase Electron Transfer and Their Characterization by UV–vis Photodissociation Action Spectroscopy and Theory

Allosteric Activation of Ubiquitin-Specific Proteases by β-Propeller Proteins UAF1 and WDR20

Trimethylation of the R5 Silica‐Precipitating Peptide Increases Silica Particle Size by Redirecting Orthosilicate Binding

All about that Amide Bond: The Sixth Chemical Protein Synthesis (CPS) Meeting

Nucleosome Binding by the Lysine Specific Demethylase 1 (LSD1) Enzyme Enables Histone H3 Demethylation

Hairpin structure stability plays a role in the activity of two antimicrobial peptides

Development of Tyrphostin Analogues to Study Inhibition of the Mycobacterium tuberculosis Pup Proteasome System

A clickable glutamine (CliQ) derivative for the traceless reversible modification of peptides and proteins

Fluorescent Probes Reveal a Minimal Ligase Recognition Motif in the Prokaryotic Ubiquitin-like Protein from Mycobacterium tuberculosis

Rapid Semisynthesis of Acetylated and Sumoylated Histone Analogs

A time-resolved FRET assay to measure activity of the deamidase of the prokaryotic ubiquitin-like protein

Structure–Activity Analysis of Semisynthetic Nucleosomes: Mechanistic Insights into the Stimulation of Dot1L by Ubiquitylated Histone H2B

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