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Mutations in genes encoding the glycine cleavage system predispose to neural tube defects in mice and humans

Human molecular genetics, 2012-04, Vol.21 (7), p.1496-1503

2012

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Fetal spina bifida in a mouse model: loss of neural function in utero

Journal of neurosurgery, 2007-03, Vol.106 (3 Suppl), p.213-221

2007

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Genetic interactions between planar cell polarity genes cause diverse neural tube defects in mice

Disease models & mechanisms, 2014-10, Vol.7 (10), p.1153-1163

2014

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Regulation of cell protrusions by small GTPases during fusion of the neural folds

eLife, 2016-04, Vol.5, p.e13273-e13273

2016

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Mutation of Celsr1 Disrupts Planar Polarity of Inner Ear Hair Cells and Causes Severe Neural Tube Defects in the Mouse

Current biology, 2003-07, Vol.13 (13), p.1129-1133

2003

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Cellular mechanisms underlying Pax3- related neural tube defects and their prevention by folic acid

Disease models & mechanisms, 2019-11, Vol.12 (11)

2019

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Inositol, neural tube closure and the prevention of neural tube defects

Birth defects research, 2017-01, Vol.109 (2), p.68-80

2017

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Glycine Cleavage System H Protein Is Essential for Embryonic Viability, Implying Additional Function Beyond the Glycine Cleavage System

Frontiers in genetics, 2021-01, Vol.12, p.625120-625120

2021

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Dolutegravir in pregnant mice is associated with increased rates of fetal defects at therapeutic but not at supratherapeutic levels

EBioMedicine, 2021-01, Vol.63, p.103167-103167, Article 103167

2021

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Lamin b1 polymorphism influences morphology of the nuclear envelope, cell cycle progression, and risk of neural tube defects in mice

PLoS genetics, 2012-11, Vol.8 (11), p.e1003059-e1003059

2012

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In vivo genetic ablation by Cre-mediated expression of diphtheria toxin fragment A

Genesis (New York, N.Y. : 2000), 2005-11, Vol.43 (3), p.129-135

2005

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Apoptosis is not required for mammalian neural tube closure

Proceedings of the National Academy of Sciences - PNAS, 2009-05, Vol.106 (20), p.8233-8238

2009

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Mouse models of neural tube defects: Investigating preventive mechanisms

American journal of medical genetics. Part C, Seminars in medical genetics, 2005-05, Vol.135C (1), p.31-41

2005

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Regulation of glycine metabolism by the glycine cleavage system and conjugation pathway in mouse models of non‐ketotic hyperglycinemia

Journal of inherited metabolic disease, 2020-11, Vol.43 (6), p.1186-1198

2020

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Deciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal mice

Disease models & mechanisms, 2013-05, Vol.6 (3), p.562-566

2013

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Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening

Disease models & mechanisms, 2013-05, Vol.6 (3), p.571-579

2013

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Disruption of Planar Cell Polarity Signaling Results in Congenital Heart Defects and Cardiomyopathy Attributable to Early Cardiomyocyte Disorganization

Circulation research, 2007-07, Vol.101 (2), p.137-145

2007

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Enabling research with human embryonic and fetal tissue resources

Development (Cambridge), 2015-09, Vol.142 (18), p.3073-3076

2015

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Embryonic Folate Metabolism and Mouse Neural Tube Defects

Science (American Association for the Advancement of Science), 1998-06, Vol.280 (5372), p.2107-2109

1998

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Foregut separation and tracheo-oesophageal malformations: The role of tracheal outgrowth, dorso-ventral patterning and programmed cell death

Developmental biology, 2010-01, Vol.337 (2), p.351-362

2010

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Sonic hedgehog and the molecular regulation of mouse neural tube closure

Development (Cambridge), 2002-05, Vol.129 (10), p.2507-2517

2002

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Genetics of human neural tube defects

Human molecular genetics, 2009-10, Vol.18 (R2), p.R113-R129

2009

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Spina bifida

Nature reviews. Disease primers, 2015-04, Vol.1 (1), p.15007-15007, Article 15007

2015

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Live-Imaging Analysis of Epithelial Zippering During Mouse Neural Tube Closure

Methods in molecular biology (Clifton, N.J.), 2023, Vol.2608, p.147

2023

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Infectious causes of microcephaly: epidemiology, pathogenesis, diagnosis, and management

The Lancet infectious diseases, 2018-01, Vol.18 (1), p.e1-e13

2018

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Mutations in genes encoding the glycine cleavage system predispose to neural tube defects in mice and humans

Fetal spina bifida in a mouse model: loss of neural function in utero

Genetic interactions between planar cell polarity genes cause diverse neural tube defects in mice

Regulation of cell protrusions by small GTPases during fusion of the neural folds

Mutation of Celsr1 Disrupts Planar Polarity of Inner Ear Hair Cells and Causes Severe Neural Tube Defects in the Mouse

Cellular mechanisms underlying Pax3- related neural tube defects and their prevention by folic acid

Inositol, neural tube closure and the prevention of neural tube defects

Glycine Cleavage System H Protein Is Essential for Embryonic Viability, Implying Additional Function Beyond the Glycine Cleavage System

Dolutegravir in pregnant mice is associated with increased rates of fetal defects at therapeutic but not at supratherapeutic levels

Lamin b1 polymorphism influences morphology of the nuclear envelope, cell cycle progression, and risk of neural tube defects in mice

In vivo genetic ablation by Cre-mediated expression of diphtheria toxin fragment A

Apoptosis is not required for mammalian neural tube closure

Mouse models of neural tube defects: Investigating preventive mechanisms

Regulation of glycine metabolism by the glycine cleavage system and conjugation pathway in mouse models of non‐ketotic hyperglycinemia

Deciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal mice

Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening

Disruption of Planar Cell Polarity Signaling Results in Congenital Heart Defects and Cardiomyopathy Attributable to Early Cardiomyocyte Disorganization

Enabling research with human embryonic and fetal tissue resources

Embryonic Folate Metabolism and Mouse Neural Tube Defects

Foregut separation and tracheo-oesophageal malformations: The role of tracheal outgrowth, dorso-ventral patterning and programmed cell death

Sonic hedgehog and the molecular regulation of mouse neural tube closure

Genetics of human neural tube defects

Spina bifida

Live-Imaging Analysis of Epithelial Zippering During Mouse Neural Tube Closure

Infectious causes of microcephaly: epidemiology, pathogenesis, diagnosis, and management

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