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Broadly Neutralizing Antibodies Present New Prospects to Counter Highly Antigenically Diverse Viruses

Science (American Association for the Advancement of Science), 2012-07, Vol.337 (6091), p.183-186

2012

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Broad neutralization coverage of HIV by multiple highly potent antibodies

Nature (London), 2011-09, Vol.477 (7365), p.466-470

2011

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Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target

Science (American Association for the Advancement of Science), 2009-10, Vol.326 (5950), p.285-289

2009

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Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques

Nature medicine, 2009-08, Vol.15 (8), p.951-954

2009

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Rapid and Focused Maturation of a VRC01-Class HIV Broadly Neutralizing Antibody Lineage Involves Both Binding and Accommodation of the N276-Glycan

Immunity (Cambridge, Mass.), 2019-07, Vol.51 (1), p.141-154.e6

2019

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Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (27), p.11181-11186

2011

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A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals

PLoS pathogens, 2010-08, Vol.6 (8), p.e1001028-e1001028

2010

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Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1

Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (25), p.11483-11488

2010

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Toward a more accurate view of human B-cell repertoire by next-generation sequencing, unbiased repertoire capture and single-molecule barcoding

Scientific reports, 2014-10, Vol.4 (1), p.6778, Article 6778

2014

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An MPER antibody neutralizes HIV-1 using germline features shared among donors

Nature communications, 2019-11, Vol.10 (1), p.5389-16, Article 5389

2019

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Human Circulating PD-1+CXCR3−CXCR5+ Memory Tfh Cells Are Highly Functional and Correlate with Broadly Neutralizing HIV Antibody Responses

Immunity (Cambridge, Mass.), 2013-10, Vol.39 (4), p.758-769

2013

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Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies

PLoS pathogens, 2015-08, Vol.11 (8), p.e1005110-e1005110

2015

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Identification of Common Features in Prototype Broadly Neutralizing Antibodies to HIV Envelope V2 Apex to Facilitate Vaccine Design

Immunity (Cambridge, Mass.), 2015-11, Vol.43 (5), p.959-973

2015

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Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

Science (American Association for the Advancement of Science), 2011-09, Vol.333 (6049), p.1633-1637

2011

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CXCL13 is a plasma biomarker of germinal center activity

Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (10), p.2702-2707

2016

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Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort

PLoS pathogens, 2016-01, Vol.12 (1), p.e1005369-e1005369

2016

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Rapid development of glycan-specific, broad, and potent anti–HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque

Proceedings of the National Academy of Sciences - PNAS, 2011-12, Vol.108 (50), p.20125-20129

2011

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A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans

Immunity (Cambridge, Mass.), 2016-07, Vol.45 (1), p.31-45

2016

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HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage

Immunity (Cambridge, Mass.), 2017-11, Vol.47 (5), p.990-1003.e9

2017

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Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers

Immunity (Cambridge, Mass.), 2014-05, Vol.40 (5), p.669-680

2014

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Novel in vitro booster vaccination to rapidly generate antigen-specific human monoclonal antibodies

The Journal of experimental medicine, 2017-08, Vol.214 (8), p.2471-2490

2017

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IDEPI: rapid prediction of HIV-1 antibody epitopes and other phenotypic features from sequence data using a flexible machine learning platform

PLoS computational biology, 2014-09, Vol.10 (9), p.e1003842-e1003842

2014

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Broadly Neutralizing Antibodies Present New Prospects to Counter Highly Antigenically Diverse Viruses

Broad neutralization coverage of HIV by multiple highly potent antibodies

Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target

Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques

Rapid and Focused Maturation of a VRC01-Class HIV Broadly Neutralizing Antibody Lineage Involves Both Binding and Accommodation of the N276-Glycan

Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody

A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals

Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1

Toward a more accurate view of human B-cell repertoire by next-generation sequencing, unbiased repertoire capture and single-molecule barcoding

An MPER antibody neutralizes HIV-1 using germline features shared among donors

Human Circulating PD-1+CXCR3−CXCR5+ Memory Tfh Cells Are Highly Functional and Correlate with Broadly Neutralizing HIV Antibody Responses

Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies

Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies

Identification of Common Features in Prototype Broadly Neutralizing Antibodies to HIV Envelope V2 Apex to Facilitate Vaccine Design

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

CXCL13 is a plasma biomarker of germinal center activity

Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort

Rapid development of glycan-specific, broad, and potent anti–HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque

A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans

Broadly Neutralizing HIV Antibodies Define a Glycan-Dependent Epitope on the Prefusion Conformation of gp41 on Cleaved Envelope Trimers

HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage

Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers

Novel in vitro booster vaccination to rapidly generate antigen-specific human monoclonal antibodies

Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch

IDEPI: rapid prediction of HIV-1 antibody epitopes and other phenotypic features from sequence data using a flexible machine learning platform

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