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USP38 Inhibits Type I Interferon Signaling by Editing TBK1 Ubiquitination through NLRP4 Signalosome

Molecular cell, 2016-10, Vol.64 (2), p.267-281

2016

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The ubiquitin-specific protease USP15 promotes RIG-I-mediated antiviral signaling by deubiquitylating TRIM25

Science signaling, 2014-01, Vol.7 (307), p.ra3

2014

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Induction of OTUD1 by RNA viruses potently inhibits innate immune responses by promoting degradation of the MAVS/TRAF3/TRAF6 signalosome

PLoS pathogens, 2018-05, Vol.14 (5), p.e1007067-e1007067

2018

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Cutting Edge: USP27X Deubiquitinates and Stabilizes the DNA Sensor cGAS to Regulate Cytosolic DNA-Mediated Signaling

The Journal of immunology (1950), 2019-10, Vol.203 (8), p.2049-2054

2019

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Small‐molecule inhibitors of ubiquitin‐specific protease 7 enhance type‐I interferon antiviral efficacy by destabilizing SOCS1

Immunology, 2020-03, Vol.159 (3), p.309-321

2020

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Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells

The Journal of experimental medicine, 2014-08, Vol.211 (9), p.1759-1777

2014

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Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60

PloS one, 2017-12, Vol.12 (12), p.e0189744-e0189744

2017

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OTUD1 Regulates Antifungal Innate Immunity through Deubiquitination of CARD9

The Journal of immunology (1950), 2021-04, Vol.206 (8), p.1832-1843

2021

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Ubiquitin-specific proteases in inflammatory bowel disease-related signalling pathway regulation

Cell death & disease, 2022-02, Vol.13 (2), p.139-139, Article 139

2022

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The emerging role of ubiquitin-specific protease 20 in tumorigenesis and cancer therapeutics

Cell death & disease, 2022-05, Vol.13 (5), p.434-11, Article 434

2022

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Induction of OTUD4 by viral infection promotes antiviral responses through deubiquitinating and stabilizing MAVS

Cell research, 2019-01, Vol.29 (1), p.67-79

2019

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DDIT3 Targets Innate Immunity via the DDIT3-OTUD1-MAVS Pathway To Promote Bovine Viral Diarrhea Virus Replication

Journal of virology, 2021-02, Vol.95 (6)

2021

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Ubiquitin-specific protease 53 promotes osteogenic differentiation of human bone marrow-derived mesenchymal stem cells

Cell death & disease, 2021-03, Vol.12 (3), p.238-15, Article 238

2021

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Inhibition of USP1 enhances anticancer drugs-induced cancer cell death through downregulation of survivin and miR-216a-5p-mediated upregulation of DR5

Cell death & disease, 2022-09, Vol.13 (9), p.821-821, Article 821

2022

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The deubiquitinase OTUD1 inhibits colonic inflammation by suppressing RIPK1-mediated NF-κB signaling

Cellular & molecular immunology, 2022-02, Vol.19 (2), p.276-289

2022

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USP15: a review of its implication in immune and inflammatory processes and tumor progression

Genes and immunity, 2021-05, Vol.22 (1), p.12-23

2021

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CXCR4 up-regulation mediated by USP1 deubiquitination promotes the tumorigenesis and immune escape in esophageal squamous-cell carcinoma

Journal of biochemical and molecular toxicology, 2024-11, Vol.38 (11), p.e70004

2024

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ABRO1 promotes NLRP3 inflammasome activation through regulation of NLRP3 deubiquitination

The EMBO journal, 2019-03, Vol.38 (6), p.n/a

2019

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OTUD4 promotes the progression of glioblastoma by deubiquitinating CDK1 and activating MAPK signaling pathway

Cell death & disease, 2024-03, Vol.15 (3), p.179-179, Article 179

2024

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Mebendazole elicits potent antimyeloma activity by inhibiting the USP5/c-Maf axis

Acta pharmacologica Sinica, 2019-12, Vol.40 (12), p.1568-1577

2019

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OTUD5 promotes innate antiviral and antitumor immunity through deubiquitinating and stabilizing STING

Cellular & molecular immunology, 2021-08, Vol.18 (8), p.1945-1955

2021

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Mixed Lineage Leukemia 5 (MLL5) Protein Stability Is Cooperatively Regulated by O-GlcNac Transferase (OGT) and Ubiquitin Specific Protease 7 (USP7)

PloS one, 2015-12, Vol.10 (12), p.e0145023-e0145023

2015

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Deubiquitinase USP1 enhances CCAAT/enhancer-binding protein beta (C/EBPβ) stability and accelerates adipogenesis and lipid accumulation

Cell death & disease, 2023-11, Vol.14 (11), p.776-776, Article 776

2023

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SRA Suppresses Antiviral Innate Immune Response in Macrophages by Limiting TBK1 K63 Ubiquitination via Deubiquitinase USP15

Microbiology spectrum, 2022-12, Vol.10 (6), p.e0202822-e0202822

2022

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Cutting edge: Ubiquitin-specific protease 4 promotes Th17 cell function under inflammation by deubiquitinating and stabilizing RORγt

The Journal of immunology (1950), 2015-05, Vol.194 (9), p.4094-4097

2015

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USP38 Inhibits Type I Interferon Signaling by Editing TBK1 Ubiquitination through NLRP4 Signalosome

The ubiquitin-specific protease USP15 promotes RIG-I-mediated antiviral signaling by deubiquitylating TRIM25

Induction of OTUD1 by RNA viruses potently inhibits innate immune responses by promoting degradation of the MAVS/TRAF3/TRAF6 signalosome

Cutting Edge: USP27X Deubiquitinates and Stabilizes the DNA Sensor cGAS to Regulate Cytosolic DNA-Mediated Signaling

Small‐molecule inhibitors of ubiquitin‐specific protease 7 enhance type‐I interferon antiviral efficacy by destabilizing SOCS1

Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells

Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60

OTUD1 Regulates Antifungal Innate Immunity through Deubiquitination of CARD9

Ubiquitin-specific proteases in inflammatory bowel disease-related signalling pathway regulation

The emerging role of ubiquitin-specific protease 20 in tumorigenesis and cancer therapeutics

Induction of OTUD4 by viral infection promotes antiviral responses through deubiquitinating and stabilizing MAVS

DDIT3 Targets Innate Immunity via the DDIT3-OTUD1-MAVS Pathway To Promote Bovine Viral Diarrhea Virus Replication

Ubiquitin-specific protease 53 promotes osteogenic differentiation of human bone marrow-derived mesenchymal stem cells

Inhibition of USP1 enhances anticancer drugs-induced cancer cell death through downregulation of survivin and miR-216a-5p-mediated upregulation of DR5

The deubiquitinase OTUD1 inhibits colonic inflammation by suppressing RIPK1-mediated NF-κB signaling

USP15: a review of its implication in immune and inflammatory processes and tumor progression

CXCR4 up-regulation mediated by USP1 deubiquitination promotes the tumorigenesis and immune escape in esophageal squamous-cell carcinoma

ABRO1 promotes NLRP3 inflammasome activation through regulation of NLRP3 deubiquitination

OTUD4 promotes the progression of glioblastoma by deubiquitinating CDK1 and activating MAPK signaling pathway

Mebendazole elicits potent antimyeloma activity by inhibiting the USP5/c-Maf axis

OTUD5 promotes innate antiviral and antitumor immunity through deubiquitinating and stabilizing STING

Mixed Lineage Leukemia 5 (MLL5) Protein Stability Is Cooperatively Regulated by O-GlcNac Transferase (OGT) and Ubiquitin Specific Protease 7 (USP7)

Deubiquitinase USP1 enhances CCAAT/enhancer-binding protein beta (C/EBPβ) stability and accelerates adipogenesis and lipid accumulation

SRA Suppresses Antiviral Innate Immune Response in Macrophages by Limiting TBK1 K63 Ubiquitination via Deubiquitinase USP15

Cutting edge: Ubiquitin-specific protease 4 promotes Th17 cell function under inflammation by deubiquitinating and stabilizing RORγt

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