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Dynamics and ligand-induced conformational changes in human prolyl oligopeptidase analyzed by hydrogen/deuterium exchange mass spectrometry

Scientific reports, 2017-05, Vol.7 (1), p.2456-13, Article 2456

2017

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Substrate Activity Screening (SAS) and Related Approaches in Medicinal Chemistry

ChemMedChem, 2016-03, Vol.11 (5), p.467-476

2016

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Kinetic Investigation of Chemokine Truncation by CD26/Dipeptidyl Peptidase IV Reveals a Striking Selectivity within the Chemokine Family

The Journal of biological chemistry, 2001-08, Vol.276 (32), p.29839-29845

2001

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Structure and function relationship in prolyl oligopeptidase

CNS & neurological disorders drug targets, 2011-05, Vol.10 (3), p.297-305

2011

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Inhibition of dipeptidyl-peptidase IV catalyzed peptide truncation by Vildagliptin ((2S)-{[(3-hydroxyadamantan-1-yl)amino]acetyl}-pyrrolidine-2-carbonitrile)

Biochemical pharmacology, 2005-07, Vol.70 (1), p.134-143

2005

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Prolyl carboxypeptidase purified from human placenta: its characterization and identification as an apelin-cleaving enzyme

Biochimica et biophysica acta, 2016-11, Vol.1864 (11), p.1481-1488

2016

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Kinetic study of the processing by dipeptidyl-peptidase IV/CD26 of neuropeptides involved in pancreatic insulin secretion

FEBS letters, 2001-11, Vol.507 (3), p.327-330

2001

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In vivo profiling of DPP4 inhibitors reveals alterations in collagen metabolism and accumulation of an amyloid peptide in rat plasma

Biochemical pharmacology, 2009-01, Vol.77 (2), p.228-237

2009

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Kinetic investigation of human dipeptidyl peptidase II (DPPII)-mediated hydrolysis of dipeptide derivatives and its identification as quiescent cell proline dipeptidase (QPP)/dipeptidyl peptidase 7 (DPP7)

Biochemical journal, 2005-03, Vol.386 (Pt 2), p.315-324

2005

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The role of the S1 binding site of carboxypeptidase M in substrate specificity and turn-over

Biochimica et biophysica acta, 2007-02, Vol.1774 (2), p.267-277

2007

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P2-Substituted N‑Acylprolylpyrrolidine Inhibitors of Prolyl Oligopeptidase: Biochemical Evaluation, Binding Mode Determination, and Assessment in a Cellular Model of Synucleinopathy

Journal of medicinal chemistry, 2012-11, Vol.55 (22), p.9856-9867

2012

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Validation of a specific prolylcarboxypeptidase activity assay and its suitability for plasma and serum measurements

Analytical biochemistry, 2013-12, Vol.443 (2), p.232-239

2013

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Carboxypeptidase M in apoptosis, adipogenesis and cancer

Clinica chimica acta, 2013-01, Vol.415, p.306-316

2013

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Dipeptidyl peptidase IV substrates. An update on in vitro peptide hydrolysis by human DPPIV

Advances in experimental medicine and biology, 2003, Vol.524, p.3

2003

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Peptide substrates of dipeptidyl peptidases

Advances in experimental medicine and biology, 2006, Vol.575, p.3

2006

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The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes

Proteins, structure, function, and bioinformatics, 1991-01, Vol.10 (1), p.50-69

1991

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Structural determinants for ligand binding and catalysis of  triosephosphate isomerase

European journal of biochemistry, 2001-10, Vol.268 (19), p.5189-5196

2001

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Carboxypeptidase M: Multiple alliances and unknown partners

Clinica chimica acta, 2009, Vol.399 (1), p.24-39

2009

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Glyceraldehyde-phosphate dehydrogenase from Trypanosoma brucei. Comparison of the glycosomal and cytosolic isoenzymes

European journal of biochemistry, 1987-02, Vol.162 (3), p.501-507

1987

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Kinetics of the oxidation of ascorbic acid, ferrocyanide and p‐phenolsulfonic acid by chloroperoxidase compounds I and II

European journal of biochemistry, 1987-02, Vol.163 (1), p.123-127

1987

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Protein engineering of xylose (glucose) isomerase from Actinoplanes missouriensis. 2. Site-directed mutagenesis of the xylose binding site

Biochemistry (Easton), 1992-06, Vol.31 (24), p.5459-5466

1992

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Purification and characterization of dipeptidyl peptidase IV-like enzymes from bovine testes

Frontiers in bioscience, 2008-05, Vol.13 (13), p.3558

2008

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Dynamics and ligand-induced conformational changes in human prolyl oligopeptidase analyzed by hydrogen/deuterium exchange mass spectrometry

Substrate Activity Screening (SAS) and Related Approaches in Medicinal Chemistry

Kinetic Investigation of Chemokine Truncation by CD26/Dipeptidyl Peptidase IV Reveals a Striking Selectivity within the Chemokine Family

Structure and function relationship in prolyl oligopeptidase

Inhibition of dipeptidyl-peptidase IV catalyzed peptide truncation by Vildagliptin ((2S)-{[(3-hydroxyadamantan-1-yl)amino]acetyl}-pyrrolidine-2-carbonitrile)

Prolyl carboxypeptidase purified from human placenta: its characterization and identification as an apelin-cleaving enzyme

Kinetic study of the processing by dipeptidyl-peptidase IV/CD26 of neuropeptides involved in pancreatic insulin secretion

In vivo profiling of DPP4 inhibitors reveals alterations in collagen metabolism and accumulation of an amyloid peptide in rat plasma

Kinetic investigation of human dipeptidyl peptidase II (DPPII)-mediated hydrolysis of dipeptide derivatives and its identification as quiescent cell proline dipeptidase (QPP)/dipeptidyl peptidase 7 (DPP7)

The role of the S1 binding site of carboxypeptidase M in substrate specificity and turn-over

P2-Substituted N‑Acylprolylpyrrolidine Inhibitors of Prolyl Oligopeptidase: Biochemical Evaluation, Binding Mode Determination, and Assessment in a Cellular Model of Synucleinopathy

Validation of a specific prolylcarboxypeptidase activity assay and its suitability for plasma and serum measurements

Carboxypeptidase M in apoptosis, adipogenesis and cancer

Dipeptidyl peptidase IV substrates. An update on in vitro peptide hydrolysis by human DPPIV

Peptide substrates of dipeptidyl peptidases

The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes

Structural determinants for ligand binding and catalysis of  triosephosphate isomerase

Carboxypeptidase M: Multiple alliances and unknown partners

Glyceraldehyde-phosphate dehydrogenase from Trypanosoma brucei. Comparison of the glycosomal and cytosolic isoenzymes

Kinetics of the oxidation of ascorbic acid, ferrocyanide and p‐phenolsulfonic acid by chloroperoxidase compounds I and II

Protein engineering of xylose (glucose) isomerase from Actinoplanes missouriensis. 2. Site-directed mutagenesis of the xylose binding site

Purification and characterization of dipeptidyl peptidase IV-like enzymes from bovine testes

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