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Sphingosine-1-phosphate: From insipid lipid to a key regulator

The Journal of biological chemistry, 2020-03, Vol.295 (10), p.3371-3384

Spiegel, Sarah

2020

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Export of sphingosine-1-phosphate and cancer progression

Journal of lipid research, 2014-09, Vol.55 (9), p.1839-1846

2014

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Revisiting the sphingolipid rheostat: Evolving concepts in cancer therapy

Experimental cell research, 2015-05, Vol.333 (2), p.195-200

2015

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New insights into functions of the sphingosine-1-phosphate transporter SPNS2

Journal of lipid research, 2019-03, Vol.60 (3), p.484-489

2019

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Role of Sphingosine Kinase 1 and Sphingosine-1-Phosphate Axis in Hepatocellular Carcinoma

Lipid Signaling in Human Diseases, 2020-01, p.3-17

2020

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Sphingosine 1-phosphate and ceramide 1-phosphate: expanding roles in cell signaling

Journal of cell science, 2005-10, Vol.118 (20), p.4605-4612

2005

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Targeting SphK1 as a new strategy against cancer

Current drug targets, 2008-08, Vol.9 (8), p.662

2008

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A specific sphingosine kinase 1 inhibitor attenuates airway hyperresponsiveness and inflammation in a mast cell–dependent murine model of allergic asthma

Journal of allergy and clinical immunology, 2013-02, Vol.131 (2), p.501-511.e1

2013

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Sphingosine kinase 1/S1P receptor signaling axis is essential for cellular uptake of Neisseria meningitidis in brain endothelial cells

PLoS pathogens, 2023-11, Vol.19 (11), p.e1011842-e1011842

2023

Volltextzugriff (PDF)

Sphingosine-1-phosphate: the Swiss army knife of sphingolipid signaling

Journal of lipid research, 2009-04, Vol.50 (Suppl), p.S272-S276

2009

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Export and functions of sphingosine-1-phosphate

Biochimica et biophysica acta, 2009-07, Vol.1791 (7), p.692-696

2009

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Role of ABCC1 in export of sphingosine-1-phosphate from mast cells

Proceedings of the National Academy of Sciences - PNAS, 2006-10, Vol.103 (44), p.16394-16399

2006

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Sphingosine-1-phosphate and estrogen signaling in breast cancer

Advances in biological regulation, 2016-01, Vol.60, p.160-165

2016

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Estradiol Induces Export of Sphingosine 1-Phosphate from Breast Cancer Cells via ABCC1 and ABCG2

The Journal of biological chemistry, 2010-04, Vol.285 (14), p.10477-10486

2010

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Regulatory role of SphK1 in TLR7/9‐dependent type I interferon response and autoimmunity

The FASEB journal, 2020-03, Vol.34 (3), p.4329-4347

2020

Volltextzugriff (PDF)

FTY720/fingolimod increases NPC1 and NPC2 expression and reduces cholesterol and sphingolipid accumulation in Niemann‐Pick type C mutant fibroblasts

The FASEB journal, 2017-04, Vol.31 (4), p.1719-1730

2017

Volltextzugriff (PDF)

Sphingosine-1-phosphate: signaling inside and out

FEBS Letters, 2000-06, Vol.476 (1), p.55-57

2000

Volltextzugriff (PDF)

Biological characterization of 3-(2-amino-ethyl)-5-[3-(4-butoxyl-phenyl)-propylidene]-thiazolidine-2,4-dione (K145) as a selective sphingosine kinase-2 inhibitor and anticancer agent

PloS one, 2013-02, Vol.8 (2), p.e56471-e56471

2013

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Generation and metabolism of bioactive sphingosine-1-phosphate

Journal of cellular biochemistry, 2004-08, Vol.92 (5), p.882-899

2004

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Sphingosine-1-phosphate in allergic responses, asthma and anaphylaxis

Pharmacology & therapeutics (Oxford), 2007-09, Vol.115 (3), p.390-399

2007

Volltextzugriff (PDF)

Sphingosine kinase 2 and p62 regulation are determinants of sexual dimorphism in hepatocellular carcinoma

Molecular metabolism (Germany), 2024-08, Vol.86, p.101971, Article 101971

2024

Volltextzugriff (PDF)

The immunosuppressant FTY720 is phosphorylated by sphingosine kinase type 2

FEBS letters, 2003-11, Vol.554 (1-2), p.189-193

2003

Volltextzugriff (PDF)

Sphingosine kinase 1 mediates sexual dimorphism in fibrosis in a mouse model of NASH

Molecular metabolism (Germany), 2022-08, Vol.62, p.101523-101523, Article 101523

2022

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Sphingosine kinase 1 is required for migration, proliferation and survival of MCF-7 human breast cancer cells

FEBS letters, 2005-10, Vol.579 (24), p.5313-5317

2005

Volltextzugriff (PDF)

Sphingosine-1-phosphate: dual messenger functions

FEBS Letters, 2002-10, Vol.531 (1), p.54-57

2002

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Sphingosine-1-phosphate: From insipid lipid to a key regulator

Export of sphingosine-1-phosphate and cancer progression

Revisiting the sphingolipid rheostat: Evolving concepts in cancer therapy

New insights into functions of the sphingosine-1-phosphate transporter SPNS2

Role of Sphingosine Kinase 1 and Sphingosine-1-Phosphate Axis in Hepatocellular Carcinoma

Sphingosine 1-phosphate and ceramide 1-phosphate: expanding roles in cell signaling

Targeting SphK1 as a new strategy against cancer

A specific sphingosine kinase 1 inhibitor attenuates airway hyperresponsiveness and inflammation in a mast cell–dependent murine model of allergic asthma

Sphingosine kinase 1/S1P receptor signaling axis is essential for cellular uptake of Neisseria meningitidis in brain endothelial cells

Sphingosine-1-phosphate: the Swiss army knife of sphingolipid signaling

Export and functions of sphingosine-1-phosphate

Role of ABCC1 in export of sphingosine-1-phosphate from mast cells

Sphingosine-1-phosphate and estrogen signaling in breast cancer

Estradiol Induces Export of Sphingosine 1-Phosphate from Breast Cancer Cells via ABCC1 and ABCG2

Regulatory role of SphK1 in TLR7/9‐dependent type I interferon response and autoimmunity

FTY720/fingolimod increases NPC1 and NPC2 expression and reduces cholesterol and sphingolipid accumulation in Niemann‐Pick type C mutant fibroblasts

Sphingosine-1-phosphate: signaling inside and out

Biological characterization of 3-(2-amino-ethyl)-5-[3-(4-butoxyl-phenyl)-propylidene]-thiazolidine-2,4-dione (K145) as a selective sphingosine kinase-2 inhibitor and anticancer agent

Generation and metabolism of bioactive sphingosine-1-phosphate

Sphingosine-1-phosphate in allergic responses, asthma and anaphylaxis

Sphingosine kinase 2 and p62 regulation are determinants of sexual dimorphism in hepatocellular carcinoma

The immunosuppressant FTY720 is phosphorylated by sphingosine kinase type 2

Sphingosine kinase 1 mediates sexual dimorphism in fibrosis in a mouse model of NASH

Sphingosine kinase 1 is required for migration, proliferation and survival of MCF-7 human breast cancer cells

Sphingosine-1-phosphate: dual messenger functions

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