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Severe Adult Asthmas: Integrating Clinical Features, Biology, and Therapeutics to Improve Outcomes

American journal of respiratory and critical care medicine, 2021-04, Vol.203 (7), p.809-821

Wenzel, Sally E

2021

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Asthma: defining of the persistent adult phenotypes

The Lancet (British edition), 2006-08, Vol.368 (9537), p.804-813

Wenzel, Sally E

2006

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Expression of SARS-CoV-2 receptor ACE2 and coincident host response signature varies by asthma inflammatory phenotype

Journal of allergy and clinical immunology, 2020-08, Vol.146 (2), p.315-324.e7

2020

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Unsupervised phenotyping of Severe Asthma Research Program participants using expanded lung data

Journal of allergy and clinical immunology, 2014-05, Vol.133 (5), p.1280-1288

2014

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Sputum neutrophil counts are associated with more severe asthma phenotypes using cluster analysis

Journal of allergy and clinical immunology, 2014-06, Vol.133 (6), p.1557-1563.e5

2014

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Obesity and asthma: An association modified by age of asthma onset

Journal of allergy and clinical immunology, 2011-06, Vol.127 (6), p.1486-1493.e2

2011

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PEBP1 acts as a rheostat between prosurvival autophagy and ferroptotic death in asthmatic epithelial cells

Proceedings of the National Academy of Sciences - PNAS, 2020-06, Vol.117 (25), p.14376-14385

2020

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Quantitative computed tomographic imaging–based clustering differentiates asthmatic subgroups with distinctive clinical phenotypes

Journal of allergy and clinical immunology, 2017-09, Vol.140 (3), p.690-700.e8

2017

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Mixed Sputum Granulocyte Longitudinal Impact on Lung Function in the Severe Asthma Research Program

American journal of respiratory and critical care medicine, 2021-04, Vol.203 (7), p.882-892

2021

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Key findings and clinical implications from The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study

Journal of allergy and clinical immunology, 2012-08, Vol.130 (2), p.332-342.e10

2012

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Plasma interleukin-6 concentrations, metabolic dysfunction, and asthma severity: a cross-sectional analysis of two cohorts

The lancet respiratory medicine, 2016-07, Vol.4 (7), p.574-584

2016

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Severe asthma: Lessons from the Severe Asthma Research Program

Journal of allergy and clinical immunology, 2007, Vol.119 (1), p.14-21

2007

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Effects of Age and Disease Severity on Systemic Corticosteroid Responses in Asthma

American journal of respiratory and critical care medicine, 2017-06, Vol.195 (11), p.1439-1448

2017

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Distinguishing severe asthma phenotypes: Role of age at onset and eosinophilic inflammation

Journal of allergy and clinical immunology, 2004, Vol.113 (1), p.101-108

2004

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Asthma Is More Severe in Older Adults

PloS one, 2015-07, Vol.10 (7), p.e0133490-e0133490

2015

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Efficacy and safety of an anti–IL-13 mAb in patients with severe asthma: A randomized trial

Journal of allergy and clinical immunology, 2014-04, Vol.133 (4), p.989-996.e4

2014

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High-dimensional profiling clusters asthma severity by lymphoid and non-lymphoid status

Cell reports (Cambridge), 2021-04, Vol.35 (2), p.108974-108974, Article 108974

2021

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IL-4 receptor polymorphisms predict reduction in asthma exacerbations during response to an anti–IL-4 receptor α antagonist

Journal of allergy and clinical immunology, 2012-08, Vol.130 (2), p.516-522.e4

2012

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Pruning of the Pulmonary Vasculature in Asthma. The Severe Asthma Research Program (SARP) Cohort

American journal of respiratory and critical care medicine, 2018-07, Vol.198 (1), p.39-50

2018

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Recent asthma exacerbations: A key predictor of future exacerbations

Respiratory medicine, 2007-03, Vol.101 (3), p.481-489

2007

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Lung function in adults with stable but severe asthma: air trapping and incomplete reversal of obstruction with bronchodilation

Journal of applied physiology (1985), 2008-02, Vol.104 (2), p.394-403

2008

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Complex phenotypes in asthma: Current definitions

Pulmonary pharmacology & therapeutics, 2013-12, Vol.26 (6), p.710-715

Wenzel, Sally E

2013

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Current concepts of severe asthma

The Journal of clinical investigation, 2016-07, Vol.126 (7), p.2394-2403

2016

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IL-27 and type 2 immunity in asthmatic patients: Association with severity, CXCL9, and signal transducer and activator of transcription signaling

Journal of allergy and clinical immunology, 2015-02, Vol.135 (2), p.386-394.e5

2015

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Interleukin-13-induced MUC5AC Is Regulated by 15-Lipoxygenase 1 Pathway in Human Bronchial Epithelial Cells

American journal of respiratory and critical care medicine, 2009-05, Vol.179 (9), p.782-790

2009

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Severe Adult Asthmas: Integrating Clinical Features, Biology, and Therapeutics to Improve Outcomes

Asthma: defining of the persistent adult phenotypes

Expression of SARS-CoV-2 receptor ACE2 and coincident host response signature varies by asthma inflammatory phenotype

Unsupervised phenotyping of Severe Asthma Research Program participants using expanded lung data

Sputum neutrophil counts are associated with more severe asthma phenotypes using cluster analysis

Obesity and asthma: An association modified by age of asthma onset

PEBP1 acts as a rheostat between prosurvival autophagy and ferroptotic death in asthmatic epithelial cells

Quantitative computed tomographic imaging–based clustering differentiates asthmatic subgroups with distinctive clinical phenotypes

Mixed Sputum Granulocyte Longitudinal Impact on Lung Function in the Severe Asthma Research Program

Key findings and clinical implications from The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study

Plasma interleukin-6 concentrations, metabolic dysfunction, and asthma severity: a cross-sectional analysis of two cohorts

Severe asthma: Lessons from the Severe Asthma Research Program

Effects of Age and Disease Severity on Systemic Corticosteroid Responses in Asthma

Distinguishing severe asthma phenotypes: Role of age at onset and eosinophilic inflammation

Asthma Is More Severe in Older Adults

Efficacy and safety of an anti–IL-13 mAb in patients with severe asthma: A randomized trial

High-dimensional profiling clusters asthma severity by lymphoid and non-lymphoid status

IL-4 receptor polymorphisms predict reduction in asthma exacerbations during response to an anti–IL-4 receptor α antagonist

Pruning of the Pulmonary Vasculature in Asthma. The Severe Asthma Research Program (SARP) Cohort

Recent asthma exacerbations: A key predictor of future exacerbations

Lung function in adults with stable but severe asthma: air trapping and incomplete reversal of obstruction with bronchodilation

Complex phenotypes in asthma: Current definitions

Current concepts of severe asthma

IL-27 and type 2 immunity in asthmatic patients: Association with severity, CXCL9, and signal transducer and activator of transcription signaling

Interleukin-13-induced MUC5AC Is Regulated by 15-Lipoxygenase 1 Pathway in Human Bronchial Epithelial Cells

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