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Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase

Nature communications, 2021-02, Vol.12 (1), p.947-947, Article 947

2021

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Identifying potential novel drugs against Helicobacter pylori by targeting the essential response regulator HsrA

Scientific reports, 2019-08, Vol.9 (1), p.11294-13, Article 11294

2019

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Guanine nucleotide binding to the Bateman domain mediates the allosteric inhibition of eukaryotic IMP dehydrogenases

Nature communications, 2015-11, Vol.6 (1), p.8923-8923, Article 8923

2015

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Kinetics and thermodynamics of the protein-ligand interactions in the riboflavin kinase activity of the FAD synthetase from Corynebacterium ammoniagenes

Scientific reports, 2017-08, Vol.7 (1), p.7281-14, Article 7281

2017

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Beyond a platform protein for the degradosome assembly: The Apoptosis-Inducing Factor as an efficient nuclease involved in chromatinolysis

PNAS nexus, 2023-02, Vol.2 (2), p.pgac312-pgac312

2023

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The FAD synthetase from the human pathogen Streptococcus pneumoniae: a bifunctional enzyme exhibiting activity-dependent redox requirements

Scientific reports, 2017-08, Vol.7 (1), p.7609-15, Article 7609

2017

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The trimer interface in the quaternary structure of the bifunctional prokaryotic FAD synthetase from Corynebacterium ammoniagenes

Scientific reports, 2017-03, Vol.7 (1), p.404-404, Article 404

2017

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Streptococcus pneumoniae TIGR4 Flavodoxin: Structural and Biophysical Characterization of a Novel Drug Target

PloS one, 2016-09, Vol.11 (9), p.e0161020-e0161020

2016

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Cytochrome c prompts the recruitment of its nuclear partners SET/TAF-Iβ and NPM1 into biomolecular condensates

iScience, 2024-08, Vol.27 (8), p.110435, Article 110435

2024

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Inhibition of Pig Phosphoenolpyruvate Carboxykinase Isoenzymes by 3-Mercaptopicolinic Acid and Novel Inhibitors

PloS one, 2016-07, Vol.11 (7), p.e0159002-e0159002

2016

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Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity

Nature communications, 2016-02, Vol.7 (1), p.10787-10787, Article 10787

2016

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Structural basis of mitochondrial dysfunction in response to cytochrome c phosphorylation at tyrosine 48

Proceedings of the National Academy of Sciences - PNAS, 2017-04, Vol.114 (15), p.E3041-E3050

2017

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Rational stabilization of complex proteins: a divide and combine approach

Scientific reports, 2015-03, Vol.5 (1), p.9129-9129, Article 9129

2015

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A Quantitative Characterization of Nucleoplasmin/Histone Complexes Reveals Chaperone Versatility

Scientific reports, 2016-08, Vol.6 (1), p.32114-32114, Article 32114

2016

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Allosteric inhibitors of the NS3 protease from the hepatitis C virus

PloS one, 2013-07, Vol.8 (7), p.e69773

2013

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Structural insights into the ability of nucleoplasmin to assemble and chaperone histone octamers for DNA deposition

Scientific reports, 2019-07, Vol.9 (1), p.9487-14, Article 9487

2019

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L-Thyroxine and L-thyroxine-based antimicrobials against Streptococcus pneumoniae and other Gram-positive bacteria

Heliyon, 2024-04, Vol.10 (7), p.e27982-e27982, Article e27982

2024

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Unprecedented pathway of reducing equivalents in a diflavin-linked disulfide oxidoreductase

Proceedings of the National Academy of Sciences - PNAS, 2017-11, Vol.114 (48), p.12725-12730

2017

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Catalytic Efficiency and Vitality of HIV-1 Proteases from African Viral Subtypes

Proceedings of the National Academy of Sciences - PNAS, 2001-05, Vol.98 (11), p.6062-6067

2001

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Structural basis for dual-inhibition mechanism of a non-classical Kazal-type serine protease inhibitor from horseshoe crab in complex with subtilisin

PloS one, 2011-04, Vol.6 (4), p.e18838-e18838

2011

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Identification of a Drug Targeting an Intrinsically Disordered Protein Involved in Pancreatic Adenocarcinoma

Scientific reports, 2017-01, Vol.7 (1), p.39732, Article 39732

2017

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Structural basis for inhibition of the histone chaperone activity of SET/TAF-Iβ by cytochrome c

Proceedings of the National Academy of Sciences - PNAS, 2015-08, Vol.112 (32), p.9908-9913

2015

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Mechanism of the allosteric activation of the ClpP protease machinery by substrates and active-site inhibitors

Science advances, 2019-09, Vol.5 (9), p.eaaw3818-eaaw3818

2019

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Enzyme/Nanocopper Hybrid Nanozymes: Modulating Enzyme-like Activity by the Protein Structure for Biosensing and Tumor Catalytic Therapy

ACS applied materials & interfaces, 2021-02, Vol.13 (4), p.5111-5124

2021

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Deciphering the binding between Nupr1 and MSL1 and their DNA-repairing activity

PloS one, 2013, Vol.8 (10), p.e78101

2013

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Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase

Identifying potential novel drugs against Helicobacter pylori by targeting the essential response regulator HsrA

Guanine nucleotide binding to the Bateman domain mediates the allosteric inhibition of eukaryotic IMP dehydrogenases

Kinetics and thermodynamics of the protein-ligand interactions in the riboflavin kinase activity of the FAD synthetase from Corynebacterium ammoniagenes

Beyond a platform protein for the degradosome assembly: The Apoptosis-Inducing Factor as an efficient nuclease involved in chromatinolysis

The FAD synthetase from the human pathogen Streptococcus pneumoniae: a bifunctional enzyme exhibiting activity-dependent redox requirements

The trimer interface in the quaternary structure of the bifunctional prokaryotic FAD synthetase from Corynebacterium ammoniagenes

Streptococcus pneumoniae TIGR4 Flavodoxin: Structural and Biophysical Characterization of a Novel Drug Target

Cytochrome c prompts the recruitment of its nuclear partners SET/TAF-Iβ and NPM1 into biomolecular condensates

Inhibition of Pig Phosphoenolpyruvate Carboxykinase Isoenzymes by 3-Mercaptopicolinic Acid and Novel Inhibitors

Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity

Structural basis of mitochondrial dysfunction in response to cytochrome c phosphorylation at tyrosine 48

Rational stabilization of complex proteins: a divide and combine approach

A Quantitative Characterization of Nucleoplasmin/Histone Complexes Reveals Chaperone Versatility

Allosteric inhibitors of the NS3 protease from the hepatitis C virus

Structural insights into the ability of nucleoplasmin to assemble and chaperone histone octamers for DNA deposition

L-Thyroxine and L-thyroxine-based antimicrobials against Streptococcus pneumoniae and other Gram-positive bacteria

Unprecedented pathway of reducing equivalents in a diflavin-linked disulfide oxidoreductase

Catalytic Efficiency and Vitality of HIV-1 Proteases from African Viral Subtypes

Structural basis for dual-inhibition mechanism of a non-classical Kazal-type serine protease inhibitor from horseshoe crab in complex with subtilisin

Identification of a Drug Targeting an Intrinsically Disordered Protein Involved in Pancreatic Adenocarcinoma

Structural basis for inhibition of the histone chaperone activity of SET/TAF-Iβ by cytochrome c

Mechanism of the allosteric activation of the ClpP protease machinery by substrates and active-site inhibitors

Enzyme/Nanocopper Hybrid Nanozymes: Modulating Enzyme-like Activity by the Protein Structure for Biosensing and Tumor Catalytic Therapy

Deciphering the binding between Nupr1 and MSL1 and their DNA-repairing activity

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