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Mechanism of mismatch recognition revealed by human MutSβ bound to unpaired DNA loops

Nature structural & molecular biology, 2012-01, Vol.19 (1), p.72-78

2012

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Exploiting the distinctive properties of the bacterial and human MutS homolog sliding clamps on mismatched DNA

The Journal of biological chemistry, 2022-11, Vol.298 (11), p.102505-102505, Article 102505

2022

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Disease-associated repeat instability and mismatch repair

DNA repair, 2016-02, Vol.38, p.117-126

2016

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Elevated MSH2 MSH3 expression interferes with DNA metabolism in vivo

Nucleic acids research, 2023-12, Vol.51 (22), p.12185-12206

2023

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Spontaneous and double-strand break repair-associated quasipalindrome and frameshift mutagenesis in budding yeast: role of mismatch repair

Genetics (Austin), 2024-07, Vol.227 (3)

2024

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Therapeutic validation of MMR-associated genetic modifiers in a human ex vivo model of Huntington disease

American journal of human genetics, 2024-06, Vol.111 (6), p.1165-1183

2024

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Prerecognition Diffusion Mechanism of Human DNA Mismatch Repair Proteins along DNA: Msh2-Msh3 versus Msh2-Msh6

Biochemistry (Easton), 2020-12, Vol.59 (51), p.4822-4832

2020

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Aptamer facilitated purification of functional proteins

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2018-01, Vol.1073, p.201-206

2018

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Complex mutation profiles in mismatch repair and ribonucleotide reductase mutants reveal novel repair substrate specificity of MutS homolog (MSH) complexes

Genetics (Austin), 2022-07, Vol.221 (4)

2022

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Molecular dynamics of mismatch detection—How MutS uses indirect readout to find errors in DNA

Biophysical journal, 2023-08, Vol.122 (15), p.3031-3043

2023

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MutSβ abundance and Msh3 ATP hydrolysis activity are important drivers of CTG•CAG repeat expansions

Nucleic acids research, 2017-09, Vol.45 (17), p.10068-10078

2017

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Genomic Instability Promoted by Overexpression of Mismatch Repair Factors in Yeast: A Model for Understanding Cancer Progression

Genetics (Austin), 2018-06, Vol.209 (2), p.439-456

2018

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MCM9 Is Required for Mammalian DNA Mismatch Repair

Molecular cell, 2015-09, Vol.59 (5), p.831-839

2015

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β Clamp Directs Localization of Mismatch Repair in Bacillus subtilis

Molecular cell, 2008-02, Vol.29 (3), p.291-301

2008

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Coordinated protein and DNA conformational changes govern mismatch repair initiation by MutS

Nucleic acids research, 2018-11, Vol.46 (20), p.10782

2018

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Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer

Journal of clinical oncology, 2017-04, Vol.35 (10), p.1086-1095

2017

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A High Fill-Factor Annular Array of High Frequency Piezoelectric Micromachined Ultrasonic Transducers

Journal of microelectromechanical systems, 2015-08, Vol.24 (4), p.904-913

2015

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Dynamic human MutSα–MutLα complexes compact mismatched DNA

Proceedings of the National Academy of Sciences - PNAS, 2020-07, Vol.117 (28), p.16302-16312

2020

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Recurrent mismatch binding by MutS mobile clamps on DNA localizes repair complexes nearby

Proceedings of the National Academy of Sciences - PNAS, 2020-07, Vol.117 (30), p.17775-17784

2020

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Large conformational changes in MutS during DNA scanning, mismatch recognition and repair signalling

The EMBO journal, 2012-05, Vol.31 (11), p.2528-2540

2012

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Expansion and improvement of ChinaMu by MuT‐seq and chromosome‐level assembly of the Mu‐starter genome

Journal of integrative plant biology, 2024-04, Vol.66 (4), p.645-659

2024

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Suppression of long noncoding RNA NCK1‐AS1 increases chemosensitivity to cisplatin in cervical cancer

Journal of cellular physiology, 2019-04, Vol.234 (4), p.4302-4313

2019

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The Human DNA Mismatch Repair Protein MSH3 Contains Nuclear Localization and Export Signals That Enable Nuclear-Cytosolic Shuttling in Response to Inflammation

Molecular and cellular biology, 2020-06, Vol.40 (13)

2020

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Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells

Cell, 2014-07, Vol.158 (2), p.288-299

2014

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Importance of base-pair opening for mismatch recognition

Nucleic acids research, 2020-11, Vol.48 (20), p.11322-11334

2020

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Mechanism of mismatch recognition revealed by human MutSβ bound to unpaired DNA loops

Exploiting the distinctive properties of the bacterial and human MutS homolog sliding clamps on mismatched DNA

Disease-associated repeat instability and mismatch repair

Elevated MSH2 MSH3 expression interferes with DNA metabolism in vivo

Spontaneous and double-strand break repair-associated quasipalindrome and frameshift mutagenesis in budding yeast: role of mismatch repair

Therapeutic validation of MMR-associated genetic modifiers in a human ex vivo model of Huntington disease

Prerecognition Diffusion Mechanism of Human DNA Mismatch Repair Proteins along DNA: Msh2-Msh3 versus Msh2-Msh6

Aptamer facilitated purification of functional proteins

Complex mutation profiles in mismatch repair and ribonucleotide reductase mutants reveal novel repair substrate specificity of MutS homolog (MSH) complexes

Molecular dynamics of mismatch detection—How MutS uses indirect readout to find errors in DNA

MutSβ abundance and Msh3 ATP hydrolysis activity are important drivers of CTG•CAG repeat expansions

Genomic Instability Promoted by Overexpression of Mismatch Repair Factors in Yeast: A Model for Understanding Cancer Progression

MCM9 Is Required for Mammalian DNA Mismatch Repair

β Clamp Directs Localization of Mismatch Repair in Bacillus subtilis

Coordinated protein and DNA conformational changes govern mismatch repair initiation by MutS

Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer

A High Fill-Factor Annular Array of High Frequency Piezoelectric Micromachined Ultrasonic Transducers

Dynamic human MutSα–MutLα complexes compact mismatched DNA

Recurrent mismatch binding by MutS mobile clamps on DNA localizes repair complexes nearby

Large conformational changes in MutS during DNA scanning, mismatch recognition and repair signalling

Expansion and improvement of ChinaMu by MuT‐seq and chromosome‐level assembly of the Mu‐starter genome

Suppression of long noncoding RNA NCK1‐AS1 increases chemosensitivity to cisplatin in cervical cancer

The Human DNA Mismatch Repair Protein MSH3 Contains Nuclear Localization and Export Signals That Enable Nuclear-Cytosolic Shuttling in Response to Inflammation

Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells

Importance of base-pair opening for mismatch recognition

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