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Synthesis and Characterization of Thiophosphoramidate Morpholino Oligonucleotides and Chimeras

Journal of the American Chemical Society, 2020-09, Vol.142 (38), p.16240-16253

2020

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Anti-Inflammatory Effect of Anti-TNF‑α SiRNA Cationic Phosphorus Dendrimer Nanocomplexes Administered Intranasally in a Murine Acute Lung Injury Model

Biomacromolecules, 2017-08, Vol.18 (8), p.2379-2388

2017

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Synthesis and Biophysical Studies of High-Affinity Morpholino Oligomers Containing G‑Clamp Analogs

Journal of organic chemistry, 2023-11, Vol.88 (21), p.15168-15175

2023

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Targeted Delivery of Antisense Oligonucleotides Using Neurotensin Peptides

Journal of medicinal chemistry, 2020-08, Vol.63 (15), p.8471-8484

2020

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Polyethylene-Glycol-Modified Single-Walled Carbon Nanotubes for Intra-Articular Delivery to Chondrocytes

ACS nano, 2014-12, Vol.8 (12), p.12280-12291

2014

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Conditional gene knockdowns in sea urchins using caged morpholinos

Developmental biology, 2021-07, Vol.475, p.21-29

2021

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A comparative analysis of peptide-delivered antisense antibiotics using diverse nucleotide mimics

RNA (Cambridge), 2024-05, Vol.30 (6), p.624

2024

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5′-Morpholino modification of the sense strand of an siRNA makes it a more effective passenger

Chemical communications (Cambridge, England), 2019-04, Vol.55 (35), p.5139-5142

2019

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Inhibition of Pseudomonas aeruginosa by Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers

Antimicrobial agents and chemotherapy, 2017-04, Vol.61 (4)

2017

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Combinatorial control of gene function with wavelength-selective caged morpholinos

Methods in enzymology, 2019, Vol.624, p.69-88

2019

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Sequential Gene Silencing Using Wavelength-Selective Caged Morpholino Oligonucleotides

Angewandte Chemie (International ed.), 2014-09, Vol.53 (38), p.10114-10118

International ed. in English, 2014

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Structural insights into the morpholino nucleic acid/RNA duplex using the new XNA builder Ducque in a molecular modeling pipeline

Nucleic acids research, 2024-04, Vol.52 (6), p.2836

2024

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Practical Synthesis of Quinoline-Protected Morpholino Oligomers for Light-Triggered Regulation of Gene Function

Molecules (Basel, Switzerland), 2020-04, Vol.25 (9), p.2078

2020

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Synthesis of Phosphorodiamidate Morpholino Oligonucleotides and Their Chimeras Using Phosphoramidite Chemistry

Journal of the American Chemical Society, 2016-12, Vol.138 (48), p.15663-15672

2016

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Inhibition of SARS-CoV-2 in Vero cell cultures by peptide-conjugated morpholino oligomers

Journal of antimicrobial chemotherapy, 2021-01, Vol.76 (2), p.413-417

2021

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Rational optimization of siRNA to ensure strand bias in the interaction with the RNA-induced silencing complex

Chemical communications (Cambridge, England), 2023-05, Vol.59 (42), p.6347-635

2023

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A targeted antisense therapeutic approach for Hutchinson-Gilford progeria syndrome

Nature medicine, 2021-03, Vol.27 (3), p.536-545

2021

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C5-pyrimidine-functionalized morpholino oligonucleotides exhibit differential binding affinity, target specificity and lipophilicity

Organic & biomolecular chemistry, 2023-02, Vol.21 (6), p.1242-1253

2023

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A novel morpholino oligomer targeting ISS-N1 improves rescue of severe spinal muscular atrophy transgenic mice

Human gene therapy, 2013-03, Vol.24 (3), p.331

2013

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Organocatalytic Ring-Opening Polymerization of Morpholinones: New Strategies to Functionalized Polyesters

Journal of the American Chemical Society, 2014-07, Vol.136 (26), p.9252-9255

2014

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Invention and Early History of Morpholinos: From Pipe Dream to Practical Products

Methods in molecular biology (Clifton, N.J.), 2017-01, Vol.1565, p.1

Summerton, James E

2017

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Identification of a Peptide for Systemic Brain Delivery of a Morpholino Oligonucleotide in Mouse Models of Spinal Muscular Atrophy

Nucleic acid therapeutics, 2017-06, Vol.27 (3), p.130

2017

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Exploring site‐specific activation of bis‐N,N’‐dialkylaminophosphordiamidites and the synthesis of morpholinophosphoramidate oligonucleotides

FEBS letters, 2019-07, Vol.593 (13), p.1459-1467

2019

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Gene-Silencing Antisense Oligomers Inhibit Acinetobacter Growth In Vitro and In Vivo

The Journal of infectious diseases, 2013-11, Vol.208 (10), p.1553-1560

2013

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Drug-free macromolecular therapeutics: Impact of structure on induction of apoptosis in Raji B cells

Journal of controlled release, 2017-10, Vol.263, p.139-150

2017

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Synthesis and Characterization of Thiophosphoramidate Morpholino Oligonucleotides and Chimeras

Anti-Inflammatory Effect of Anti-TNF‑α SiRNA Cationic Phosphorus Dendrimer Nanocomplexes Administered Intranasally in a Murine Acute Lung Injury Model

Synthesis and Biophysical Studies of High-Affinity Morpholino Oligomers Containing G‑Clamp Analogs

Targeted Delivery of Antisense Oligonucleotides Using Neurotensin Peptides

Polyethylene-Glycol-Modified Single-Walled Carbon Nanotubes for Intra-Articular Delivery to Chondrocytes

Conditional gene knockdowns in sea urchins using caged morpholinos

A comparative analysis of peptide-delivered antisense antibiotics using diverse nucleotide mimics

5′-Morpholino modification of the sense strand of an siRNA makes it a more effective passenger

Inhibition of Pseudomonas aeruginosa by Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers

Combinatorial control of gene function with wavelength-selective caged morpholinos

Sequential Gene Silencing Using Wavelength-Selective Caged Morpholino Oligonucleotides

Structural insights into the morpholino nucleic acid/RNA duplex using the new XNA builder Ducque in a molecular modeling pipeline

Practical Synthesis of Quinoline-Protected Morpholino Oligomers for Light-Triggered Regulation of Gene Function

Synthesis of Phosphorodiamidate Morpholino Oligonucleotides and Their Chimeras Using Phosphoramidite Chemistry

Inhibition of SARS-CoV-2 in Vero cell cultures by peptide-conjugated morpholino oligomers

Rational optimization of siRNA to ensure strand bias in the interaction with the RNA-induced silencing complex

A targeted antisense therapeutic approach for Hutchinson-Gilford progeria syndrome

C5-pyrimidine-functionalized morpholino oligonucleotides exhibit differential binding affinity, target specificity and lipophilicity

A novel morpholino oligomer targeting ISS-N1 improves rescue of severe spinal muscular atrophy transgenic mice

Organocatalytic Ring-Opening Polymerization of Morpholinones: New Strategies to Functionalized Polyesters

Invention and Early History of Morpholinos: From Pipe Dream to Practical Products

Identification of a Peptide for Systemic Brain Delivery of a Morpholino Oligonucleotide in Mouse Models of Spinal Muscular Atrophy

Exploring site‐specific activation of bis‐N,N’‐dialkylaminophosphordiamidites and the synthesis of morpholinophosphoramidate oligonucleotides

Gene-Silencing Antisense Oligomers Inhibit Acinetobacter Growth In Vitro and In Vivo

Drug-free macromolecular therapeutics: Impact of structure on induction of apoptosis in Raji B cells

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