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Concise Review: Induced Pluripotent Stem Cell‐Based Drug Discovery for Mitochondrial Disease

Stem cells (Dayton, Ohio), 2017-07, Vol.35 (7), p.1655-1662

2017

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Generation of two mother–child pairs of iPSCs from maternally inherited Leigh syndrome patients with m.8993 T > G and m.9176 T > G MT-ATP6 mutations

Stem cell research, 2023-03, Vol.67, p.103030-103030, Article 103030

2023

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Teriflunomide as a therapeutic means for myelin repair

Journal of neuroinflammation, 2023-01, Vol.20 (1), p.7-7, Article 7

2023

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RNA-based generation of iPSCs from a boy carrying the mutation m.9185 T>C in the mitochondrial gene MT-ATP6 and from his healthy mother

Stem cell research, 2022-10, Vol.64, p.102920-102920, Article 102920

2022

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TLR4 Associated Signaling Disrupters as a New Means to Overcome HERV-W Envelope-Mediated Myelination Deficits

Frontiers in cellular neuroscience, 2021-11, Vol.15, p.777542-777542

2021

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High-content screening of mitochondrial polarization in neural cells derived from human pluripotent stem cells

STAR protocols, 2022-09, Vol.3 (3), p.101602, Article 101602

2022

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Generation of Human iPSC-derived Neural Progenitor Cells (NPCs) as Drug Discovery Model for Neurological and Mitochondrial Disorders

Bio-protocol, 2021-03, Vol.11 (5), p.e3939-e3939

2021

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Generation of four iPSC lines from four patients with Leigh syndrome carrying homoplasmic mutations m.8993T > G or m.8993T > C in the mitochondrial gene MT-ATP6

Stem cell research, 2022-05, Vol.61, p.102742-102742, Article 102742

2022

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High-content analysis of neuronal morphology in human iPSC-derived neurons

STAR protocols, 2022-09, Vol.3 (3), p.101567-101567, Article 101567

2022

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Nuclear inclusions of pathogenic ataxin-1 induce oxidative stress and perturb the protein synthesis machinery

Redox biology, 2020-05, Vol.32, p.101458-101458, Article 101458

2020

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Assessment of Ethanol-Induced Toxicity on iPSC-Derived Human Neurons Using a Novel High-Throughput Mitochondrial Neuronal Health (MNH) Assay

Frontiers in cell and developmental biology, 2020-11, Vol.8, p.590540

2020

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Mitochondria in neurogenesis: Implications for mitochondrial diseases

Stem cells (Dayton, Ohio), 2021-10, Vol.39 (10), p.1289-1297

2021

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Pluripotent Stem Cells for Uncovering the Role of Mitochondria in Human Brain Function and Dysfunction

Journal of molecular biology, 2018-03, Vol.430 (7), p.891-903

2018

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A Novel Gene Controls a New Structure: PiggyBac Transposable Element-Derived 1, Unique to Mammals, Controls Mammal-Specific Neuronal Paraspeckles

Molecular biology and evolution, 2022-10, Vol.39 (10)

2022

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Signals of Pig Ancestry in Wild Boar, Sus scrofa, from Eastern Austria: Current Hybridisation or Incomplete Gene Pool Differentiation and Historical Introgressions?

Diversity (Basel), 2023-06, Vol.15 (6), p.790

2023

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CRISPR/Cas9-edited PKP2 knock-out (JMUi001-A-2) and DSG2 knock-out (JMUi001-A-3) iPSC lines as an isogenic human model system for arrhythmogenic cardiomyopathy (ACM)

Stem cell research, 2021-05, Vol.53, p.102256, Article 102256

2021

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Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome

Human iPSC-Derived Neural Progenitors Are an Effective Drug Discovery Model for Neurological mtDNA Disorders

Concise Review: Induced Pluripotent Stem Cell‐Based Drug Discovery for Mitochondrial Disease

Generation of two mother–child pairs of iPSCs from maternally inherited Leigh syndrome patients with m.8993 T > G and m.9176 T > G MT-ATP6 mutations

Teriflunomide as a therapeutic means for myelin repair

RNA-based generation of iPSCs from a boy carrying the mutation m.9185 T>C in the mitochondrial gene MT-ATP6 and from his healthy mother

TLR4 Associated Signaling Disrupters as a New Means to Overcome HERV-W Envelope-Mediated Myelination Deficits

High-content screening of mitochondrial polarization in neural cells derived from human pluripotent stem cells

Generation of Human iPSC-derived Neural Progenitor Cells (NPCs) as Drug Discovery Model for Neurological and Mitochondrial Disorders

Generation of four iPSC lines from four patients with Leigh syndrome carrying homoplasmic mutations m.8993T > G or m.8993T > C in the mitochondrial gene MT-ATP6

High-content analysis of neuronal morphology in human iPSC-derived neurons

Nuclear inclusions of pathogenic ataxin-1 induce oxidative stress and perturb the protein synthesis machinery

Assessment of Ethanol-Induced Toxicity on iPSC-Derived Human Neurons Using a Novel High-Throughput Mitochondrial Neuronal Health (MNH) Assay

Mitochondria in neurogenesis: Implications for mitochondrial diseases

Pluripotent Stem Cells for Uncovering the Role of Mitochondria in Human Brain Function and Dysfunction

A Novel Gene Controls a New Structure: PiggyBac Transposable Element-Derived 1, Unique to Mammals, Controls Mammal-Specific Neuronal Paraspeckles

Signals of Pig Ancestry in Wild Boar, Sus scrofa, from Eastern Austria: Current Hybridisation or Incomplete Gene Pool Differentiation and Historical Introgressions?

CRISPR/Cas9-edited PKP2 knock-out (JMUi001-A-2) and DSG2 knock-out (JMUi001-A-3) iPSC lines as an isogenic human model system for arrhythmogenic cardiomyopathy (ACM)

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