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Interrupting the Nazarov reaction: domino and cascade processes utilizing cyclopentenyl cations

Chemical communications (Cambridge, England), 2009-01 (38), p.5676-5688

2009

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Comprehensive in vitro characterization of PD-L1 small molecule inhibitors

Scientific reports, 2019-08, Vol.9 (1), p.12392-19, Article 12392

2019

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Dual Probes for Positron Emission Tomography (PET) and Fluorescence Imaging (FI) of Cancer

Pharmaceutics, 2022-03, Vol.14 (3), p.645

2022

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Inhibition of triple negative breast cancer metastasis and invasiveness by novel drugs that target epithelial to mesenchymal transition

Scientific reports, 2021-06, Vol.11 (1), p.11757-15, Article 11757

2021

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Repurposing Antimalarial Pyronaridine as a DNA Repair Inhibitor to Exploit the Full Potential of Gold-Nanoparticle-Mediated Radiation Response

Pharmaceutics, 2022-12, Vol.14 (12), p.2795

2022

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The Pan-Canadian Chemical Library: A Mechanism to Open Academic Chemistry to High-Throughput Virtual Screening

Scientific data, 2024-06, Vol.11 (1), p.597-13

2024

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Structure-Based Discovery of Allosteric Inhibitors Targeting a New Druggable Site in the Respiratory Syncytial Virus Polymerase

ACS omega, 2024-05, Vol.9 (20), p.22213-22229

2024

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Modulation of ERCC1-XPF Heterodimerization Inhibition via Structural Modification of Small Molecule Inhibitor Side-Chains

Frontiers in oncology, 2022-03, Vol.12, p.819172-819172

2022

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Proof of concept: Pull down assay using bovine serum albumin and an immunomodulator small molecule

Heliyon, 2023-11, Vol.9 (11), p.e21408-e21408, Article e21408

2023

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Organoaluminum-Mediated Interrupted Nazarov Reaction

Angewandte Chemie (International ed.), 2013-08, Vol.52 (33), p.8616-8619

International ed. in English, 2013

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New Efficient Iterative Approaches to Polycyclic Ethers

Chemistry : a European journal, 2002-10, Vol.8 (19), p.4346-4353

2002

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Efficient Trapping of 1,2-Cyclohexadienes with 1,3-Dipoles

Chemistry : a European journal, 2016-07, Vol.22 (31), p.10763-10767

2016

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Radiopharmacological evaluation of 6-deoxy-6-[18 F]fluoro- d -fructose as a radiotracer for PET imaging of GLUT5 in breast cancer

Nuclear medicine and biology, 2011-05, Vol.38 (4), p.461-475

2011

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Design, synthesis, and evaluation of positron emission tomography/fluorescence dual imaging probes for targeting facilitated glucose transporter 1 (GLUT1)

Organic & biomolecular chemistry, 2021-04, Vol.19 (14), p.3241-3254

2021

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Probing amino acid side chains of the integral membrane protein PagP by solution NMR: Side chain immobilization facilitates association of secondary structures

Biochimica et biophysica acta. Biomembranes, 2024-03, Vol.1866 (3), p.184281-184281, Article 184281

2024

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The calcium sensitizer drug MCI-154 binds the structural C-terminal domain of cardiac troponin C

Biochemistry and biophysics reports, 2018-12, Vol.16, p.145-151

2018

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1,4-Diketones from Cross-Conjugated Dienones: Potassium Permanganate-Interrupted Nazarov Reaction

Angewandte Chemie (International ed.), 2015-08, Vol.54 (34), p.9940-9943

International ed. in English, 2015

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Heteroaromatic Trapping of Tricyclic 2-Oxidocyclopentenyl Cations: A Surprisingly Efficient Example of Intermolecular Interrupted Nazarov Reaction

Heterocycles, 2010-03, Vol.80 (2), p.1413

2010

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Pharmacological targets and emerging treatments for respiratory syncytial virus bronchiolitis

Pharmacology & therapeutics (Oxford), 2021-04, Vol.220, p.107712-107712, Article 107712

2021

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Targeting DNA Repair in Tumor Cells via Inhibition of ERCC1–XPF

Journal of medicinal chemistry, 2019-09, Vol.62 (17), p.7684-7696

2019

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Enhancing the activity of platinum-based drugs by improved inhibitors of ERCC1–XPF-mediated DNA repair

Cancer chemotherapy and pharmacology, 2021-02, Vol.87 (2), p.259-267

2021

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Computer‐aided drug design of small molecule inhibitors of the ERCC1‐XPF protein–protein interaction

Chemical biology & drug design, 2020-04, Vol.95 (4), p.460-471

2020

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Recent advances in the Stevens rearrangement of ammonium ylides. Application to the synthesis of alkaloid natural products

Tetrahedron, 2006-02, Vol.62 (6), p.1043-1062

2006

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Design, synthesis and in vitro cell-free/cell-based biological evaluations of novel ERCC1-XPF inhibitors targeting DNA repair pathway

European journal of medicinal chemistry, 2020-10, Vol.204, p.112658-112658, Article 112658

2020

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Tunable GLUT–Hexose Binding and Transport via Modulation of Hexose C‐3 Hydrogen‐Bonding Capabilities

Chemistry : a European journal, 2017-06, Vol.23 (33), p.8073-8081

2017

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Interrupting the Nazarov reaction: domino and cascade processes utilizing cyclopentenyl cations

Comprehensive in vitro characterization of PD-L1 small molecule inhibitors

Dual Probes for Positron Emission Tomography (PET) and Fluorescence Imaging (FI) of Cancer

Inhibition of triple negative breast cancer metastasis and invasiveness by novel drugs that target epithelial to mesenchymal transition

Repurposing Antimalarial Pyronaridine as a DNA Repair Inhibitor to Exploit the Full Potential of Gold-Nanoparticle-Mediated Radiation Response

The Pan-Canadian Chemical Library: A Mechanism to Open Academic Chemistry to High-Throughput Virtual Screening

Structure-Based Discovery of Allosteric Inhibitors Targeting a New Druggable Site in the Respiratory Syncytial Virus Polymerase

Modulation of ERCC1-XPF Heterodimerization Inhibition via Structural Modification of Small Molecule Inhibitor Side-Chains

Proof of concept: Pull down assay using bovine serum albumin and an immunomodulator small molecule

Organoaluminum-Mediated Interrupted Nazarov Reaction

New Efficient Iterative Approaches to Polycyclic Ethers

Efficient Trapping of 1,2-Cyclohexadienes with 1,3-Dipoles

Radiopharmacological evaluation of 6-deoxy-6-[18 F]fluoro- d -fructose as a radiotracer for PET imaging of GLUT5 in breast cancer

Design, synthesis, and evaluation of positron emission tomography/fluorescence dual imaging probes for targeting facilitated glucose transporter 1 (GLUT1)

Probing amino acid side chains of the integral membrane protein PagP by solution NMR: Side chain immobilization facilitates association of secondary structures

The calcium sensitizer drug MCI-154 binds the structural C-terminal domain of cardiac troponin C

1,4-Diketones from Cross-Conjugated Dienones: Potassium Permanganate-Interrupted Nazarov Reaction

Heteroaromatic Trapping of Tricyclic 2-Oxidocyclopentenyl Cations: A Surprisingly Efficient Example of Intermolecular Interrupted Nazarov Reaction

Pharmacological targets and emerging treatments for respiratory syncytial virus bronchiolitis

Targeting DNA Repair in Tumor Cells via Inhibition of ERCC1–XPF

Enhancing the activity of platinum-based drugs by improved inhibitors of ERCC1–XPF-mediated DNA repair

Computer‐aided drug design of small molecule inhibitors of the ERCC1‐XPF protein–protein interaction

Recent advances in the Stevens rearrangement of ammonium ylides. Application to the synthesis of alkaloid natural products

Design, synthesis and in vitro cell-free/cell-based biological evaluations of novel ERCC1-XPF inhibitors targeting DNA repair pathway

Tunable GLUT–Hexose Binding and Transport via Modulation of Hexose C‐3 Hydrogen‐Bonding Capabilities

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