UB Paderborn / Katalog / Suche / in CDI

Small-Molecule Inhibitors of the Hedgehog Signaling Pathway as Cancer Therapeutics

ChemMedChem, 2010-04, Vol.5 (4), p.500-512

2010

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Nivolumab Plus Ipilimumab Versus EXTREME Regimen as First-Line Treatment for Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck: The Final Results of CheckMate 651

Journal of clinical oncology, 2023-04, Vol.41 (12), p.2166-2180

2023

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Discovery of NVP-LEQ506, a Second-Generation Inhibitor of Smoothened

ChemMedChem, 2013-08, Vol.8 (8), p.1261-1265

2013

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Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist

ACS medicinal chemistry letters, 2010-06, Vol.1 (3), p.130-134

2010

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The Role of the Acidity of N‑Heteroaryl Sulfonamides as Inhibitors of Bcl‑2 Family Protein–Protein Interactions

ACS medicinal chemistry letters, 2013-02, Vol.4 (2), p.186-190

2013

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A method for estimating the risk of drug-induced phototoxicity and its application to smoothened inhibitors

MedChemComm, 2011-10, Vol.2 (10), p.973

2011

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Crosstalk between hedgehog and other signaling pathways as a basis for combination therapies in cancer

Cancer treatment reviews, 2014-07, Vol.40 (6), p.750-759

2014

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Regioselectivity and enantioselectivity in nickel-catalysed reductive coupling reactions of alkynes

Chemical communications (Cambridge, England), 2007-01 (43), p.4441-4449

2007

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1-Amino-4-benzylphthalazines as Orally Bioavailable Smoothened Antagonists with Antitumor Activity

Journal of medicinal chemistry, 2009-07, Vol.52 (13), p.3954-3968

2009

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Small-Molecule Inhibitors of the Hedgehog Signaling Pathway as Cancer Therapeutics

Nivolumab Plus Ipilimumab Versus EXTREME Regimen as First-Line Treatment for Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck: The Final Results of CheckMate 651

Discovery of NVP-LEQ506, a Second-Generation Inhibitor of Smoothened

Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist

The Role of the Acidity of N‑Heteroaryl Sulfonamides as Inhibitors of Bcl‑2 Family Protein–Protein Interactions

A method for estimating the risk of drug-induced phototoxicity and its application to smoothened inhibitors

Crosstalk between hedgehog and other signaling pathways as a basis for combination therapies in cancer

Regioselectivity and enantioselectivity in nickel-catalysed reductive coupling reactions of alkynes

Efficacy and Safety of Nivolumab Plus Ipilimumab vs Nivolumab Alone for Treatment of Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck: The Phase 2 CheckMate 714 Randomized Clinical Trial

1-Amino-4-benzylphthalazines as Orally Bioavailable Smoothened Antagonists with Antitumor Activity

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