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Contemporary Diversity of β-Lactamases among Enterobacteriaceae in the Nine U.S. Census Regions and Ceftazidime-Avibactam Activity Tested against Isolates Producing the Most Prevalent β-Lactamase Groups

Antimicrobial Agents and Chemotherapy, 2014-02, Vol.58 (2), p.833-838

2014

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Distinctive Binding of Avibactam to Penicillin-Binding Proteins of Gram-Negative and Gram-Positive Bacteria

Antimicrobial agents and chemotherapy, 2016-02, Vol.60 (2), p.752-756

2016

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Plazomicin Retains Antibiotic Activity against Most Aminoglycoside Modifying Enzymes

ACS infectious diseases, 2018-06, Vol.4 (6), p.980-987

2018

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Telavancin, a Multifunctional Lipoglycopeptide, Disrupts both Cell Wall Synthesis and Cell Membrane Integrity in Methicillin-Resistant Staphylococcus aureus

Antimicrobial Agents and Chemotherapy, 2005-03, Vol.49 (3), p.1127-1134

2005

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Aminoglycosides: An Overview

Cold Spring Harbor perspectives in medicine, 2016-06, Vol.6 (6), p.a027029

2016

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Antistaphylococcal Activity of TD-1792, a Multivalent Glycopeptide-Cephalosporin Antibiotic

Antimicrobial Agents and Chemotherapy, 2012-03, Vol.56 (3), p.1584-1587

2012

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Comparative Surveillance Study of Telavancin Activity against Recently Collected Gram-Positive Clinical Isolates from across the United States

Antimicrobial Agents and Chemotherapy, 2008-07, Vol.52 (7), p.2383-2388

2008

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In Vitro Activity of Telavancin against Resistant Gram-Positive Bacteria

Antimicrobial Agents and Chemotherapy, 2008-07, Vol.52 (7), p.2647-2652

2008

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Plazomicin for Infections Caused by Carbapenem-Resistant Enterobacteriaceae

The New England journal of medicine, 2019-02, Vol.380 (8), p.791-793

2019

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Intrapulmonary Distribution of Intravenous Telavancin in Healthy Subjects and Effect of Pulmonary Surfactant on In Vitro Activities of Telavancin and Other Antibiotics

Antimicrobial Agents and Chemotherapy, 2008-01, Vol.52 (1), p.92-97

2008

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Once-Daily Plazomicin for Complicated Urinary Tract Infections

The New England journal of medicine, 2019-02, Vol.380 (8), p.729-740

2019

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Activity of plazomicin compared with other aminoglycosides against isolates from European and adjacent countries, including Enterobacteriaceae molecularly characterized for aminoglycoside-modifying enzymes and other resistance mechanisms

Journal of antimicrobial chemotherapy, 2018-12, Vol.73 (12), p.3346-3354

2018

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The Continued Value of Disk Diffusion for Assessing Antimicrobial Susceptibility in Clinical Laboratories: Report from the Clinical and Laboratory Standards Institute Methods Development and Standardization Working Group

Journal of clinical microbiology, 2018-08, Vol.56 (8)

2018

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Bactericidal activity, absence of serum effect, and time-kill kinetics of ceftazidime-avibactam against β-lactamase-producing Enterobacteriaceae and Pseudomonas aeruginosa

Antimicrobial agents and chemotherapy, 2014-09, Vol.58 (9), p.5297-5305

2014

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Specificity of Induction of the vanA and vanB Operons in Vancomycin-Resistant Enterococci by Telavancin

Antimicrobial Agents and Chemotherapy, 2010-07, Vol.54 (7), p.2814-2818

2010

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Plazomicin activity against polymyxin-resistant Enterobacteriaceae, including MCR-1-producing isolates

Journal of antimicrobial chemotherapy, 2017-10, Vol.72 (10), p.2787-2791

2017

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Efficacy of Telavancin (TD-6424), a Rapidly Bactericidal Lipoglycopeptide with Multiple Mechanisms of Action, in a Murine Model of Pneumonia Induced by Methicillin-Resistant Staphylococcus aureus

Antimicrobial Agents and Chemotherapy, 2005-10, Vol.49 (10), p.4344-4346

2005

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Hydrophobic Vancomycin Derivatives with Improved ADME Properties: Discovery of Telavancin (TD-6424)

The Journal of Antibiotics, 2004/05/25, Vol.57(5), pp.326-336

2004

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Plazomicin Is Active Against Metallo-β-Lactamase-Producing Enterobacteriaceae

Open forum infectious diseases, 2019-04, Vol.6 (4), p.ofz123-ofz123

2019

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Potent LpxC Inhibitors with In Vitro Activity against Multidrug-Resistant Pseudomonas aeruginosa

Antimicrobial agents and chemotherapy, 2019-11, Vol.63 (11)

2019

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In Vitro Activities of Ceftazidime-Avibactam, Aztreonam-Avibactam, and a Panel of Older and Contemporary Antimicrobial Agents against Carbapenemase-Producing Gram-Negative Bacilli

Antimicrobial agents and chemotherapy, 2015-12, Vol.59 (12), p.7842-7846

2015

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In vitro activity of Plazomicin against Enterobacteriaceae isolates carrying genes encoding aminoglycoside-modifying enzymes most common in US Census divisions

Diagnostic microbiology and infectious disease, 2019-05, Vol.94 (1), p.73-77

2019

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Pharmacodynamics of plazomicin and a comparator aminoglycoside, amikacin, studied in an in vitro pharmacokinetic model of infection

International journal of antimicrobial agents, 2019-11, Vol.54 (5), p.626-632

2019

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ARGONAUT II Study of the In Vitro Activity of Plazomicin against Carbapenemase-Producing Klebsiella pneumoniae

Antimicrobial agents and chemotherapy, 2020-04, Vol.64 (5)

2020

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Contemporary Diversity of β-Lactamases among Enterobacteriaceae in the Nine U.S. Census Regions and Ceftazidime-Avibactam Activity Tested against Isolates Producing the Most Prevalent β-Lactamase Groups

Distinctive Binding of Avibactam to Penicillin-Binding Proteins of Gram-Negative and Gram-Positive Bacteria

Plazomicin Retains Antibiotic Activity against Most Aminoglycoside Modifying Enzymes

Telavancin, a Multifunctional Lipoglycopeptide, Disrupts both Cell Wall Synthesis and Cell Membrane Integrity in Methicillin-Resistant Staphylococcus aureus

Aminoglycosides: An Overview

Antistaphylococcal Activity of TD-1792, a Multivalent Glycopeptide-Cephalosporin Antibiotic

Comparative Surveillance Study of Telavancin Activity against Recently Collected Gram-Positive Clinical Isolates from across the United States

In Vitro Activity of Telavancin against Resistant Gram-Positive Bacteria

Plazomicin for Infections Caused by Carbapenem-Resistant Enterobacteriaceae

Intrapulmonary Distribution of Intravenous Telavancin in Healthy Subjects and Effect of Pulmonary Surfactant on In Vitro Activities of Telavancin and Other Antibiotics

Once-Daily Plazomicin for Complicated Urinary Tract Infections

Activity of plazomicin compared with other aminoglycosides against isolates from European and adjacent countries, including Enterobacteriaceae molecularly characterized for aminoglycoside-modifying enzymes and other resistance mechanisms

The Continued Value of Disk Diffusion for Assessing Antimicrobial Susceptibility in Clinical Laboratories: Report from the Clinical and Laboratory Standards Institute Methods Development and Standardization Working Group

Bactericidal activity, absence of serum effect, and time-kill kinetics of ceftazidime-avibactam against β-lactamase-producing Enterobacteriaceae and Pseudomonas aeruginosa

Specificity of Induction of the vanA and vanB Operons in Vancomycin-Resistant Enterococci by Telavancin

Plazomicin activity against polymyxin-resistant Enterobacteriaceae, including MCR-1-producing isolates

Efficacy of Telavancin (TD-6424), a Rapidly Bactericidal Lipoglycopeptide with Multiple Mechanisms of Action, in a Murine Model of Pneumonia Induced by Methicillin-Resistant Staphylococcus aureus

Hydrophobic Vancomycin Derivatives with Improved ADME Properties: Discovery of Telavancin (TD-6424)

Plazomicin Is Active Against Metallo-β-Lactamase-Producing Enterobacteriaceae

Potent LpxC Inhibitors with In Vitro Activity against Multidrug-Resistant Pseudomonas aeruginosa

In Vitro Activities of Ceftazidime-Avibactam, Aztreonam-Avibactam, and a Panel of Older and Contemporary Antimicrobial Agents against Carbapenemase-Producing Gram-Negative Bacilli

In vitro activity of Plazomicin against Enterobacteriaceae isolates carrying genes encoding aminoglycoside-modifying enzymes most common in US Census divisions

Optimization of LpxC Inhibitors for Antibacterial Activity and Cardiovascular Safety

Pharmacodynamics of plazomicin and a comparator aminoglycoside, amikacin, studied in an in vitro pharmacokinetic model of infection

ARGONAUT II Study of the In Vitro Activity of Plazomicin against Carbapenemase-Producing Klebsiella pneumoniae

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