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1-(N-Alkylamino)-11-(N-ethylamino)-4,8-diazaundecanes: Simple Synthetic Polyamine Analogues That Differentially Alter Tubulin Polymerization

Journal of medicinal chemistry, 1999-04, Vol.42 (8), p.1415-1421

1999

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Ablation of polyamine catabolic enzymes provokes Purkinje cell damage, neuroinflammation, and severe ataxia

Journal of neuroinflammation, 2020-10, Vol.17 (1), p.301-301, Article 301

2020

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Activation of EGFR and ERBB2 by Helicobacter pylori Results in Survival of Gastric Epithelial Cells With DNA Damage

Gastroenterology (New York, N.Y. 1943), 2014-06, Vol.146 (7), p.1739-1751.e14

2014

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Acute tinnitus and hearing loss as the initial symptom of multiple sclerosis in a child

International journal of pediatric otorhinolaryngology, 2005, Vol.69 (1), p.123-126

2005

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Alkyl-Substituted Polyaminohydroxamic Acids: A Novel Class of Targeted Histone Deacetylase Inhibitors

Journal of medicinal chemistry, 2005-10, Vol.48 (20), p.6350-6365

2005

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Arginase 2 deletion leads to enhanced M1 macrophage activation and upregulated polyamine metabolism in response to Helicobacter pylori infection

Amino acids, 2016-10, Vol.48 (10), p.2375-2388

2016

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L-arginine supplementation improves responses to injury and inflammation in dextran sulfate sodium colitis

PloS one, 2012-03, Vol.7 (3), p.e33546

2012

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Autophagy induction by exogenous polyamines is an artifact of bovine serum amine oxidase activity in culture serum

The Journal of biological chemistry, 2020-07, Vol.295 (27), p.9061-9068

2020

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Biochemical evaluation of the anticancer potential of the polyamine-based nanocarrier Nano11047

PloS one, 2017-04, Vol.12 (4), p.e0175917

2017

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(Bis)urea and (Bis)thiourea Inhibitors of Lysine-Specific Demethylase 1 as Epigenetic Modulators

Journal of medicinal chemistry, 2010-07, Vol.53 (14), p.5197-5212

2010

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Characterization of a full-length cDNA which codes for the human spermidine/spermine N 1-acetyltransferase

Biochemical and biophysical research communications, 1991-08, Vol.179 (1), p.407-415

1991

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Characterizing the homeostatic regulation of the polyamine pathway using the Drosophila melanogaster model system

Gene reports, 2021-09, Vol.24, p.101269, Article 101269

2021

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Cloning and characterization of a human polyamine oxidase that is inducible by polyamine analogue exposure

Cancer research (Chicago, Ill.), 2001-07, Vol.61 (14), p.5370-5373

2001

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Cloning and Characterization of Human Polyamine-modulated Factor-1, a Transcriptional Cofactor That Regulates the Transcription of the Spermidine/Spermine N 1-Acetyltransferase Gene

The Journal of biological chemistry, 1999-07, Vol.274 (31), p.22095

1999

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Combination of Standard Cytotoxic Agents with Polyamine Analogues in the Treatment of Breast Cancer Cell Lines

Clinical cancer research, 2001-02, Vol.7 (2), p.391-399

2001

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Combination Therapy with Vidaza and Entinostat Suppresses Tumor Growth and Reprograms the Epigenome in an Orthotopic Lung Cancer Model

Cancer research (Chicago, Ill.), 2011-01, Vol.71 (2), p.454-462

2011

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Comparison of the effects of treatment with the polyamine analogue N1,N8bis(ethyl)spermidine (BESpd) or difluoromethylornithine (DFMO) on the topoisomerase II mediated formation of 4′-(9-acridinylamino) methanesulfon-m-anisidide (m-AMSA) induced cleavable complex in the human lung carcinoma line NCI H157

Biochemical and biophysical research communications, 1987-11, Vol.149 (1), p.194-202

1987

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Coupling of the polyamine and iron metabolism pathways in the regulation of proliferation: Mechanistic links to alterations in key polyamine biosynthetic and catabolic enzymes

Biochimica et biophysica acta. Molecular basis of disease, 2018-09, Vol.1864 (9), p.2793-2813

2018

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Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies

PloS one, 2018-08, Vol.13 (8), p.e0202677

2018

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Current status of the polyamine research field

Methods in molecular biology (Clifton, N.J.), 2011, Vol.720, p.3

2011

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Cyclooxygenase-independent Induction of Apoptosis by Sulindac Sulfone Is Mediated by Polyamines in Colon Cancer

The Journal of biological chemistry, 2003-11, Vol.278 (48), p.47762-47775

2003

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Cytotoxic response of the relatively difluoromethylornithine-resistant human lung tumor cell line NCI H157 to the polyamine analogue N1, N8-bis(ethyl)spermidine

Cancer research (Chicago, Ill.), 1987-08, Vol.47 (15), p.3964-3967

1987

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Deoxyhypusine synthase mutations alter the post-translational modification of eukaryotic initiation factor 5A resulting in impaired human and mouse neural homeostasis

HGG advances, 2023-07, Vol.4 (3), p.100206-100206, Article 100206

2023

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Development of a Personalized Intestinal Fibrosis Model Using Human Intestinal Organoids Derived From Induced Pluripotent Stem Cells

Inflammatory bowel diseases, 2022-05, Vol.28 (5), p.667-679

2022

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DFMO and 5-Azacytidine Increase M1 Macrophages in the Tumor Microenvironment of Murine Ovarian Cancer

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13), p.3445-3454

2019

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1-(N-Alkylamino)-11-(N-ethylamino)-4,8-diazaundecanes: Simple Synthetic Polyamine Analogues That Differentially Alter Tubulin Polymerization

Ablation of polyamine catabolic enzymes provokes Purkinje cell damage, neuroinflammation, and severe ataxia

Activation of EGFR and ERBB2 by Helicobacter pylori Results in Survival of Gastric Epithelial Cells With DNA Damage

Acute tinnitus and hearing loss as the initial symptom of multiple sclerosis in a child

Alkyl-Substituted Polyaminohydroxamic Acids: A Novel Class of Targeted Histone Deacetylase Inhibitors

Arginase 2 deletion leads to enhanced M1 macrophage activation and upregulated polyamine metabolism in response to Helicobacter pylori infection

L-arginine supplementation improves responses to injury and inflammation in dextran sulfate sodium colitis

Autophagy induction by exogenous polyamines is an artifact of bovine serum amine oxidase activity in culture serum

Biochemical evaluation of the anticancer potential of the polyamine-based nanocarrier Nano11047

(Bis)urea and (Bis)thiourea Inhibitors of Lysine-Specific Demethylase 1 as Epigenetic Modulators

Characterization of a full-length cDNA which codes for the human spermidine/spermine N 1-acetyltransferase

Characterizing the homeostatic regulation of the polyamine pathway using the Drosophila melanogaster model system

Cloning and characterization of a human polyamine oxidase that is inducible by polyamine analogue exposure

Cloning and Characterization of Human Polyamine-modulated Factor-1, a Transcriptional Cofactor That Regulates the Transcription of the Spermidine/Spermine N 1-Acetyltransferase Gene

Combination of Standard Cytotoxic Agents with Polyamine Analogues in the Treatment of Breast Cancer Cell Lines

Combination Therapy with Vidaza and Entinostat Suppresses Tumor Growth and Reprograms the Epigenome in an Orthotopic Lung Cancer Model

Coupling of the polyamine and iron metabolism pathways in the regulation of proliferation: Mechanistic links to alterations in key polyamine biosynthetic and catabolic enzymes

Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies

Current status of the polyamine research field

Cyclooxygenase-independent Induction of Apoptosis by Sulindac Sulfone Is Mediated by Polyamines in Colon Cancer

Cytotoxic response of the relatively difluoromethylornithine-resistant human lung tumor cell line NCI H157 to the polyamine analogue N1, N8-bis(ethyl)spermidine

Deoxyhypusine synthase mutations alter the post-translational modification of eukaryotic initiation factor 5A resulting in impaired human and mouse neural homeostasis

Development of a Personalized Intestinal Fibrosis Model Using Human Intestinal Organoids Derived From Induced Pluripotent Stem Cells

DFMO and 5-Azacytidine Increase M1 Macrophages in the Tumor Microenvironment of Murine Ovarian Cancer

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