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Protease-activated receptor 2 activation induces behavioural changes associated with depression-like behaviour through microglial-independent modulation of inflammatory cytokines

Psychopharmacology, 2022-01, Vol.239 (1), p.229-242

2022

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PAR2 activation in the dura causes acute behavioral responses and priming to glyceryl trinitrate in a mouse migraine model

Journal of headache and pain, 2023-04, Vol.24 (1), p.42-42, Article 42

2023

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Interaction of Mite Allergens Der P3 and Der P9 with Protease-Activated Receptor-2 Expressed by Lung Epithelial Cells

The Journal of immunology (1950), 2001-07, Vol.167 (2), p.1014-1021

2001

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Proteinase-Activated Receptor 2 is an Anti-Inflammatory Signal for Colonic Lamina Propria Lymphocytes in a Mouse Model of Colitis

Proceedings of the National Academy of Sciences - PNAS, 2001-11, Vol.98 (24), p.13936-13941

2001

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Trypsin Induces Activation and Inflammatory Mediator Release from Human Eosinophils Through Protease-Activated Receptor-2

The Journal of immunology (1950), 2001-12, Vol.167 (11), p.6615-6622

2001

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Signalling pathways induced by protease‐activated receptors and integrins in T cells

Immunology, 2002-01, Vol.105 (1), p.35-46

2002

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Upregulation of Protease-Activated Receptor 2 Promotes Proliferation and Migration of Human Vascular Smooth Muscle Cells (VSMCs)

Medical science monitor, 2019-11, Vol.25, p.8854-8862

2019

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PARting Neuroinflammation with Protease-Activated Receptor 2 Pepducins

The Journal of pharmacology and experimental therapeutics, 2024-01, Vol.388 (1), p.8-11

Scarisbrick, Isobel A

2024

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Protease-activated receptor 2 induces ROS-mediated inflammation through Akt-mediated NF-κB and FoxO6 modulation during skin photoaging

Redox biology, 2021-08, Vol.44, p.102022-102022, Article 102022

2021

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PAR2 induces ovarian cancer cell motility by merging three signalling pathways to transactivate EGFR

British journal of pharmacology, 2021-02, Vol.178 (4), p.913-932

2021

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Protease-Activated Receptor-2 Decreased Zonula Occlidens-1 and Claudin-1 Expression and Induced Epithelial Barrier Dysfunction in Allergic Rhinitis

American journal of rhinology & allergy, 2021-01, Vol.35 (1), p.26-35

2021

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Mast Cell Tryptase Promotes Inflammatory Bowel Disease–Induced Intestinal Fibrosis

Inflammatory bowel diseases, 2021-02, Vol.27 (2), p.242-255

2021

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Human neutrophil elastase induces endothelial cell apoptosis by activating the PERK‐CHOP branch of the unfolded protein response

The FASEB journal, 2017-09, Vol.31 (9), p.3868-3881

2017

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The protease activated receptor 2 - CCAAT/enhancer-binding protein beta - SerpinB3 axis inhibition as a novel strategy for the treatment of non-alcoholic steatohepatitis

Molecular metabolism (Germany), 2024-03, Vol.81, p.101889-101889, Article 101889

2024

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TRPV3 Channel in Keratinocytes in Scars with Post-Burn Pruritus

International journal of molecular sciences, 2017-11, Vol.18 (11), p.2425

2017

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Activation of Endothelial Cell Protease Activated Receptor 1 by the Protein C Pathway

Science (American Association for the Advancement of Science), 2002-06, Vol.296 (5574), p.1880-1882

2002

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Transcriptional regulation of IL-17A and other inflammatory markers during the development of soybean meal-induced enteropathy in the distal intestine of Atlantic salmon (Salmo salar L.)

Cytokine (Philadelphia, Pa.), 2012-10, Vol.60 (1), p.186-196

2012

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FSLLRY-NH 2 , a protease-activated receptor 2 (PAR2) antagonist, activates mas-related G protein-coupled receptor C11 (MrgprC11) to induce scratching behaviors in mice

Life sciences (1973), 2023-07, Vol.325, p.121786

2023

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Polarization of the C. elegans zygote proceeds via distinct establishment and maintenance phases

Development (Cambridge), 2003-04, Vol.130 (7), p.1255-1265

2003

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PARticipation in inflammation

The Journal of clinical investigation, 2003-01, Vol.111 (1), p.25-27

2003

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β-Arrestin-Dependent Endocytosis of Proteinase-Activated Receptor 2 Is Required for Intracellular Targeting of Activated ERK1/2

The Journal of cell biology, 2000-03, Vol.148 (6), p.1267-1281

2000

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House Dust Mite Allergens Induce Proinflammatory Cytokines from Respiratory Epithelial Cells: The Cysteine Protease Allergen, Der p 1, Activates Protease-Activated Receptor (PAR)-2 and Inactivates PAR-1

The Journal of immunology (1950), 2002-10, Vol.169 (8), p.4572-4578

2002

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The Role of Protease-Activated Receptor 2 in Hepatocellular Carcinoma after Hepatectomy

Medicina (Kaunas, Lithuania), 2021-06, Vol.57 (6), p.574

2021

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Histone 2B Facilitates Plasminogen-Enhanced Endothelial Migration through Protease-Activated Receptor 1 (PAR1) and Protease-Activated Receptor 2 (PAR2)

Biomolecules (Basel, Switzerland), 2022-01, Vol.12 (2), p.211

2022

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Proteinase-activated receptors: novel mechanisms of signaling by serine proteases

American Journal of Physiology: Cell Physiology, 1998-06, Vol.274 (6), p.C1429-C1452

1998

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Protease-activated receptor 2 activation induces behavioural changes associated with depression-like behaviour through microglial-independent modulation of inflammatory cytokines

PAR2 activation in the dura causes acute behavioral responses and priming to glyceryl trinitrate in a mouse migraine model

Interaction of Mite Allergens Der P3 and Der P9 with Protease-Activated Receptor-2 Expressed by Lung Epithelial Cells

Proteinase-Activated Receptor 2 is an Anti-Inflammatory Signal for Colonic Lamina Propria Lymphocytes in a Mouse Model of Colitis

Trypsin Induces Activation and Inflammatory Mediator Release from Human Eosinophils Through Protease-Activated Receptor-2

Signalling pathways induced by protease‐activated receptors and integrins in T cells

Upregulation of Protease-Activated Receptor 2 Promotes Proliferation and Migration of Human Vascular Smooth Muscle Cells (VSMCs)

PARting Neuroinflammation with Protease-Activated Receptor 2 Pepducins

Protease-activated receptor 2 induces ROS-mediated inflammation through Akt-mediated NF-κB and FoxO6 modulation during skin photoaging

PAR2 induces ovarian cancer cell motility by merging three signalling pathways to transactivate EGFR

Protease-Activated Receptor-2 Decreased Zonula Occlidens-1 and Claudin-1 Expression and Induced Epithelial Barrier Dysfunction in Allergic Rhinitis

Mast Cell Tryptase Promotes Inflammatory Bowel Disease–Induced Intestinal Fibrosis

Human neutrophil elastase induces endothelial cell apoptosis by activating the PERK‐CHOP branch of the unfolded protein response

The protease activated receptor 2 - CCAAT/enhancer-binding protein beta - SerpinB3 axis inhibition as a novel strategy for the treatment of non-alcoholic steatohepatitis

TRPV3 Channel in Keratinocytes in Scars with Post-Burn Pruritus

Activation of Endothelial Cell Protease Activated Receptor 1 by the Protein C Pathway

Transcriptional regulation of IL-17A and other inflammatory markers during the development of soybean meal-induced enteropathy in the distal intestine of Atlantic salmon (Salmo salar L.)

FSLLRY-NH 2 , a protease-activated receptor 2 (PAR2) antagonist, activates mas-related G protein-coupled receptor C11 (MrgprC11) to induce scratching behaviors in mice

Polarization of the C. elegans zygote proceeds via distinct establishment and maintenance phases

PARticipation in inflammation

β-Arrestin-Dependent Endocytosis of Proteinase-Activated Receptor 2 Is Required for Intracellular Targeting of Activated ERK1/2

House Dust Mite Allergens Induce Proinflammatory Cytokines from Respiratory Epithelial Cells: The Cysteine Protease Allergen, Der p 1, Activates Protease-Activated Receptor (PAR)-2 and Inactivates PAR-1

The Role of Protease-Activated Receptor 2 in Hepatocellular Carcinoma after Hepatectomy

Histone 2B Facilitates Plasminogen-Enhanced Endothelial Migration through Protease-Activated Receptor 1 (PAR1) and Protease-Activated Receptor 2 (PAR2)

Proteinase-activated receptors: novel mechanisms of signaling by serine proteases

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