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UDP‐Glucuronosyltransferase (UGT)‐mediated attenuations of cytochrome P450 3A4 activity: UGT isoform‐dependent mechanism of suppression

British journal of pharmacology, 2020-03, Vol.177 (5), p.1077-1089

2020

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The aryl hydrocarbon receptor is indispensable for dioxin-induced defects in sexually-dimorphic behaviors due to the reduction in fetal steroidogenesis of the pituitary-gonadal axis in rats

Biochemical pharmacology, 2018-08, Vol.154, p.213-221

2018

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Dioxin-induced increase in leukotriene B4 biosynthesis through the aryl hydrocarbon receptor and its relevance to hepatotoxicity owing to neutrophil infiltration

The Journal of biological chemistry, 2017-06, Vol.292 (25), p.10586-10599

2017

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Maternal exposure to dioxin imprints sexual immaturity of the pups through fixing the status of the reduced expression of hypothalamic gonadotropin-releasing hormone

Molecular pharmacology, 2014-01, Vol.85 (1), p.74-82

2014

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Restoration of dioxin-induced damage to fetal steroidogenesis and gonadotropin formation by maternal co-treatment with α-lipoic acid

PloS one, 2012-07, Vol.7 (7), p.e40322

2012

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Inhibition of Morphine Glucuronidation in the Liver Microsomes of Rats and Humans by Monoterpenoid Alcohols

Biological and Pharmaceutical Bulletin, 2012/10/01, Vol.35(10), pp.1811-1817

2012

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Dioxin-induced fetal growth retardation: the role of a preceding attenuation in the circulating level of glucocorticoid

Endocrine, 2014-11, Vol.47 (2), p.572-580

2014

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α-Lipoic acid potentially targets AMP-activated protein kinase and energy production in the fetal brain to ameliorate dioxin-produced attenuation in fetal steroidogenesis

The Journal of Toxicological Sciences, 2017/02/01, Vol.42(1), pp.13-23

2017

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Effect of in utero exposure to endocrine disruptors on fetal steroidogenesis governed by the pituitary-gonad axis: a study in rats using different ways of administration

The Journal of Toxicological Sciences, 2015/12/01, Vol.40(6), pp.909-916

2015

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2,3,4,7,8-Pentachlorodibenzofuran is far less potent than 2,3,7,8-tetrachlorodibenzo-p-dioxin in disrupting the pituitary–gonad axis of the rat fetus

Toxicology and applied pharmacology, 2014-11, Vol.281 (1), p.48-57

2014

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Maternal exposure to dioxin disrupts gonadotropin production in fetal rats and imprints defects in sexual behavior

The Journal of pharmacology and experimental therapeutics, 2009-06, Vol.329 (3), p.1091-1099

2009

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Interaction of Cytochrome P450 3A4 and UDP-Glucuronosyltransferase 2B7: Evidence for Protein-Protein Association and Possible Involvement of CYP3A4 J-Helix in the Interaction

Molecular pharmacology, 2009-04, Vol.75 (4), p.956-964

2009

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Development of a novel serum-free freezing medium for mammalian cells using the silk protein sericin

Biotechnology and applied biochemistry, 2005-10, Vol.42 (2), p.183-188

2005

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Hypoxia-induced retinal ganglion cell death and the neuroprotective effects of beta-adrenergic antagonists

Brain research, 2007-05, Vol.1148, p.28-37

2007

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Fetal Pituitary Gonadotropin as an Initial Target of Dioxin in Its Impairment of Cholesterol Transportation and Steroidogenesis in Rats

Endocrinology (Philadelphia), 2006-02, Vol.147 (2), p.927-936

2006

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Protein-Protein Interactions between Rat Hepatic Cytochromes P450 (P450s) and UDP-Glucuronosyltransferases (UGTs): Evidence for the Functionally Active UGT in P450-UGT Complex

DRUG METABOLISM AND PHARMACOKINETICS, 2007-01, Vol.22 (5), p.367-376

2007

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Neuroprotective effect of calcium channel blocker against retinal ganglion cell damage under hypoxia

Brain research, 2006-02, Vol.1071 (1), p.75-80

2006

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Silk protein, sericin, inhibits lipid peroxidation and tyrosinase activity

Bioscience, biotechnology, and biochemistry, 1998-01, Vol.62 (1), p.145-147

1998

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Maternal exposure to dioxin reduces hypothalamic but not pituitary metabolome in fetal rats: a possible mechanism for a fetus-specific reduction in steroidogenesis

The Journal of Toxicological Sciences, 2010/06/01, Vol.35(3), pp.365-373

2010

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Activation of Morphine Glucuronidation by Fatty Acyl-CoAs and Its Plasticity: A Comparative Study in Humans and Rodents Including Chimeric Mice Carrying Human Liver

DRUG METABOLISM AND PHARMACOKINETICS, 2010-01, Vol.25 (3), p.262-273

2010

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Suppression of fetal testicular cytochrome P450 17 by maternal exposure to 2,3,7,8-tetrachlorodibenzo- p-dioxin: A mechanism involving an initial effect on gonadotropin synthesis in the pituitary

Life sciences (1973), 2007-03, Vol.80 (14), p.1259-1267

2007

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2,3,7,8-Tetrachlorodibenzo-p-dioxin potentially attenuates the gene expression of pituitary gonadotropin β-subunits in a fetal age-specific fashion: a comparative study using cultured pituitaries

The Journal of Toxicological Sciences, 2011/04/01, Vol.36(2), pp.221-229

2011

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Inhibitory effects of adenine nucleotides and related substances on UDP-glucuronosyltransferase: Structure–effect relationships and evidence for an allosteric mechanism

Biochimica et biophysica acta, 2007-11, Vol.1770 (11), p.1557-1566

2007

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Gestational dioxin exposure suppresses prolactin-stimulated nursing in lactating dam rats to impair development of postnatal offspring

Biochemical pharmacology, 2020-08, Vol.178, p.114106, Article 114106

2020

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Distribution of 14C-2,3,7,8-tetrachlorodibenzo-p-dioxin to the brain and peripheral tissues of fetal rats and its comparison with adults

The Journal of Toxicological Sciences, 2010/08/01, Vol.35(4), pp.563-569

2010

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UDP‐Glucuronosyltransferase (UGT)‐mediated attenuations of cytochrome P450 3A4 activity: UGT isoform‐dependent mechanism of suppression

The aryl hydrocarbon receptor is indispensable for dioxin-induced defects in sexually-dimorphic behaviors due to the reduction in fetal steroidogenesis of the pituitary-gonadal axis in rats

Dioxin-induced increase in leukotriene B4 biosynthesis through the aryl hydrocarbon receptor and its relevance to hepatotoxicity owing to neutrophil infiltration

Maternal exposure to dioxin imprints sexual immaturity of the pups through fixing the status of the reduced expression of hypothalamic gonadotropin-releasing hormone

Restoration of dioxin-induced damage to fetal steroidogenesis and gonadotropin formation by maternal co-treatment with α-lipoic acid

Inhibition of Morphine Glucuronidation in the Liver Microsomes of Rats and Humans by Monoterpenoid Alcohols

Dioxin-induced fetal growth retardation: the role of a preceding attenuation in the circulating level of glucocorticoid

α-Lipoic acid potentially targets AMP-activated protein kinase and energy production in the fetal brain to ameliorate dioxin-produced attenuation in fetal steroidogenesis

Effect of in utero exposure to endocrine disruptors on fetal steroidogenesis governed by the pituitary-gonad axis: a study in rats using different ways of administration

2,3,4,7,8-Pentachlorodibenzofuran is far less potent than 2,3,7,8-tetrachlorodibenzo-p-dioxin in disrupting the pituitary–gonad axis of the rat fetus

Maternal exposure to dioxin disrupts gonadotropin production in fetal rats and imprints defects in sexual behavior

Interaction of Cytochrome P450 3A4 and UDP-Glucuronosyltransferase 2B7: Evidence for Protein-Protein Association and Possible Involvement of CYP3A4 J-Helix in the Interaction

Development of a novel serum-free freezing medium for mammalian cells using the silk protein sericin

Hypoxia-induced retinal ganglion cell death and the neuroprotective effects of beta-adrenergic antagonists

Fetal Pituitary Gonadotropin as an Initial Target of Dioxin in Its Impairment of Cholesterol Transportation and Steroidogenesis in Rats

Protein-Protein Interactions between Rat Hepatic Cytochromes P450 (P450s) and UDP-Glucuronosyltransferases (UGTs): Evidence for the Functionally Active UGT in P450-UGT Complex

Neuroprotective effect of calcium channel blocker against retinal ganglion cell damage under hypoxia

Silk protein, sericin, inhibits lipid peroxidation and tyrosinase activity

Maternal exposure to dioxin reduces hypothalamic but not pituitary metabolome in fetal rats: a possible mechanism for a fetus-specific reduction in steroidogenesis

Activation of Morphine Glucuronidation by Fatty Acyl-CoAs and Its Plasticity: A Comparative Study in Humans and Rodents Including Chimeric Mice Carrying Human Liver

Suppression of fetal testicular cytochrome P450 17 by maternal exposure to 2,3,7,8-tetrachlorodibenzo- p-dioxin: A mechanism involving an initial effect on gonadotropin synthesis in the pituitary

2,3,7,8-Tetrachlorodibenzo-p-dioxin potentially attenuates the gene expression of pituitary gonadotropin β-subunits in a fetal age-specific fashion: a comparative study using cultured pituitaries

Inhibitory effects of adenine nucleotides and related substances on UDP-glucuronosyltransferase: Structure–effect relationships and evidence for an allosteric mechanism

Gestational dioxin exposure suppresses prolactin-stimulated nursing in lactating dam rats to impair development of postnatal offspring

Distribution of 14C-2,3,7,8-tetrachlorodibenzo-p-dioxin to the brain and peripheral tissues of fetal rats and its comparison with adults

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