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Translation of curative therapy concepts with T cell and cytokine antibody combinations for type 1 diabetes reversal in the IDDM rat

Journal of molecular medicine (Berlin, Germany), 2020-08, Vol.98 (8), p.1125-1137

2020

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Immune Cell Infiltration, Cytokine Expression, and β-Cell Apoptosis During the Development of Type 1 Diabetes in the Spontaneously Diabetic LEW.1AR1/Ztm-iddm Rat

Diabetes (New York, N.Y.), 2005-07, Vol.54 (7), p.2041-2052

2005

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Glucokinase mediates coupling of glycolysis to mitochondrial metabolism but not to beta cell damage at high glucose exposure levels

Diabetologia, 2011-07, Vol.54 (7), p.1744-1755

2011

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Variable immune cell frequencies in peripheral blood of LEW.1AR1‐iddm rats over time compared to other congenic LEW strains

Clinical and experimental immunology, 2014-07, Vol.177 (1), p.168-178

2014

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The LEW.1AR1/Ztm-iddm rat : a new model of spontaneous insulin-dependent diabetes mellitus

Diabetologia, 2001-09, Vol.44 (9), p.1189-1196

2001

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Impaired Glucose-Stimulated Insulin Secretion Is Coupled With Exocrine Pancreatic Lesions in the Cohen Diabetic Rat

Diabetes (New York, N.Y.), 2008-02, Vol.57 (2), p.279-287

2008

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Improved antioxidative defence protects insulin-producing cells against homocysteine toxicity

Chemico-biological interactions, 2016-08, Vol.256 (C), p.37-46

2016

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Prevention of spontaneous immune-mediated diabetes development in the LEW.1AR1-iddm rat by selective CD8⁺ T cell transfer is associated with a cytokine shift in the pancreas-draining lymph nodes

Diabetologia, 2009-07, Vol.52 (7), p.1381-1390

2009

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The Ras Mutant D119N Is Both Dominant Negative and Activated

Molecular and Cellular Biology, 1999-09, Vol.19 (9), p.6297-6305

1999

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Metabolic regulation, activity state, and intracellular binding of glucokinase in insulin-secreting cells

Diabetes (New York, N.Y.), 1999-03, Vol.48 (3), p.514

1999

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Engineering of a glucose-responsive surrogate cell for insulin replacement therapy of experimental insulin-dependent diabetes

Human gene therapy, 2000-02, Vol.11 (3), p.403-414

2000

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Genetic analysis of the LEW.1AR1-iddm rat: an animal model for spontaneous diabetes mellitus

Mammalian genome, 2005-06, Vol.16 (6), p.432-441

2005

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Pathology of the pancreas and other organs in the diabetic LEW.1AR1/Ztm-iddm rat, a new model of spontaneous insulin-dependent diabetes mellitus

Virchows Archiv : an international journal of pathology, 2004-02, Vol.444 (2), p.183-189

2004

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Effects of polyinosinic-polycytidylic acid and adoptive transfer of immune cells in the LEW.1AR1-iddm rat and in its coisogenic LEW.1AR1 background strain

Autoimmunity (Chur, Switzerland), 2005-06, Vol.38 (4), p.265-275

2005

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Polyamine modulation of mitochondrial calcium transport: I. stimulatory and inhibitory effects of aliphatic polyamines, aminoglucosides and other polyamine analogues on mitochondrial calcium uptake

Biochemical pharmacology, 1998-10, Vol.56 (8), p.977-985

1998

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Polyamine modulation of mitochondrial calcium transport: II. inhibition of mitochondrial permeability transition by aliphatic polyamines but not by aminoglucosides

Biochemical pharmacology, 1998-10, Vol.56 (8), p.987-995

1998

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Molecular Characterization of the Glucose-Sensing Mechanism in the Clonal Insulin-Secreting BRIN-BD11 Cell Line

Biochemical and biophysical research communications, 1998-01, Vol.242 (2), p.262-266

1998

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Histogenesis of bile duct-like cells proliferating during ethionine hepatocarcinogenesis. Evidence for a biliary epithelial nature of oval cells

Laboratory investigation, 1992-03, Vol.66 (3), p.390

1992

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Structural requirements of alloxan and ninhydrin for glucokinase inhibition and of glucose for protection against inhibition

British journal of pharmacology, 1988-11, Vol.95 (3), p.851-859

1988

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Increase in hepatic mixed disulphide and glutathione disulphide levels elicited by paraquat

Biochemical pharmacology, 1982-04, Vol.31 (8), p.1637-1641

1982

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Structural requirements of lysophospholipid-regulated mitochondrial Ca2+ transport

Biochimica et biophysica acta, 1991-10, Vol.1069 (1), p.99-109

1991

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Cholestasis and changes in the microcirculation of perfused rat liver caused by the calcium ionophore A23187 and type I antiarrhythmic drugs

Biochemical pharmacology, 1987-09, Vol.36 (18), p.3037-3042

1987

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Effects of alloxan and ninhydrin on mitochondrial Ca2+ transport

Molecular and cellular biochemistry, 1992-12, Vol.118 (2), p.141-151

1992

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Inhibition of insulin secretion by L-thyroxine and D-thyroxine treatment in rats under the influence of drugs affecting the adrenergic nervous system

Acta endocrinologica (Copenhagen), 1982-08, Vol.100 (4), p.527

1982

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Monoamine oxidase in pancreatic islets, exocrine pancreas, and liver from rats. Characterization with clorgyline, deprenyl, pargyline, tranylcypromine, and amezinium

Naunyn-Schmiedeberg's archives of pharmacology, 1983-11, Vol.324 (3), p.190-195

1983

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Translation of curative therapy concepts with T cell and cytokine antibody combinations for type 1 diabetes reversal in the IDDM rat

Immune Cell Infiltration, Cytokine Expression, and β-Cell Apoptosis During the Development of Type 1 Diabetes in the Spontaneously Diabetic LEW.1AR1/Ztm-iddm Rat

Glucokinase mediates coupling of glycolysis to mitochondrial metabolism but not to beta cell damage at high glucose exposure levels

Variable immune cell frequencies in peripheral blood of LEW.1AR1‐iddm rats over time compared to other congenic LEW strains

The LEW.1AR1/Ztm-iddm rat : a new model of spontaneous insulin-dependent diabetes mellitus

Impaired Glucose-Stimulated Insulin Secretion Is Coupled With Exocrine Pancreatic Lesions in the Cohen Diabetic Rat

Improved antioxidative defence protects insulin-producing cells against homocysteine toxicity

Prevention of spontaneous immune-mediated diabetes development in the LEW.1AR1-iddm rat by selective CD8⁺ T cell transfer is associated with a cytokine shift in the pancreas-draining lymph nodes

The Ras Mutant D119N Is Both Dominant Negative and Activated

Metabolic regulation, activity state, and intracellular binding of glucokinase in insulin-secreting cells

Engineering of a glucose-responsive surrogate cell for insulin replacement therapy of experimental insulin-dependent diabetes

Genetic analysis of the LEW.1AR1-iddm rat: an animal model for spontaneous diabetes mellitus

Pathology of the pancreas and other organs in the diabetic LEW.1AR1/Ztm-iddm rat, a new model of spontaneous insulin-dependent diabetes mellitus

Effects of polyinosinic-polycytidylic acid and adoptive transfer of immune cells in the LEW.1AR1-iddm rat and in its coisogenic LEW.1AR1 background strain

Polyamine modulation of mitochondrial calcium transport: I. stimulatory and inhibitory effects of aliphatic polyamines, aminoglucosides and other polyamine analogues on mitochondrial calcium uptake

Polyamine modulation of mitochondrial calcium transport: II. inhibition of mitochondrial permeability transition by aliphatic polyamines but not by aminoglucosides

Molecular Characterization of the Glucose-Sensing Mechanism in the Clonal Insulin-Secreting BRIN-BD11 Cell Line

Histogenesis of bile duct-like cells proliferating during ethionine hepatocarcinogenesis. Evidence for a biliary epithelial nature of oval cells

Structural requirements of alloxan and ninhydrin for glucokinase inhibition and of glucose for protection against inhibition

Increase in hepatic mixed disulphide and glutathione disulphide levels elicited by paraquat

Structural requirements of lysophospholipid-regulated mitochondrial Ca2+ transport

Cholestasis and changes in the microcirculation of perfused rat liver caused by the calcium ionophore A23187 and type I antiarrhythmic drugs

Effects of alloxan and ninhydrin on mitochondrial Ca2+ transport

Inhibition of insulin secretion by L-thyroxine and D-thyroxine treatment in rats under the influence of drugs affecting the adrenergic nervous system

Monoamine oxidase in pancreatic islets, exocrine pancreas, and liver from rats. Characterization with clorgyline, deprenyl, pargyline, tranylcypromine, and amezinium

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