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Bromuconazole-induced hepatotoxicity is accompanied by upregulation of PXR/CYP3A1 and downregulation of CAR/CYP2B1 gene expression

Toxicology mechanisms and methods, 2017-09, Vol.27 (7), p.544-550

2017

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Biologically relevant reductions in fetal testosterone and Insl3 induced by in utero exposure to high levels of di-isononyl phthalate (DINP) in male rats

Toxicology and applied pharmacology, 2023-04, Vol.465, p.116454-116454, Article 116454

Earl Gray, L.

2023

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Developmental triclosan exposure decreases maternal, fetal, and early neonatal thyroxine: A dynamic and kinetic evaluation of a putative mode-of-action

Toxicology (Amsterdam), 2012-10, Vol.300 (1-2), p.31-45

2012

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Inhibitory effects of a dietary phytochemical 3,3′-diindolylmethane on the phenobarbital-induced hepatic CYP mRNA expression and CYP-catalyzed reactions in female rats

Food and chemical toxicology, 2008-07, Vol.46 (7), p.2451-2458

2008

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Identification of 17-α-Ethynylestradiol-Modified Active Site Peptides and Glutathione Conjugates Formed during Metabolism and Inactivation of P450s 2B1 and 2B6

Chemical research in toxicology, 2006-02, Vol.19 (2), p.279-287

2006

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Sex differences in subacute toxicity and hepatic microsomal metabolism of triptolide in rats

Toxicology (Amsterdam), 2010-04, Vol.271 (1), p.57-63

2010

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Mechanism-Based Inactivation of Human Cytochrome P450 2B6 by Chlorpyrifos

Chemical research in toxicology, 2015-07, Vol.28 (7), p.1484-1495

2015

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Proteasome-dependent degradation of cytochromes P450 2E1 and 2B1 expressed in tetracycline-regulated HeLa cells

Toxicology and applied pharmacology, 2004-09, Vol.199 (3), p.332-343

2004

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Age-related changes in hepatic expression and activity of cytochrome P450 in male rats

Archives of toxicology, 2010-12, Vol.84 (12), p.939-946

2010

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Role for mitogen-activated protein kinases in phenobarbital-induced expression of cytochrome P450 2B in primary cultures of rat hepatocytes

Toxicology letters, 2006-02, Vol.161 (1), p.61-72

2006

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Differential Expression of CYP1A, 2B, and 3A Genes in the F344 Rat following Exposure to a Polybrominated Diphenyl Ether Mixture or Individual Components

Toxicological sciences, 2005-11, Vol.88 (1), p.127-133

2005

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Effects of Sublethal Exposure to a Glyphosate-Based Herbicide Formulation on Metabolic Activities of Different Xenobiotic-Metabolizing Enzymes in Rats

International journal of toxicology, 2014-07, Vol.33 (4), p.307-318

2014

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Effects of short-term in vivo exposure to polybrominated diphenyl ethers on thyroid hormones and hepatic enzyme activities in weanling rats

Toxicological sciences, 2001-05, Vol.61 (1), p.76-82

2001

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CAR expression and inducibility of CYP2B genes in liver of rats treated with PB-like inducers

Toxicology (Amsterdam), 2005-12, Vol.216 (2), p.147-153

2005

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A technical mixture of 2,2′,4,4′-tetrabromo diphenyl ether (BDE47) and brominated furans triggers aryl hydrocarbon receptor (AhR) mediated gene expression and toxicity

Chemosphere (Oxford), 2008-09, Vol.73 (2), p.209-215

2008

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Mode of Action Analysis for the Synthetic Pyrethroid Metofluthrin-Induced Rat Liver Tumors: Evidence for Hepatic CYP2B Induction and Hepatocyte Proliferation

Toxicological sciences, 2009-03, Vol.108 (1), p.69-80

2009

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Induction of CYP2B1/2 and nicotine metabolism by ethanol in rat liver but not rat brain

Biochemical pharmacology, 2001-10, Vol.62 (8), p.1025-1036

2001

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Effect of naturally occurring plant phenolics on the induction of drug metabolizing enzymes by o-toluidine

Toxicology (Amsterdam), 2003-04, Vol.186 (1), p.67-77

2003

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Changes in expression of hepatic cytochrome P450 subfamily enzymes during development of adjuvant-induced arthritis in rats

The Journal of Toxicological Sciences, 2011/04/01, Vol.36(2), pp.181-190

2011

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N-Nitrosodiethylamine genotoxicity in primary rat hepatocytes: Effects of cytochrome P450 induction by phenobarbital

Toxicology letters, 2011-10, Vol.206 (2), p.139-143

2011

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Different profiles of hepatic alkoxyresorufin O-dealkylase activities in small rodents

Journal of applied toxicology, 2012-12, Vol.32 (12), p.1002-1007

2012

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The enhancing effect of ethanol on the mutagenic activation of N-nitrosomethylbenzylamine by cytochrome P450 2A in the rat oesophagus

Mutagenesis, 2013-03, Vol.28 (2), p.161-169

2013

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In vitro metabolism and covalent binding of ethylbenzene to microsomal protein as a possible mechanism of ethylbenzene-induced mouse lung tumorigenesis

Regulatory toxicology and pharmacology, 2010-07, Vol.57 (2-3), p.129-135

2010

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Green tea extract increases cyclophosphamide-induced teratogenesis by modulating the expression of cytochrome P-450 mRNA

Reproductive toxicology (Elmsford, N.Y.), 2009, Vol.27 (1), p.79-84

2009

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Cancer Prevention Mediated by Caffeic Acid Phenethyl Ester Involves Cyp2b1/2 Modulation in Hepatocarcinogenesis

Toxicologic pathology, 2012-04, Vol.40 (3), p.466-472

2012

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Bromuconazole-induced hepatotoxicity is accompanied by upregulation of PXR/CYP3A1 and downregulation of CAR/CYP2B1 gene expression

Biologically relevant reductions in fetal testosterone and Insl3 induced by in utero exposure to high levels of di-isononyl phthalate (DINP) in male rats

Developmental triclosan exposure decreases maternal, fetal, and early neonatal thyroxine: A dynamic and kinetic evaluation of a putative mode-of-action

Inhibitory effects of a dietary phytochemical 3,3′-diindolylmethane on the phenobarbital-induced hepatic CYP mRNA expression and CYP-catalyzed reactions in female rats

Identification of 17-α-Ethynylestradiol-Modified Active Site Peptides and Glutathione Conjugates Formed during Metabolism and Inactivation of P450s 2B1 and 2B6

Sex differences in subacute toxicity and hepatic microsomal metabolism of triptolide in rats

Mechanism-Based Inactivation of Human Cytochrome P450 2B6 by Chlorpyrifos

Proteasome-dependent degradation of cytochromes P450 2E1 and 2B1 expressed in tetracycline-regulated HeLa cells

Age-related changes in hepatic expression and activity of cytochrome P450 in male rats

Role for mitogen-activated protein kinases in phenobarbital-induced expression of cytochrome P450 2B in primary cultures of rat hepatocytes

Differential Expression of CYP1A, 2B, and 3A Genes in the F344 Rat following Exposure to a Polybrominated Diphenyl Ether Mixture or Individual Components

Effects of Sublethal Exposure to a Glyphosate-Based Herbicide Formulation on Metabolic Activities of Different Xenobiotic-Metabolizing Enzymes in Rats

Effects of short-term in vivo exposure to polybrominated diphenyl ethers on thyroid hormones and hepatic enzyme activities in weanling rats

CAR expression and inducibility of CYP2B genes in liver of rats treated with PB-like inducers

A technical mixture of 2,2′,4,4′-tetrabromo diphenyl ether (BDE47) and brominated furans triggers aryl hydrocarbon receptor (AhR) mediated gene expression and toxicity

Mode of Action Analysis for the Synthetic Pyrethroid Metofluthrin-Induced Rat Liver Tumors: Evidence for Hepatic CYP2B Induction and Hepatocyte Proliferation

Induction of CYP2B1/2 and nicotine metabolism by ethanol in rat liver but not rat brain

Effect of naturally occurring plant phenolics on the induction of drug metabolizing enzymes by o-toluidine

Changes in expression of hepatic cytochrome P450 subfamily enzymes during development of adjuvant-induced arthritis in rats

N-Nitrosodiethylamine genotoxicity in primary rat hepatocytes: Effects of cytochrome P450 induction by phenobarbital

Different profiles of hepatic alkoxyresorufin O-dealkylase activities in small rodents

The enhancing effect of ethanol on the mutagenic activation of N-nitrosomethylbenzylamine by cytochrome P450 2A in the rat oesophagus

In vitro metabolism and covalent binding of ethylbenzene to microsomal protein as a possible mechanism of ethylbenzene-induced mouse lung tumorigenesis

Green tea extract increases cyclophosphamide-induced teratogenesis by modulating the expression of cytochrome P-450 mRNA

Cancer Prevention Mediated by Caffeic Acid Phenethyl Ester Involves Cyp2b1/2 Modulation in Hepatocarcinogenesis

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