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Induction of OTUD1 by RNA viruses potently inhibits innate immune responses by promoting degradation of the MAVS/TRAF3/TRAF6 signalosome

PLoS pathogens, 2018-05, Vol.14 (5), p.e1007067-e1007067

2018

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USP27X negatively regulates antiviral signaling by deubiquitinating RIG-I

PLoS pathogens, 2020-02, Vol.16 (2), p.e1008293-e1008293

2020

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Ubiquitin specific peptidase 4 stabilizes interferon regulatory factor protein and promotes its function to facilitate interleukin-4 expression in T helper type 2 cells

International journal of molecular medicine, 2017-10, Vol.40 (4), p.979-986

2017

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A putative OTU domain-containing protein 1 deubiquitinating enzyme is differentially expressed in thyroid cancer and identifies less-aggressive tumours

British journal of cancer, 2014-07, Vol.111 (3), p.551-558

2014

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Monoclonal Antibody Specific for Ovarian Tumor Domain-Containing Protein 1

Monoclonal antibodies in immunodiagnosis and immunotherapy, 2018-08, Vol.37 (4), p.194-194

2018

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Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60

PloS one, 2017-12, Vol.12 (12), p.e0189744-e0189744

2017

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Induction of OTUD4 by viral infection promotes antiviral responses through deubiquitinating and stabilizing MAVS

Cell research, 2019-01, Vol.29 (1), p.67-79

2019

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Cancer cell-derived exosomal circUSP7 induces CD8 + T cell dysfunction and anti-PD1 resistance by regulating the miR-934/SHP2 axis in NSCLC

Molecular cancer, 2021-11, Vol.20 (1), p.144-144, Article 144

2021

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USP13 negatively regulates antiviral responses by deubiquitinating STING

Nature communications, 2017-05, Vol.8 (1), p.15534-15534, Article 15534

2017

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USP15: a review of its implication in immune and inflammatory processes and tumor progression

Genes and immunity, 2021-05, Vol.22 (1), p.12-23

2021

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The deubiquitinase OTUD1 enhances iron transport and potentiates host antitumor immunity

EMBO reports, 2021-02, Vol.22 (2), p.e51162-n/a

2021

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Ubiquitin-Specific Protease 43 Impacts Pancreatic Ductal Adenocarcinoma Prognosis by Altering Its Proliferation and Infiltration of Surrounding Immune Cells

Journal of Immunology Research, 2023-04, Vol.2023, p.4311388-13

2023

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Overexpression of USP8 inhibits inflammation and ferroptosis in chronic obstructive pulmonary disease by regulating the OTUB1/SLC7A11 signaling pathway

Allergologia et immunopathologia, 2024-01, Vol.52 (4), p.60-67

2024

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The Ubiquitin-Specific Protease 18 Promotes Hepatitis C Virus Production by Increasing Viral Infectivity

Mediators of inflammation, 2019, Vol.2019 (2019), p.1-12

2019

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OTUD5 promotes innate antiviral and antitumor immunity through deubiquitinating and stabilizing STING

Cellular & molecular immunology, 2021-08, Vol.18 (8), p.1945-1955

2021

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Deubiquitylation and regulation of the immune response

Nature reviews. Immunology, 2008-07, Vol.8 (7), p.501-511

Sun, Shao-Cong

2008

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Mixed Lineage Leukemia 5 (MLL5) Protein Stability Is Cooperatively Regulated by O-GlcNac Transferase (OGT) and Ubiquitin Specific Protease 7 (USP7)

PloS one, 2015-12, Vol.10 (12), p.e0145023-e0145023

2015

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Deubiquitinase USP1 enhances CCAAT/enhancer-binding protein beta (C/EBPβ) stability and accelerates adipogenesis and lipid accumulation

Cell death & disease, 2023-11, Vol.14 (11), p.776-776, Article 776

2023

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Inhibition of USP1 activates ER stress through Ubi-protein aggregation to induce autophagy and apoptosis in HCC

Cell death & disease, 2022-11, Vol.13 (11), p.951-951, Article 951

2022

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FAM188B enhances cell survival via interaction with USP7

Cell death & disease, 2018-05, Vol.9 (6), p.633-13, Article 633

2018

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USP5 facilitates non-small cell lung cancer progression through stabilization of PD-L1

Cell death & disease, 2021-11, Vol.12 (11), p.1051-1051, Article 1051

2021

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USP1-regulated reciprocal differentiation of Th17 cells and Treg cells by deubiquitinating and stabilizing TAZ

Cellular & molecular immunology, 2023-03, Vol.20 (3), p.252-263

2023

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Chemical derivatives of a small molecule deubiquitinase inhibitor have antiviral activity against several RNA viruses

PloS one, 2014-04, Vol.9 (4), p.e94491

2014

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Deubiquitylase OTUD3 prevents Parkinson’s disease through stabilizing iron regulatory protein 2

Cell death & disease, 2022-04, Vol.13 (4), p.418-418, Article 418

2022

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Ubiquitin-Specific Protease 2 Modulates the Lipopolysaccharide-Elicited Expression of Proinflammatory Cytokines in Macrophage-like HL-60 Cells

Mediators of inflammation, 2017-01, Vol.2017 (2017), p.1-15

2017

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Induction of OTUD1 by RNA viruses potently inhibits innate immune responses by promoting degradation of the MAVS/TRAF3/TRAF6 signalosome

USP27X negatively regulates antiviral signaling by deubiquitinating RIG-I

Ubiquitin specific peptidase 4 stabilizes interferon regulatory factor protein and promotes its function to facilitate interleukin-4 expression in T helper type 2 cells

A putative OTU domain-containing protein 1 deubiquitinating enzyme is differentially expressed in thyroid cancer and identifies less-aggressive tumours

Monoclonal Antibody Specific for Ovarian Tumor Domain-Containing Protein 1

Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60

Induction of OTUD4 by viral infection promotes antiviral responses through deubiquitinating and stabilizing MAVS

Cancer cell-derived exosomal circUSP7 induces CD8 + T cell dysfunction and anti-PD1 resistance by regulating the miR-934/SHP2 axis in NSCLC

USP13 negatively regulates antiviral responses by deubiquitinating STING

USP15: a review of its implication in immune and inflammatory processes and tumor progression

The deubiquitinase OTUD1 enhances iron transport and potentiates host antitumor immunity

Ubiquitin-Specific Protease 43 Impacts Pancreatic Ductal Adenocarcinoma Prognosis by Altering Its Proliferation and Infiltration of Surrounding Immune Cells

Overexpression of USP8 inhibits inflammation and ferroptosis in chronic obstructive pulmonary disease by regulating the OTUB1/SLC7A11 signaling pathway

The Ubiquitin-Specific Protease 18 Promotes Hepatitis C Virus Production by Increasing Viral Infectivity

OTUD5 promotes innate antiviral and antitumor immunity through deubiquitinating and stabilizing STING

Deubiquitylation and regulation of the immune response

Mixed Lineage Leukemia 5 (MLL5) Protein Stability Is Cooperatively Regulated by O-GlcNac Transferase (OGT) and Ubiquitin Specific Protease 7 (USP7)

Deubiquitinase USP1 enhances CCAAT/enhancer-binding protein beta (C/EBPβ) stability and accelerates adipogenesis and lipid accumulation

Inhibition of USP1 activates ER stress through Ubi-protein aggregation to induce autophagy and apoptosis in HCC

FAM188B enhances cell survival via interaction with USP7

USP5 facilitates non-small cell lung cancer progression through stabilization of PD-L1

USP1-regulated reciprocal differentiation of Th17 cells and Treg cells by deubiquitinating and stabilizing TAZ

Chemical derivatives of a small molecule deubiquitinase inhibitor have antiviral activity against several RNA viruses

Deubiquitylase OTUD3 prevents Parkinson’s disease through stabilizing iron regulatory protein 2

Ubiquitin-Specific Protease 2 Modulates the Lipopolysaccharide-Elicited Expression of Proinflammatory Cytokines in Macrophage-like HL-60 Cells

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