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Protein dynamics and conformational disorder in molecular recognition

Journal of molecular recognition, 2010-03, Vol.23 (2), p.105-116

2010

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From Sequence and Forces to Structure, Function, and Evolution of Intrinsically Disordered Proteins

Structure (London), 2013-09, Vol.21 (9), p.1492-1499

2013

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Phospho-dependent phase separation of FMRP and CAPRIN1 recapitulates regulation of translation and deadenylation

Science (American Association for the Advancement of Science), 2019-08, Vol.365 (6455), p.825-829

2019

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Entropy and Information within Intrinsically Disordered Protein Regions

Entropy (Basel, Switzerland), 2019-07, Vol.21 (7), p.662

2019

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Phosphoregulated FMRP phase separation models activity-dependent translation through bidirectional control of mRNA granule formation

Proceedings of the National Academy of Sciences - PNAS, 2019-03, Vol.116 (10), p.4218-4227

2019

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Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch

Nature (London), 2015-03, Vol.519 (7541), p.106-109

2015

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Structural and hydrodynamic properties of an intrinsically disordered region of a germ cell-specific protein on phase separation

Proceedings of the National Academy of Sciences - PNAS, 2017-09, Vol.114 (39), p.E8194-E8203

2017

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Sequence Determinants of Compaction in Intrinsically Disordered Proteins

Biophysical journal, 2010-05, Vol.98 (10), p.2383-2390

2010

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Charge pattern matching as a 'fuzzy' mode of molecular recognition for the functional phase separations of intrinsically disordered proteins

New journal of physics, 2017-11, Vol.19 (11), p.115003

2017

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Conformations of a Metastable SH3 Domain Characterized by smFRET and an Excluded-Volume Polymer Model

Biophysical journal, 2016-04, Vol.110 (7), p.1510-1522

2016

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Role of CBS and Bateman Domains in Phosphorylation-Dependent Regulation of a CLC Anion Channel

Biophysical journal, 2016-11, Vol.111 (9), p.1876-1886

2016

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Dynamic Protein Interaction Networks and New Structural Paradigms in Signaling

Chemical reviews, 2016-06, Vol.116 (11), p.6424-6462

2016

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Mapping the per-residue surface electrostatic potential of CAPRIN1 along its phase-separation trajectory

Proceedings of the National Academy of Sciences - PNAS, 2022-09, Vol.119 (36), p.e2210492119-e2210492119

2022

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Proteome-wide signatures of function in highly diverged intrinsically disordered regions

eLife, 2019-07, Vol.8

2019

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Identifying molecular features that are associated with biological function of intrinsically disordered protein regions

eLife, 2021-02, Vol.10

2021

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Regulatory R region of the CFTR chloride channel is a dynamic integrator of phospho-dependent intra- and intermolecular interactions

Proceedings of the National Academy of Sciences - PNAS, 2013-11, Vol.110 (47), p.E4427-E4436

2013

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Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor

Proceedings of the National Academy of Sciences - PNAS, 2008-11, Vol.105 (46), p.17772-17777

2008

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An Interpretable Machine-Learning Algorithm to Predict Disordered Protein Phase Separation Based on Biophysical Interactions

Biomolecules (Basel, Switzerland), 2022-08, Vol.12 (8), p.1131

2022

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Non-cooperative 4E-BP2 folding with exchange between eIF4E-binding and binding-incompatible states tunes cap-dependent translation inhibition

Nature communications, 2020-06, Vol.11 (1), p.3146-18, Article 3146

2020

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Autoinhibition of the HECT-Type Ubiquitin Ligase Smurf2 through Its C2 Domain

Cell, 2007-08, Vol.130 (4), p.651-662

2007

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Configurational Entropy of Folded Proteins and Its Importance for Intrinsically Disordered Proteins

International journal of molecular sciences, 2021-03, Vol.22 (7), p.3420

2021

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Structural Diversity in Free and Bound States of Intrinsically Disordered Protein Phosphatase 1 Regulators

Structure (London), 2010-09, Vol.18 (9), p.1094-1103

2010

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Sequence-Specific Polyampholyte Phase Separation in Membraneless Organelles

Physical review letters, 2016-10, Vol.117 (17), p.178101-178101, Article 178101

2016

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Comparative roles of charge, π, and hydrophobic interactions in sequence-dependent phase separation of intrinsically disordered proteins

Proceedings of the National Academy of Sciences - PNAS, 2020-11, Vol.117 (46), p.28795-28805

2020

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Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity

Proceedings of the National Academy of Sciences - PNAS, 2010-10, Vol.107 (43), p.18404-18409

2010

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Protein dynamics and conformational disorder in molecular recognition

From Sequence and Forces to Structure, Function, and Evolution of Intrinsically Disordered Proteins

Phospho-dependent phase separation of FMRP and CAPRIN1 recapitulates regulation of translation and deadenylation

Entropy and Information within Intrinsically Disordered Protein Regions

Phosphoregulated FMRP phase separation models activity-dependent translation through bidirectional control of mRNA granule formation

Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch

Structural and hydrodynamic properties of an intrinsically disordered region of a germ cell-specific protein on phase separation

Sequence Determinants of Compaction in Intrinsically Disordered Proteins

Charge pattern matching as a 'fuzzy' mode of molecular recognition for the functional phase separations of intrinsically disordered proteins

Conformations of a Metastable SH3 Domain Characterized by smFRET and an Excluded-Volume Polymer Model

Role of CBS and Bateman Domains in Phosphorylation-Dependent Regulation of a CLC Anion Channel

Dynamic Protein Interaction Networks and New Structural Paradigms in Signaling

Mapping the per-residue surface electrostatic potential of CAPRIN1 along its phase-separation trajectory

Proteome-wide signatures of function in highly diverged intrinsically disordered regions

Identifying molecular features that are associated with biological function of intrinsically disordered protein regions

Regulatory R region of the CFTR chloride channel is a dynamic integrator of phospho-dependent intra- and intermolecular interactions

Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor

An Interpretable Machine-Learning Algorithm to Predict Disordered Protein Phase Separation Based on Biophysical Interactions

Non-cooperative 4E-BP2 folding with exchange between eIF4E-binding and binding-incompatible states tunes cap-dependent translation inhibition

Autoinhibition of the HECT-Type Ubiquitin Ligase Smurf2 through Its C2 Domain

Configurational Entropy of Folded Proteins and Its Importance for Intrinsically Disordered Proteins

Structural Diversity in Free and Bound States of Intrinsically Disordered Protein Phosphatase 1 Regulators

Sequence-Specific Polyampholyte Phase Separation in Membraneless Organelles

Comparative roles of charge, π, and hydrophobic interactions in sequence-dependent phase separation of intrinsically disordered proteins

Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity

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