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Cold Spot SCANNER: Colab Notebook for predicting cold spots in protein-protein interfaces

BMC bioinformatics, 2024-04, Vol.25 (1), p.172-172, Article 172

2024

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Generating quantitative binding landscapes through fractional binding selections combined with deep sequencing and data normalization

Nature communications, 2020-01, Vol.11 (1), p.297-297, Article 297

2020

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Computational design and experimental optimization of protein binders with prospects for biomedical applications

Protein engineering, design and selection, 2021-08, Vol.34

2021

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Targeting Ras with protein engineering

Oncotarget, 2023-07, Vol.14 (1), p.672-687

2023

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Cold Spots in Protein Binding

Trends in biochemical sciences (Amsterdam. Regular ed.), 2016-09, Vol.41 (9), p.739-745

2016

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Protein Engineering by Combined Computational and In Vitro Evolution Approaches

Trends in biochemical sciences (Amsterdam. Regular ed.), 2016-05, Vol.41 (5), p.421-433

2016

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Engineered variants of the Ras effector protein RASSF5 (NORE1A) promote anticancer activities in lung adenocarcinoma

The Journal of biological chemistry, 2021-12, Vol.297 (6), p.101353, Article 101353

2021

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Designed Loop Extension Followed by Combinatorial Screening Confers High Specificity to a Broad Matrix MetalloproteinaseInhibitor

Journal of molecular biology, 2023-07, Vol.435 (13), p.168095, Article 168095

2023

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Cold spots are universal in protein–protein interactions

Protein science, 2022-10, Vol.31 (10), p.e4435-n/a

2022

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Converting a broad matrix metalloproteinase family inhibitor into a specific inhibitor of MMP‐9 and MMP‐14

FEBS letters, 2018-04, Vol.592 (7), p.1122-1134

2018

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Editorial overview: Engineering and design: New trends in designer proteins

Current opinion in structural biology, 2017-08, Vol.45, p.iv-vi

2017

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Identifying Residues that Determine SCF Molecular-Level Interactions through a Combination of Experimental and In silico Analyses

Journal of molecular biology, 2017-01, Vol.429 (1), p.97-114

2017

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Alteration of the C-Terminal Ligand Specificity of the Erbin PDZ Domain by Allosteric Mutational Effects

Journal of molecular biology, 2014-10, Vol.426 (21), p.3500-3508

2014

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Heme Redox Potential Control in de Novo Designed Four-α-Helix Bundle Proteins

Biochemistry (Easton), 2000-12, Vol.39 (48), p.14813-14821

2000

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Computational design of an integrin I domain stabilized in the open high affinity conformation

Nature structural & molecular biology, 2000-08, Vol.7 (8), p.674-678

2000

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Designed Loop Extension Followed by Combinatorial Screening Confers High Specificity to a Broad Matrix Metalloproteinase Inhibitor

Journal of molecular biology, 2023-07, Vol.435 (13), p.168095-168095, Article 168095

2023

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Functionalized de Novo Designed Proteins: Mechanism of Proton Coupling to Oxidation/Reduction in Heme Protein Maquettes

Biochemistry (Easton), 1998-11, Vol.37 (47), p.16815-16827

1998

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Cold Spot SCANNER: Colab Notebook for predicting cold spots in protein-protein interfaces

Generating quantitative binding landscapes through fractional binding selections combined with deep sequencing and data normalization

Computational design and experimental optimization of protein binders with prospects for biomedical applications

Targeting Ras with protein engineering

Cold Spots in Protein Binding

Protein Engineering by Combined Computational and In Vitro Evolution Approaches

Engineered variants of the Ras effector protein RASSF5 (NORE1A) promote anticancer activities in lung adenocarcinoma

Designed Loop Extension Followed by Combinatorial Screening Confers High Specificity to a Broad Matrix MetalloproteinaseInhibitor

Cold spots are universal in protein–protein interactions

Converting a broad matrix metalloproteinase family inhibitor into a specific inhibitor of MMP‐9 and MMP‐14

Editorial overview: Engineering and design: New trends in designer proteins

Identifying Residues that Determine SCF Molecular-Level Interactions through a Combination of Experimental and In silico Analyses

Alteration of the C-Terminal Ligand Specificity of the Erbin PDZ Domain by Allosteric Mutational Effects

Heme Redox Potential Control in de Novo Designed Four-α-Helix Bundle Proteins

Computational design of an integrin I domain stabilized in the open high affinity conformation

Designed Loop Extension Followed by Combinatorial Screening Confers High Specificity to a Broad Matrix Metalloproteinase Inhibitor

Functionalized de Novo Designed Proteins: Mechanism of Proton Coupling to Oxidation/Reduction in Heme Protein Maquettes

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