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L-Type amino acid transporter 1 (LAT1)-utilizing prodrugs are carrier-selective despite having low affinity for organic anion transporting polypeptides (OATPs)

International journal of pharmaceutics, 2019-11, Vol.571, p.118714, Article 118714

2019

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Prodrugs - an efficient way to breach delivery and targeting barriers

Current topics in medicinal chemistry, 2011-09, Vol.11 (18), p.2265

2011

Volltextzugriff (PDF)

Amino acids as promoieties in prodrug design and development

Advanced drug delivery reviews, 2013-10, Vol.65 (10), p.1370-1385

2013

Volltextzugriff (PDF)

L-Type Amino Acid Transporter 1 (LAT1/Lat1)-Utilizing Prodrugs Can Improve the Delivery of Drugs into Neurons, Astrocytes and Microglia

Scientific reports, 2019-09, Vol.9 (1), p.12860-12, Article 12860

2019

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Sodium-Dependent Neutral Amino Acid Transporter 2 Can Serve as a Tertiary Carrier for l‑Type Amino Acid Transporter 1‑Utilizing Prodrugs

Molecular pharmaceutics, 2023-02, Vol.20 (2), p.1331-1346

2023

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Structural Features Affecting the Interactions and Transportability of LAT1-Targeted Phenylalanine Drug Conjugates

Molecular pharmaceutics, 2023-01, Vol.20 (1), p.206-218

2023

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l-Type amino acid transporter 1 (lat1)-mediated targeted delivery of perforin inhibitors

International journal of pharmaceutics, 2016-02, Vol.498 (1-2), p.205-216

2016

Volltextzugriff (PDF)

Sustained Release of Metformin via Red Blood Cell Accumulated Sulfenamide Prodrug

Journal of pharmaceutical sciences, 2014-07, Vol.103 (7), p.2207-2210

2014

Volltextzugriff (PDF)

Secondary carbamate linker can facilitate the sustained release of dopamine from brain-targeted prodrug

Bioorganic & medicinal chemistry letters, 2018-09, Vol.28 (17), p.2856-2860

2018

Volltextzugriff (PDF)

Glutathione-S-transferase selective release of metformin from its sulfonamide prodrug

Bioorganic & medicinal chemistry letters, 2014-11, Vol.24 (21), p.5034-5036

2014

Volltextzugriff (PDF)

Altering distribution profile of palbociclib by its prodrugs

European journal of pharmaceutical sciences, 2024-01, Vol.192, p.106637-106637, Article 106637

2024

Volltextzugriff (PDF)

Cytochrome P450-activated prodrugs: targeted drug delivery

Current medicinal chemistry, 2008-10, Vol.15 (23), p.2346

2008

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Metformin and Its Sulfenamide Prodrugs Inhibit Human Cholinesterase Activity

Oxidative medicine and cellular longevity, 2017-01, Vol.2017 (1), p.7303096-7303096

2017

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The First Bioreversible Prodrug of Metformin with Improved Lipophilicity and Enhanced Intestinal Absorption

Journal of medicinal chemistry, 2009-07, Vol.52 (14), p.4142-4148

2009

Volltextzugriff (PDF)

Design, Synthesis, and Evaluation of Novel Cyclic Phosphates of 5‑Aminosalicylic Acid as Cytochrome P450-Activated Prodrugs

Molecular pharmaceutics, 2013-02, Vol.10 (2), p.532-537

2013

Volltextzugriff (PDF)

Design, Synthesis and Brain Uptake of LAT1-Targeted Amino Acid Prodrugs of Dopamine

Pharmaceutical research, 2013-10, Vol.30 (10), p.2523-2537

2013

Volltextzugriff (PDF)

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L-Type amino acid transporter 1 (LAT1)-utilizing prodrugs are carrier-selective despite having low affinity for organic anion transporting polypeptides (OATPs)

Prodrugs - an efficient way to breach delivery and targeting barriers

Amino acids as promoieties in prodrug design and development

L-Type Amino Acid Transporter 1 (LAT1/Lat1)-Utilizing Prodrugs Can Improve the Delivery of Drugs into Neurons, Astrocytes and Microglia

Sodium-Dependent Neutral Amino Acid Transporter 2 Can Serve as a Tertiary Carrier for l‑Type Amino Acid Transporter 1‑Utilizing Prodrugs

Structural Features Affecting the Interactions and Transportability of LAT1-Targeted Phenylalanine Drug Conjugates

l-Type amino acid transporter 1 (lat1)-mediated targeted delivery of perforin inhibitors

Sustained Release of Metformin via Red Blood Cell Accumulated Sulfenamide Prodrug

Secondary carbamate linker can facilitate the sustained release of dopamine from brain-targeted prodrug

Glutathione-S-transferase selective release of metformin from its sulfonamide prodrug

Altering distribution profile of palbociclib by its prodrugs

Cytochrome P450-activated prodrugs: targeted drug delivery

Metformin and Its Sulfenamide Prodrugs Inhibit Human Cholinesterase Activity

The First Bioreversible Prodrug of Metformin with Improved Lipophilicity and Enhanced Intestinal Absorption

Design, Synthesis, and Evaluation of Novel Cyclic Phosphates of 5‑Aminosalicylic Acid as Cytochrome P450-Activated Prodrugs

Design, Synthesis and Brain Uptake of LAT1-Targeted Amino Acid Prodrugs of Dopamine

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