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Antibody to Poly-N-acetyl glucosamine provides protection against intracellular pathogens: Mechanism of action and validation in horse foals challenged with Rhodococcus equi

PLoS pathogens, 2018-07, Vol.14 (7), p.e1007160-e1007160

2018

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Rhodococcus equi foal pneumonia: Update on epidemiology, immunity, treatment and prevention

Equine veterinary journal, 2022-05, Vol.54 (3), p.481-494

2022

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The opportunistic intracellular bacterial pathogen Rhodococcus equi elicits type I interferon by engaging cytosolic DNA sensing in macrophages

PLoS pathogens, 2021-09, Vol.17 (9), p.e1009888-e1009888

2021

Volltextzugriff (PDF)

Rhodococcus equi Foal Pneumonia

The Veterinary clinics of North America. Equine practice, 2014-12, Vol.30 (3), p.609-622

Cohen, Noah D.

2014

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Antibody activities in hyperimmune plasma against the Rhodococcus equi virulence -associated protein A or poly-N-acetyl glucosamine are associated with protection of foals against rhodococcal pneumonia

PloS one, 2021-08, Vol.16 (8), p.e0250133

2021

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Host-directed therapy in foals can enhance functional innate immunity and reduce severity of Rhodococcus equi pneumonia

Scientific reports, 2021-01, Vol.11 (1), p.2483-2483, Article 2483

2021

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Macrolide- and rifampin-resistant Rhodococcus equi on a horse breeding farm, Kentucky, USA

Emerging infectious diseases, 2013-02, Vol.19 (2), p.282-285

2013

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Oral Administration of Electron-Beam Inactivated Rhodococcus equi Failed to Protect Foals against Intrabronchial Infection with Live, Virulent R. equi

PloS one, 2016-02, Vol.11 (2), p.e0148111-e0148111

2016

Volltextzugriff (PDF)

Prevalence and risk factors associated with emergence of Rhodococcus equi resistance to macrolides and rifampicin in horse-breeding farms in Kentucky, USA

Veterinary microbiology, 2019-08, Vol.235, p.243-247

2019

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Emergence of Resistance to Macrolides and Rifampin in Clinical Isolates of Rhodococcus equi from Foals in Central Kentucky, 1995 to 2017

Antimicrobial agents and chemotherapy, 2019-01, Vol.63 (1)

2019

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Opsonization but not pretreatment of equine macrophages with hyperimmune plasma nonspecifically enhances phagocytosis and intracellular killing of Rhodococcus equi

Journal of veterinary internal medicine, 2021-01, Vol.35 (1), p.590-596

2021

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Composition and Diversity of the Fecal Microbiome and Inferred Fecal Metagenome Does Not Predict Subsequent Pneumonia Caused by Rhodococcus equi in Foals

PloS one, 2015-08, Vol.10 (8), p.e0136586-e0136586

2015

Volltextzugriff (PDF)

Impact of surface receptors TLR2, CR3, and FcγRIII on Rhodococcus equi phagocytosis and intracellular survival in macrophages

Infection and immunity, 2024-01, Vol.92 (1), p.e0038323-e0038323

2024

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Association of pneumonia with concentrations of virulent Rhodococcus equi in fecal swabs of foals before and after intrabronchial infection with virulent R. equi

Journal of veterinary internal medicine, 2022-05, Vol.36 (3), p.1139-1145

2022

Volltextzugriff (PDF)

Fecal concentration of Rhodococcus equi determined by quantitative polymerase chain reaction of rectal swab samples to differentiate foals with pneumonia from healthy foals

Journal of veterinary internal medicine, 2022-05, Vol.36 (3), p.1146-1151

2022

Volltextzugriff (PDF)

In vitro evaluation of complement deposition and opsonophagocytic killing of Rhodococcus equi mediated by poly‐N‐acetyl glucosamine hyperimmune plasma compared to commercial plasma products

Journal of veterinary internal medicine, 2019-05, Vol.33 (3), p.1493-1499

2019

Volltextzugriff (PDF)

Randomized, controlled trial comparing Rhodococcus equi and poly‐N‐acetyl glucosamine hyperimmune plasma to prevent R equi pneumonia in foals

Journal of veterinary internal medicine, 2021-11, Vol.35 (6), p.2912-2919

2021

Volltextzugriff (PDF)

Immunogenicity of an electron beam inactivated Rhodococcus equi vaccine in neonatal foals

PloS one, 2014-08, Vol.9 (8), p.e105367-e105367

2014

Volltextzugriff (PDF)

Intramuscular administration of a synthetic CpG-oligodeoxynucleotide modulates functional responses of neutrophils of neonatal foals

PloS one, 2014-10, Vol.9 (10), p.e109865

2014

Volltextzugriff (PDF)

Update on Bacterial Pneumonia in the Foal and Weanling

The Veterinary clinics of North America. Equine practice, 2015-04, Vol.31 (1), p.121-135

2015

Volltextzugriff (PDF)

Effects of administration of live or inactivated virulent Rhodococccus equi and age on the fecal microbiome of neonatal foals

PloS one, 2013-06, Vol.8 (6), p.e66640-e66640

2013

Volltextzugriff (PDF)

Transfusion of hyperimmune plasma for protecting foals against Rhodococcus equi pneumonia

Equine veterinary journal, 2023-05, Vol.55 (3), p.376-388

2023

Volltextzugriff (PDF)

Antimicrobial Residue Accumulation Contributes to Higher Levels of Rhodococcus equi Carrying Resistance Genes in the Environment of Horse-Breeding Farms

Veterinary sciences, 2024-02, Vol.11 (2), p.92

2024

Volltextzugriff (PDF)

Serum activities of complement 1q and antibodies to the virulence-associated protein A are lower in foals that develop rhodococcal pneumonia

American journal of veterinary research, 2024-01, p.1-10

2024

Volltextzugriff (PDF)

Identification of genomic loci associated with Rhodococcus equi susceptibility in foals

PloS one, 2014-06, Vol.9 (6), p.e98710-e98710

2014

Volltextzugriff (PDF)

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Antibody to Poly-N-acetyl glucosamine provides protection against intracellular pathogens: Mechanism of action and validation in horse foals challenged with Rhodococcus equi

Rhodococcus equi foal pneumonia: Update on epidemiology, immunity, treatment and prevention

The opportunistic intracellular bacterial pathogen Rhodococcus equi elicits type I interferon by engaging cytosolic DNA sensing in macrophages

Rhodococcus equi Foal Pneumonia

Antibody activities in hyperimmune plasma against the Rhodococcus equi virulence -associated protein A or poly-N-acetyl glucosamine are associated with protection of foals against rhodococcal pneumonia

Host-directed therapy in foals can enhance functional innate immunity and reduce severity of Rhodococcus equi pneumonia

Macrolide- and rifampin-resistant Rhodococcus equi on a horse breeding farm, Kentucky, USA

Oral Administration of Electron-Beam Inactivated Rhodococcus equi Failed to Protect Foals against Intrabronchial Infection with Live, Virulent R. equi

Prevalence and risk factors associated with emergence of Rhodococcus equi resistance to macrolides and rifampicin in horse-breeding farms in Kentucky, USA

Emergence of Resistance to Macrolides and Rifampin in Clinical Isolates of Rhodococcus equi from Foals in Central Kentucky, 1995 to 2017

Opsonization but not pretreatment of equine macrophages with hyperimmune plasma nonspecifically enhances phagocytosis and intracellular killing of Rhodococcus equi

Composition and Diversity of the Fecal Microbiome and Inferred Fecal Metagenome Does Not Predict Subsequent Pneumonia Caused by Rhodococcus equi in Foals

Impact of surface receptors TLR2, CR3, and FcγRIII on Rhodococcus equi phagocytosis and intracellular survival in macrophages

Association of pneumonia with concentrations of virulent Rhodococcus equi in fecal swabs of foals before and after intrabronchial infection with virulent R. equi

Fecal concentration of Rhodococcus equi determined by quantitative polymerase chain reaction of rectal swab samples to differentiate foals with pneumonia from healthy foals

In vitro evaluation of complement deposition and opsonophagocytic killing of Rhodococcus equi mediated by poly‐N‐acetyl glucosamine hyperimmune plasma compared to commercial plasma products

Randomized, controlled trial comparing Rhodococcus equi and poly‐N‐acetyl glucosamine hyperimmune plasma to prevent R equi pneumonia in foals

Immunogenicity of an electron beam inactivated Rhodococcus equi vaccine in neonatal foals

Intramuscular administration of a synthetic CpG-oligodeoxynucleotide modulates functional responses of neutrophils of neonatal foals

Update on Bacterial Pneumonia in the Foal and Weanling

Effects of administration of live or inactivated virulent Rhodococccus equi and age on the fecal microbiome of neonatal foals

Transfusion of hyperimmune plasma for protecting foals against Rhodococcus equi pneumonia

Antimicrobial Residue Accumulation Contributes to Higher Levels of Rhodococcus equi Carrying Resistance Genes in the Environment of Horse-Breeding Farms

Serum activities of complement 1q and antibodies to the virulence-associated protein A are lower in foals that develop rhodococcal pneumonia

Identification of genomic loci associated with Rhodococcus equi susceptibility in foals

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