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Mycobacterium tuberculosis Dethiobiotin Synthetase Facilitates Nucleoside Triphosphate Promiscuity through Alternate Binding Modes

ACS catalysis, 2018-11, Vol.8 (11), p.10774-10783

2018

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An antimony-phosphomolybdate microassay of ATPase activity through the detection of inorganic phosphate

Analytical biochemistry, 2021-06, Vol.623, p.114170-114170, Article 114170

2021

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Structural insights into the antifungal drug target guanosine monophosphate synthase from Aspergillus fumigatus

Acta crystallographica. Section D, Biological crystallography., 2022-02, Vol.78 (2), p.248-259

2022

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An In Crystallo Reaction with an Engineered Cytochrome P450 Peroxygenase

Chemistry : a European journal, 2024-02, Vol.30 (8), p.e202303335-n/a

2024

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Investigating the Active Oxidants Involved in Cytochrome P450 Catalyzed Sulfoxidation Reactions

Chemistry : a European journal, 2022-12, Vol.28 (72), p.e202202428-n/a

2022

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Structure-guided design and synthesis of ATP-competitive N-acyl-substituted sulfamide d-alanine-d-alanine ligase inhibitors

Bioorganic & medicinal chemistry, 2023-12, Vol.96, p.117509-117509, Article 117509

2023

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A comparison of steroid and lipid binding cytochrome P450s from Mycobacterium marinum and Mycobacterium tuberculosis

Journal of inorganic biochemistry, 2020-08, Vol.209, p.111116-111116, Article 111116

2020

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The Oxidation of Oxygen and Sulfur-Containing Heterocycles by Cytochrome P450 Enzymes

Chemistry : a European journal, 2023-09, Vol.29 (50), p.e202301371-e202301371

2023

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Identification and characterisation of MdUGT78T2 as a galactosyltransferase with dual activity on flavonol and anthocyanidin substrates in red-skinned apple fruit (Malus domestica L.)

Food chemistry, 2023-10, Vol.424, p.136388-136388, Article 136388

2023

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An Altered Heme Environment in an Engineered Cytochrome P450 Enzyme Enables the Switch from Monooxygenase to Peroxygenase Activity

ACS catalysis, 2022-02, Vol.12 (3), p.1614-1625

2022

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A turn-on fluorescent PCNA sensor

Bioorganic & medicinal chemistry letters, 2021-06, Vol.41, p.128031-128031, Article 128031

2021

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Structural insights into the role of the acid-alcohol pair of residues required for dioxygen activation in cytochrome P450 enzymes

Journal of biological inorganic chemistry, 2020-06, Vol.25 (4), p.583-596

2020

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Investigation of the requirements for efficient and selective cytochrome P450 monooxygenase catalysis across different reactions

Journal of inorganic biochemistry, 2020-02, Vol.203, p.110913-110913, Article 110913

2020

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Engineering C–C Bond Cleavage Activity into a P450 Monooxygenase Enzyme

Journal of the American Chemical Society, 2023-04, Vol.145 (16), p.9207-9222

2023

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Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering

Chemistry : a European journal, 2022-12, Vol.28 (67), p.e202201895-n/a

2022

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Understanding the Mechanistic Requirements for Efficient and Stereoselective Alkene Epoxidation by a Cytochrome P450 Enzyme

ACS catalysis, 2021-02, Vol.11 (4), p.1995-2010

2021

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To Be, or Not to Be, an Inhibitor: A Comparison of Azole Interactions with and Oxidation by a Cytochrome P450 Enzyme

Inorganic chemistry, 2022-01, Vol.61 (1), p.236-245

2022

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Cytochrome P450 CYP199A4 from Rhodopseudomonas palustris Catalyzes Heteroatom Dealkylations, Sulfoxidation, and Amide and Cyclic Hemiacetal Formation

ACS catalysis, 2018-07, Vol.8 (7), p.5915-5927

2018

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The Stereoselective Oxidation of para‐Substituted Benzenes by a Cytochrome P450 Biocatalyst

Chemistry : a European journal, 2021-10, Vol.27 (59), p.14765-14777

2021

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Characterisation of the heme aqua-ligand coordination environment in an engineered peroxygenase cytochrome P450 variant

Journal of inorganic biochemistry, 2023-12, Vol.249, p.112391-112391, Article 112391

2023

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Cytochrome P450-catalyzed oxidation of halogen-containing substrates

Journal of inorganic biochemistry, 2023-07, Vol.244, p.112234-112234, Article 112234

2023

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Exploring the Factors which Result in Cytochrome P450 Catalyzed Desaturation Versus Hydroxylation

Chemistry, an Asian journal, 2022-12, Vol.17 (24), p.e202200986-n/a

2022

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Combining random microseed matrix screening and the magic triangle for the efficient structure solution of a potential lysin from bacteriophage P68

Acta crystallographica. Section D, Biological crystallography., 2019-07, Vol.75 (7), p.670-681

2019

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warpDOCK: Large-Scale Virtual Drug Discovery Using Cloud Infrastructure

ACS omega, 2023-08, Vol.8 (32), p.29143-29149

2023

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Structure of Aspergillus fumigatus Cytosolic Thiolase: Trapped Tetrahedral Reaction Intermediates and Activation by Monovalent Cations

ACS catalysis, 2018-03, Vol.8 (3), p.1973-1989

2018

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Mycobacterium tuberculosis Dethiobiotin Synthetase Facilitates Nucleoside Triphosphate Promiscuity through Alternate Binding Modes

An antimony-phosphomolybdate microassay of ATPase activity through the detection of inorganic phosphate

Structural insights into the antifungal drug target guanosine monophosphate synthase from Aspergillus fumigatus

An In Crystallo Reaction with an Engineered Cytochrome P450 Peroxygenase

Investigating the Active Oxidants Involved in Cytochrome P450 Catalyzed Sulfoxidation Reactions

Structure-guided design and synthesis of ATP-competitive N-acyl-substituted sulfamide d-alanine-d-alanine ligase inhibitors

A comparison of steroid and lipid binding cytochrome P450s from Mycobacterium marinum and Mycobacterium tuberculosis

The Oxidation of Oxygen and Sulfur-Containing Heterocycles by Cytochrome P450 Enzymes

Identification and characterisation of MdUGT78T2 as a galactosyltransferase with dual activity on flavonol and anthocyanidin substrates in red-skinned apple fruit (Malus domestica L.)

An Altered Heme Environment in an Engineered Cytochrome P450 Enzyme Enables the Switch from Monooxygenase to Peroxygenase Activity

A turn-on fluorescent PCNA sensor

Structural insights into the role of the acid-alcohol pair of residues required for dioxygen activation in cytochrome P450 enzymes

Investigation of the requirements for efficient and selective cytochrome P450 monooxygenase catalysis across different reactions

Engineering C–C Bond Cleavage Activity into a P450 Monooxygenase Enzyme

Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering

Understanding the Mechanistic Requirements for Efficient and Stereoselective Alkene Epoxidation by a Cytochrome P450 Enzyme

To Be, or Not to Be, an Inhibitor: A Comparison of Azole Interactions with and Oxidation by a Cytochrome P450 Enzyme

Cytochrome P450 CYP199A4 from Rhodopseudomonas palustris Catalyzes Heteroatom Dealkylations, Sulfoxidation, and Amide and Cyclic Hemiacetal Formation

The Stereoselective Oxidation of para‐Substituted Benzenes by a Cytochrome P450 Biocatalyst

Characterisation of the heme aqua-ligand coordination environment in an engineered peroxygenase cytochrome P450 variant

Cytochrome P450-catalyzed oxidation of halogen-containing substrates

Exploring the Factors which Result in Cytochrome P450 Catalyzed Desaturation Versus Hydroxylation

Combining random microseed matrix screening and the magic triangle for the efficient structure solution of a potential lysin from bacteriophage P68

warpDOCK: Large-Scale Virtual Drug Discovery Using Cloud Infrastructure

Structure of Aspergillus fumigatus Cytosolic Thiolase: Trapped Tetrahedral Reaction Intermediates and Activation by Monovalent Cations

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