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Phosphorylation of Synaptic GTPase-activating Protein (synGAP) by Ca2+/Calmodulin-dependent Protein Kinase II (CaMKII) and Cyclin-dependent Kinase 5 (CDK5) Alters the Ratio of Its GAP Activity toward Ras and Rap GTPases

The Journal of biological chemistry, 2015-02, Vol.290 (8), p.4908-4927

2015

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Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (28), p.11381-11386

2011

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Fructose-1,6-bisphosphatase Inhibits ERK Activation and Bypasses Gemcitabine Resistance in Pancreatic Cancer by Blocking IQGAP1-MAPK Interaction

Cancer research (Chicago, Ill.), 2017-08, Vol.77 (16), p.4328-4341

2017

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IQGAP1 and its binding proteins control diverse biological functions

Cellular signalling, 2012-04, Vol.24 (4), p.826-834

2012

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Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis

Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (6), p.2485-2490

2010

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IQGAP1 in cellular signaling: bridging the GAP

Trends in cell biology, 2006-05, Vol.16 (5), p.242-249

2006

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The Primate-Specific Gene TMEM14B Marks Outer Radial Glia Cells and Promotes Cortical Expansion and Folding

Cell stem cell, 2017-11, Vol.21 (5), p.635-649.e8

2017

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Agonist-stimulated phosphatidylinositol-3,4,5-trisphosphate generation by scaffolded phosphoinositide kinases

Nature cell biology, 2016-12, Vol.18 (12), p.1324-1335

2016

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Ligand-dependent spatiotemporal signaling profiles of the μ-opioid receptor are controlled by distinct protein-interaction networks

The Journal of biological chemistry, 2019-11, Vol.294 (44), p.16198-16213

2019

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MAP4K3/GLK Promotes Lung Cancer Metastasis by Phosphorylating and Activating IQGAP1

Cancer research (Chicago, Ill.), 2019-10, Vol.79 (19), p.4978-4993

2019

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Cell cycle-dependent phosphorylation of IQGAP is involved in assembly and stability of the contractile ring in fission yeast

Biochemical and biophysical research communications, 2021-01, Vol.534, p.1026-1032

2021

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SUMOylation of IQGAP1 promotes the development of colorectal cancer

Cancer letters, 2017-12, Vol.411, p.90-99

2017

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Mnk1/2 kinases regulate memory and autism-related behaviours via Syngap1

Brain (London, England : 1878), 2023-05, Vol.146 (5), p.2175-2190

2023

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Simvastatin preparations promote PDGF‐BB secretion to repair LPS‐induced endothelial injury through the PDGFRβ/PI3K/Akt/IQGAP1 signalling pathway

Journal of cellular and molecular medicine, 2019-12, Vol.23 (12), p.8314-8327

2019

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DAB2IP coordinates both PI3K-Akt and ASK1 pathways for cell survival and apoptosis

Proceedings of the National Academy of Sciences - PNAS, 2009-11, Vol.106 (47), p.19878-19883

2009

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Tyrosine phosphorylation of the scaffold protein IQGAP1 in the MET pathway alters function

The Journal of biological chemistry, 2020-12, Vol.295 (52), p.18105-18121

2020

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Efficient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase

The Journal of cell biology, 2008-09, Vol.182 (6), p.1141-1151

2008

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The molecular functions of Shp2 in the Ras/Mitogen-activated protein kinase (ERK1/2) pathway

Cellular signalling, 2008-03, Vol.20 (3), p.453-459

2008

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The RasGAP-Associated Endoribonuclease G3BP Assembles Stress Granules

The Journal of cell biology, 2003-03, Vol.160 (6), p.823-831

2003

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RSPO–LGR4 functions via IQGAP1 to potentiate Wnt signaling

Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (13), p.E1221-E1229

2014

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IQGAP1 regulates cell proliferation through a novel CDC42-mTOR pathway

Journal of cell science, 2009-06, Vol.122 (12), p.2024-2033

2009

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DAB2IP loss confers the resistance of prostate cancer to androgen deprivation therapy through activating STAT3 and inhibiting apoptosis

Cell death & disease, 2015-10, Vol.6 (10), p.e1955-e1955

2015

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STAT3 supports experimental K-RasG12D–induced murine myeloproliferative neoplasms dependent on serine phosphorylation

Blood, 2014-10, Vol.124 (14), p.2252-2261

2014

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IQGAP1 is an oncogenic target in canine melanoma

PloS one, 2017-04, Vol.12 (4), p.e0176370-e0176370

2017

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Phosphorylation of Synaptic GTPase-activating Protein (synGAP) by Ca2+/Calmodulin-dependent Protein Kinase II (CaMKII) and Cyclin-dependent Kinase 5 (CDK5) Alters the Ratio of Its GAP Activity toward Ras and Rap GTPases

Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex

Fructose-1,6-bisphosphatase Inhibits ERK Activation and Bypasses Gemcitabine Resistance in Pancreatic Cancer by Blocking IQGAP1-MAPK Interaction

IQGAP1 and its binding proteins control diverse biological functions

Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis

Mutations in SYNGAP1 Cause Intellectual Disability, Autism, and a Specific Form of Epilepsy by Inducing Haploinsufficiency

IQGAP1 in cellular signaling: bridging the GAP

The Primate-Specific Gene TMEM14B Marks Outer Radial Glia Cells and Promotes Cortical Expansion and Folding

Agonist-stimulated phosphatidylinositol-3,4,5-trisphosphate generation by scaffolded phosphoinositide kinases

Ligand-dependent spatiotemporal signaling profiles of the μ-opioid receptor are controlled by distinct protein-interaction networks

MAP4K3/GLK Promotes Lung Cancer Metastasis by Phosphorylating and Activating IQGAP1

Cell cycle-dependent phosphorylation of IQGAP is involved in assembly and stability of the contractile ring in fission yeast

SUMOylation of IQGAP1 promotes the development of colorectal cancer

Mnk1/2 kinases regulate memory and autism-related behaviours via Syngap1

Simvastatin preparations promote PDGF‐BB secretion to repair LPS‐induced endothelial injury through the PDGFRβ/PI3K/Akt/IQGAP1 signalling pathway

DAB2IP coordinates both PI3K-Akt and ASK1 pathways for cell survival and apoptosis

Tyrosine phosphorylation of the scaffold protein IQGAP1 in the MET pathway alters function

Efficient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase

The molecular functions of Shp2 in the Ras/Mitogen-activated protein kinase (ERK1/2) pathway

The RasGAP-Associated Endoribonuclease G3BP Assembles Stress Granules

RSPO–LGR4 functions via IQGAP1 to potentiate Wnt signaling

IQGAP1 regulates cell proliferation through a novel CDC42-mTOR pathway

DAB2IP loss confers the resistance of prostate cancer to androgen deprivation therapy through activating STAT3 and inhibiting apoptosis

STAT3 supports experimental K-RasG12D–induced murine myeloproliferative neoplasms dependent on serine phosphorylation

IQGAP1 is an oncogenic target in canine melanoma

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