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Mechanisms and functions of p38 MAPK signalling

Biochemical journal, 2010-08, Vol.429 (3), p.403-417

2010

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Diversity and versatility of p38 kinase signalling in health and disease

Nature reviews. Molecular cell biology, 2021-05, Vol.22 (5), p.346-366

2021

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Structural basis of a redox-dependent conformational switch that regulates the stress kinase p38α

Nature communications, 2023-12, Vol.14 (1), p.7920-7920, Article 7920

2023

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P38α/JNK signaling restrains erythropoiesis by suppressing Ezh2-mediated epigenetic silencing of Bim

Nature communications, 2018-08, Vol.9 (1), p.3518-15, Article 3518

2018

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Characterization of p38α autophosphorylation inhibitors that target the non-canonical activation pathway

Nature communications, 2023-06, Vol.14 (1), p.3318-3318, Article 3318

2023

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Changes in the free-energy landscape of p38α MAP kinase through its canonical activation and binding events as studied by enhanced molecular dynamics simulations

eLife, 2017-04, Vol.6

2017

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Myeloid p38α signaling promotes intestinal IGF‐1 production and inflammation‐associated tumorigenesis

EMBO molecular medicine, 2018-07, Vol.10 (7), p.n/a

2018

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Multi-phosphorylation of the Intrinsically Disordered Unique Domain of c-Src Studied by In-Cell and Real-Time NMR Spectroscopy

Chembiochem : a European journal of chemical biology, 2013-09, Vol.14 (14), p.1820-1827

2013

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p38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and aging

PloS one, 2017-02, Vol.12 (2), p.e0171738-e0171738

2017

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Lipid binding by the Unique and SH3 domains of c-Src suggests a new regulatory mechanism

Scientific reports, 2013-02, Vol.3 (1), p.1295-1295, Article 1295

2013

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Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity

Nature genetics, 2002-06, Vol.31 (2), p.210-215

2002

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p38 Mitogen-activated protein kinase- and HuR-dependent stabilization of p21(Cip1) mRNA mediates the G(1)/S checkpoint

Molecular and cellular biology, 2009-08, Vol.29 (16), p.4341-4351

2009

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SnapShot: p38 MAPK Substrates

Cell, 2013-02, Vol.152 (4), p.924-924.e1

2013

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Characterization of p38α Signaling Networks in Cancer Cells Using Quantitative Proteomics and Phosphoproteomics

Molecular & cellular proteomics, 2023-04, Vol.22 (4), p.100527-100527, Article 100527

2023

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Autophagy-induced senescence is regulated by p38α signaling

Cell death & disease, 2019-05, Vol.10 (6), p.376-376, Article 376

2019

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p38 MAPK Enhances STAT1-Dependent Transcription Independently of Ser-727 Phosphorylation

Proceedings of the National Academy of Sciences - PNAS, 2002-10, Vol.99 (20), p.12859-12864

2002

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The Functional Interaction of 14-3-3 Proteins with the ERK1/2 Scaffold KSR1 Occurs in an Isoform-specific Manner

The Journal of biological chemistry, 2008-06, Vol.283 (25), p.17450-17462

2008

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Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions

Biochemical journal, 2003-05, Vol.372 (Pt 1), p.1-13

2003

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p38 MAP kinases: beyond the stress response

Trends in biochemical sciences (Amsterdam. Regular ed.), 2000-06, Vol.25 (6), p.257-260

2000

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CDC25B Phosphorylation by p38 and MK-2

Cell cycle (Georgetown, Tex.), 2006-08, Vol.5 (15), p.1649-1653

2006

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Stress signaling boosts interferon-induced gene transcription in macrophages

Science signaling, 2022-12, Vol.15 (764), p.eabq5389

2022

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Phosphorylation of MRF4 transactivation domain by p38 mediates repression of specific myogenic genes

The EMBO journal, 2004-01, Vol.23 (2), p.365-375

2004

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Meiotic regulation of the CDK activator RINGO/Speedy by ubiquitin-proteasome-mediated processing and degradation

Nature cell biology, 2006-10, Vol.8 (10), p.1084-1094

2006

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Regulation of Cdc25C Activity During the Meiotic G2/M Transition

Cell cycle (Georgetown, Tex.), 2004-06, Vol.3 (6), p.731-735

2004

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Phosphorylation of EEA1 by p38 MAP kinase regulates μ opioid receptor endocytosis

The EMBO journal, 2005-09, Vol.24 (18), p.3235-3246

2005

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Mechanisms and functions of p38 MAPK signalling

Diversity and versatility of p38 kinase signalling in health and disease

Structural basis of a redox-dependent conformational switch that regulates the stress kinase p38α

P38α/JNK signaling restrains erythropoiesis by suppressing Ezh2-mediated epigenetic silencing of Bim

Characterization of p38α autophosphorylation inhibitors that target the non-canonical activation pathway

Changes in the free-energy landscape of p38α MAP kinase through its canonical activation and binding events as studied by enhanced molecular dynamics simulations

Myeloid p38α signaling promotes intestinal IGF‐1 production and inflammation‐associated tumorigenesis

Multi-phosphorylation of the Intrinsically Disordered Unique Domain of c-Src Studied by In-Cell and Real-Time NMR Spectroscopy

p38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and aging

Lipid binding by the Unique and SH3 domains of c-Src suggests a new regulatory mechanism

Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity

p38 Mitogen-activated protein kinase- and HuR-dependent stabilization of p21(Cip1) mRNA mediates the G(1)/S checkpoint

SnapShot: p38 MAPK Substrates

Characterization of p38α Signaling Networks in Cancer Cells Using Quantitative Proteomics and Phosphoproteomics

Autophagy-induced senescence is regulated by p38α signaling

p38 MAPK Enhances STAT1-Dependent Transcription Independently of Ser-727 Phosphorylation

The Functional Interaction of 14-3-3 Proteins with the ERK1/2 Scaffold KSR1 Occurs in an Isoform-specific Manner

Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions

p38 MAP kinases: beyond the stress response

CDC25B Phosphorylation by p38 and MK-2

Stress signaling boosts interferon-induced gene transcription in macrophages

Phosphorylation of MRF4 transactivation domain by p38 mediates repression of specific myogenic genes

Meiotic regulation of the CDK activator RINGO/Speedy by ubiquitin-proteasome-mediated processing and degradation

Regulation of Cdc25C Activity During the Meiotic G2/M Transition

Phosphorylation of EEA1 by p38 MAP kinase regulates μ opioid receptor endocytosis

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