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Pharmacogenomics in clinical practice and drug development

Nature biotechnology, 2012-11, Vol.30 (11), p.1117-1124

2012

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Lack of adverse clopidogrel-atorvastatin clinical interaction from secondary analysis of a randomized, placebo-controlled clopidogrel trial

Circulation (New York, N.Y.), 2003-08, Vol.108 (8), p.921-924

2003

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Relation of inflammation and benefit of statins after percutaneous coronary interventions

Circulation (New York, N.Y.), 2003-04, Vol.107 (13), p.1750-1756

2003

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Effect of lipid-lowering therapy on early mortality after acute coronary syndromes: an observational study

The Lancet (British edition), 2001-04, Vol.357 (9262), p.1063-1068

2001

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Sustained Local Delivery of Dexamethasone by a Novel Intravascular Eluting Stent to Prevent Restenosis in the Porcine Coronary Injury Model

Journal of the American College of Cardiology, 1997-03, Vol.29 (4), p.808-816

1997

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Bleeding Complications With Dual Antiplatelet Therapy Among Patients With Stable Vascular Disease or Risk Factors for Vascular Disease: Results From the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance (CHARISMA) Trial

Circulation (New York, N.Y.), 2010-06, Vol.121 (23), p.2575-2583

2010

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Prediction of 1-year survival after thrombolysis for acute myocardial infarction in the Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries trial

Circulation (New York, N.Y.), 2000-05, Vol.101 (19), p.2231-2238

2000

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Dual or Mono Antiplatelet Therapy for Patients With Acute Ischemic Stroke or Transient Ischemic Attack: Systematic Review and Meta-Analysis of Randomized Controlled Trials

Stroke (1970), 2012-04, Vol.43 (4), p.1058-1066

2012

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Incidence and predictors of bleeding after contemporary thrombolytic therapy for myocardial infarction

Circulation (New York, N.Y.), 1997-06, Vol.95 (11), p.2508-2516

1997

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Profile and prevalence of aspirin resistance in patients with cardiovascular disease

The American journal of cardiology, 2001-08, Vol.88 (3), p.230-235

2001

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Platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes: a meta-analysis of all major randomised clinical trials

The Lancet (British edition), 2002-01, Vol.359 (9302), p.189-198

2002

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Regional Variation across the United States in the Management of Acute Myocardial Infarction

The New England journal of medicine, 1995-08, Vol.333 (9), p.565-572

1995

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Amplified benefit of clopidogrel versus aspirin in patients with diabetes mellitus

The American journal of cardiology, 2002-09, Vol.90 (6), p.625-628

2002

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Atenolol use and clinical outcomes after thrombolysis for acute myocardial infarction: the GUSTO-I experience

Journal of the American College of Cardiology, 1998-09, Vol.32 (3), p.634-640

1998

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Toward a new frontier in myocardial reperfusion therapy: Emerging platelet preeminence

Circulation (New York, N.Y.), 1998-01, Vol.97 (2), p.211-218

TOPOL, E. J

1998

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Multicenter, randomized, double-blind, placebo-controlled trial of the platelet integrin glycoprotein IIb/IIIa blocker integrelin in elective coronary intervention

Circulation (New York, N.Y.), 1995-04, Vol.91 (8), p.2151-2157

1995

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Increased mortality with oral platelet glycoprotein IIb/IIIa antagonists : A meta-analysis of phase III multicenter randomized trials

Circulation (New York, N.Y.), 2001-01, Vol.103 (2), p.201-206

2001

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Platelet GPIIb-IIIa blockers

The Lancet (British edition), 1999-01, Vol.353 (9148), p.227-231

1999

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Extended mortality benefit of early postinfarction reperfusion

Circulation (New York, N.Y.), 1998-04, Vol.97 (16), p.1549-1556

1998

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Meta-analysis of randomized and registry comparisons of ticlopidine with clopidogrel after stenting

Journal of the American College of Cardiology, 2002-01, Vol.39 (1), p.9-14

2002

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Risk factors, angiographic patterns, and outcomes in patients with ventricular septal defect complicating acute myocardial infarction

Circulation (New York, N.Y.), 2000-01, Vol.101 (1), p.27-32

2000

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Randomized, placebo-controlled trial of platelet glycoprotein IIb/IIIa blockade with primary angioplasty for acute myocardial infarction

Circulation (New York, N.Y.), 1998-08, Vol.98 (8), p.734-741

1998

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Early and sustained survival benefit associated with statin therapy at the time of percutaneous coronary intervention

Circulation (New York, N.Y.), 2002-02, Vol.105 (6), p.691-696

2002

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Randomised placebo-controlled and balloon-angioplasty-controlled trial to assess safety of coronary stenting with use of platelet glycoprotein-IIb/IIIa blockade

The Lancet (British edition), 1998-07, Vol.352 (9122), p.87-92

Topol, Eric J

1998

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Abciximab reduces mortality in diabetics following percutaneous coronary intervention

Journal of the American College of Cardiology, 2000-03, Vol.35 (4), p.922-928

2000

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Pharmacogenomics in clinical practice and drug development

Lack of adverse clopidogrel-atorvastatin clinical interaction from secondary analysis of a randomized, placebo-controlled clopidogrel trial

Relation of inflammation and benefit of statins after percutaneous coronary interventions

Effect of lipid-lowering therapy on early mortality after acute coronary syndromes: an observational study

Sustained Local Delivery of Dexamethasone by a Novel Intravascular Eluting Stent to Prevent Restenosis in the Porcine Coronary Injury Model

Bleeding Complications With Dual Antiplatelet Therapy Among Patients With Stable Vascular Disease or Risk Factors for Vascular Disease: Results From the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance (CHARISMA) Trial

Prediction of 1-year survival after thrombolysis for acute myocardial infarction in the Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries trial

Dual or Mono Antiplatelet Therapy for Patients With Acute Ischemic Stroke or Transient Ischemic Attack: Systematic Review and Meta-Analysis of Randomized Controlled Trials

Incidence and predictors of bleeding after contemporary thrombolytic therapy for myocardial infarction

Profile and prevalence of aspirin resistance in patients with cardiovascular disease

Platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes: a meta-analysis of all major randomised clinical trials

Regional Variation across the United States in the Management of Acute Myocardial Infarction

Amplified benefit of clopidogrel versus aspirin in patients with diabetes mellitus

Atenolol use and clinical outcomes after thrombolysis for acute myocardial infarction: the GUSTO-I experience

Toward a new frontier in myocardial reperfusion therapy: Emerging platelet preeminence

Multicenter, randomized, double-blind, placebo-controlled trial of the platelet integrin glycoprotein IIb/IIIa blocker integrelin in elective coronary intervention

Increased mortality with oral platelet glycoprotein IIb/IIIa antagonists : A meta-analysis of phase III multicenter randomized trials

Platelet GPIIb-IIIa blockers

Extended mortality benefit of early postinfarction reperfusion

Meta-analysis of randomized and registry comparisons of ticlopidine with clopidogrel after stenting

Risk factors, angiographic patterns, and outcomes in patients with ventricular septal defect complicating acute myocardial infarction

Randomized, placebo-controlled trial of platelet glycoprotein IIb/IIIa blockade with primary angioplasty for acute myocardial infarction

Early and sustained survival benefit associated with statin therapy at the time of percutaneous coronary intervention

Randomised placebo-controlled and balloon-angioplasty-controlled trial to assess safety of coronary stenting with use of platelet glycoprotein-IIb/IIIa blockade

Abciximab reduces mortality in diabetics following percutaneous coronary intervention

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