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Long-Term Entecavir Treatment Results in Sustained Antiviral Efficacy and Prolonged Life Span in the Woodchuck Model of Chronic Hepatitis Infection

The Journal of infectious diseases, 2001-11, Vol.184 (10), p.1236-1245

2001

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Antiviral Effects of Lamivudine, Emtricitabine, Adefovir Dipivoxil, and Tenofovir Disoproxil Fumarate Administered Orally Alone and in Combination to Woodchucks with Chronic Woodchuck Hepatitis Virus Infection

Antimicrobial Agents and Chemotherapy, 2008-10, Vol.52 (10), p.3617-3632

2008

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Antiviral l-Nucleosides Specific for Hepatitis B Virus Infection

Antimicrobial Agents and Chemotherapy, 2001-01, Vol.45 (1), p.229-235

2001

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Clevudine Inhibits Hepatitis Delta Virus Viremia: a Pilot Study of Chronically Infected Woodchucks

Antimicrobial Agents and Chemotherapy, 2005-10, Vol.49 (10), p.4396-4399

2005

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Antiviral activity of clevudine [ L-FMAU, (1-(2-fluoro-5-methyl-β, L-arabinofuranosyl) uracil)] against woodchuck hepatitis virus replication and gene expression in chronically infected woodchucks ( Marmota monax)

Hepatology (Baltimore, Md.), 2001, Vol.33 (1), p.254-266

2001

Volltextzugriff (PDF)

Antiviral Effect of Oral Administration of Tenofovir Disoproxil Fumarate in Woodchucks with Chronic Woodchuck Hepatitis Virus Infection

Antimicrobial Agents and Chemotherapy, 2005-07, Vol.49 (7), p.2720-2728

2005

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Antiviral Effect of Orally Administered (−)-β-d-2-Aminopurine Dioxolane in Woodchucks with Chronic Woodchuck Hepatitis Virus Infection

Antimicrobial Agents and Chemotherapy, 2007-09, Vol.51 (9), p.3177-3184

2007

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Effect of Oral Administration of Emtricitabine on Woodchuck Hepatitis Virus Replication in Chronically Infected Woodchucks

Antimicrobial Agents and Chemotherapy, 2000-06, Vol.44 (6), p.1757-1760

2000

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Clevudine therapy with vaccine inhibits progression of chronic hepatitis and delays onset of hepatocellular carcinoma in chronic woodchuck hepatitis virus infection

Antiviral therapy, 2004-12, Vol.9 (6), p.937-952

2004

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Suppression of lamivudine-resistant B-domain mutants by adefovir dipivoxil in the woodchuck hepatitis virus model

Antiviral research, 2004-08, Vol.63 (2), p.115-121

2004

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Antiviral Activities of Oral 1-O-Hexadecylpropanediol-3-Phosphoacyclovir and Acyclovir in Woodchucks with Chronic Woodchuck Hepatitis Virus Infection

Antimicrobial Agents and Chemotherapy, 2000-07, Vol.44 (7), p.1964-1969

2000

Volltextzugriff (PDF)

Enhanced antiviral benefit of combination therapy with lamivudine and famciclovir against WHV replication in chronic WHV carrier woodchucks

Antiviral research, 2000, Vol.45 (1), p.19-32

2000

Volltextzugriff (PDF)

Mutations in the conserved woodchuck hepatitis virus polymerase FLLA and YMDD regions conferring resistance to lamivudine

Antiviral research, 2002-07, Vol.55 (1), p.141-150

2002

Volltextzugriff (PDF)

Antiviral activity and toxicity of fialuridine in the woodchuck model of hepatitis B virus infection

Hepatology (Baltimore, Md.), 1998-07, Vol.28 (1), p.179-191

1998

Volltextzugriff (PDF)

Pharmacodynamics of (−)-β-2′,3′-Dideoxy-3′-Thiacytidine in Chronically Virus-Infected Woodchucks Compared to Its Pharmacodynamics in Humans

Antimicrobial Agents and Chemotherapy, 1998-11, Vol.42 (11), p.2804-2809

1998

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Viral Pharmacodynamic Model for (–)-β-2′,3′-Dideoxy-5-Fluoro-3′-Thiacytidine (Emtricitabine) in Chronically Infected Woodchucks

Antiviral chemistry & chemotherapy, 2002-06, Vol.13 (3), p.165-176

2002

Volltextzugriff (PDF)

Depletion of mitochondrial DNA, destruction of mitochondria, and accumulation of lipid droplets result from fialuridine treatment in woodchucks (Marmota monax)

Laboratory investigation, 1997-01, Vol.76 (1), p.77

1997

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Pharmacokinetics of 1-(2-fluoro-5-methyl-beta-L-arabinofuranosyl)uracil in woodchucks

Antimicrobial Agents and Chemotherapy, 1997-10, Vol.41 (10), p.2184-2187

1997

Volltextzugriff (PDF)

Pharmacokinetics of (-)-2'-3'-dideoxy-3'-thiacytidine in woodchucks

Antimicrobial Agents and Chemotherapy, 1996-03, Vol.40 (3), p.642-645

1996

Volltextzugriff (PDF)

Liver-targeted antiviral nucleosides: Enhanced antiviral activity of phosphatidyl-dideoxyguanosine versus dideoxyguanosine in woodchuck hepatitis virus infection in vivo

Hepatology (Baltimore, Md.), 1996-05, Vol.23 (5), p.958-963

1996

Volltextzugriff (PDF)

Antiviral β-L-nucleosides specific for hepatitis B virus infection

Antiviral chemistry & chemotherapy, 2001, Vol.12, p.119-129

2001

Volltextzugriff (PDF)

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Long-Term Entecavir Treatment Results in Sustained Antiviral Efficacy and Prolonged Life Span in the Woodchuck Model of Chronic Hepatitis Infection

Antiviral Effects of Lamivudine, Emtricitabine, Adefovir Dipivoxil, and Tenofovir Disoproxil Fumarate Administered Orally Alone and in Combination to Woodchucks with Chronic Woodchuck Hepatitis Virus Infection

Antiviral l-Nucleosides Specific for Hepatitis B Virus Infection

Clevudine Inhibits Hepatitis Delta Virus Viremia: a Pilot Study of Chronically Infected Woodchucks

Antiviral activity of clevudine [ L-FMAU, (1-(2-fluoro-5-methyl-β, L-arabinofuranosyl) uracil)] against woodchuck hepatitis virus replication and gene expression in chronically infected woodchucks ( Marmota monax)

Antiviral Effect of Oral Administration of Tenofovir Disoproxil Fumarate in Woodchucks with Chronic Woodchuck Hepatitis Virus Infection

Antiviral Effect of Orally Administered (−)-β-d-2-Aminopurine Dioxolane in Woodchucks with Chronic Woodchuck Hepatitis Virus Infection

Effect of Oral Administration of Emtricitabine on Woodchuck Hepatitis Virus Replication in Chronically Infected Woodchucks

Clevudine therapy with vaccine inhibits progression of chronic hepatitis and delays onset of hepatocellular carcinoma in chronic woodchuck hepatitis virus infection

Suppression of lamivudine-resistant B-domain mutants by adefovir dipivoxil in the woodchuck hepatitis virus model

Antiviral Activities of Oral 1-O-Hexadecylpropanediol-3-Phosphoacyclovir and Acyclovir in Woodchucks with Chronic Woodchuck Hepatitis Virus Infection

Enhanced antiviral benefit of combination therapy with lamivudine and famciclovir against WHV replication in chronic WHV carrier woodchucks

Mutations in the conserved woodchuck hepatitis virus polymerase FLLA and YMDD regions conferring resistance to lamivudine

Antiviral activity and toxicity of fialuridine in the woodchuck model of hepatitis B virus infection

Pharmacodynamics of (−)-β-2′,3′-Dideoxy-3′-Thiacytidine in Chronically Virus-Infected Woodchucks Compared to Its Pharmacodynamics in Humans

Viral Pharmacodynamic Model for (–)-β-2′,3′-Dideoxy-5-Fluoro-3′-Thiacytidine (Emtricitabine) in Chronically Infected Woodchucks

Depletion of mitochondrial DNA, destruction of mitochondria, and accumulation of lipid droplets result from fialuridine treatment in woodchucks (Marmota monax)

Pharmacokinetics of 1-(2-fluoro-5-methyl-beta-L-arabinofuranosyl)uracil in woodchucks

Pharmacokinetics of (-)-2'-3'-dideoxy-3'-thiacytidine in woodchucks

Liver-targeted antiviral nucleosides: Enhanced antiviral activity of phosphatidyl-dideoxyguanosine versus dideoxyguanosine in woodchuck hepatitis virus infection in vivo

Antiviral β-L-nucleosides specific for hepatitis B virus infection

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