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Clinical Pharmacokinetics of Therapeutic Monoclonal Antibodies

Clinical pharmacokinetics, 2010-08, Vol.49 (8), p.493-507

2010

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Practical Guidelines for Therapeutic Drug Monitoring of Anticancer Tyrosine Kinase Inhibitors: Focus on the Pharmacokinetic Targets

Clinical pharmacokinetics, 2014-04, Vol.53 (4), p.305-325

2014

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Oral Anticancer Drugs: Mechanisms of Low Bioavailability and Strategies for Improvement

Clinical pharmacokinetics, 2013-06, Vol.52 (6), p.399-414

2013

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A Phase I and Pharmacological Study with Imidazolium-trans-DMSO-imidazole-tetrachlororuthenate, a Novel Ruthenium Anticancer Agent

Clinical cancer research, 2004-06, Vol.10 (11), p.3717-3727

2004

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Relationship between Single Nucleotide Polymorphisms and Haplotypes in DPYD and Toxicity and Efficacy of Capecitabine in Advanced Colorectal Cancer

Clinical cancer research, 2011-05, Vol.17 (10), p.3455-3468

2011

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Quantitative bioanalysis of peptides by liquid chromatography coupled to (tandem) mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008-09, Vol.872 (1), p.1-22

2008

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Electrospray Ionization Quadrupole Ion-Mobility Time-of-Flight Mass Spectrometry as a Tool to Distinguish the Lot-to-Lot Heterogeneity in N-Glycosylation Profile of the Therapeutic Monoclonal Antibody Trastuzumab

Journal of the American Society for Mass Spectrometry, 2009-11, Vol.20 (11), p.2021-2033

2009

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Quantitative assay for six potential breast cancer biomarker peptides in human serum by liquid chromatography coupled to tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010-02, Vol.878 (5), p.590-602

2010

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A Phase I, Randomized, Open-Label, Parallel-Cohort, Dose-Finding Study of Elacridar (GF120918) and Oral Topotecan in Cancer Patients

Clinical cancer research, 2007-06, Vol.13 (11), p.3276-3285

2007

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Phase I and pharmacokinetic trial of AP5346, a DACH-platinum-polymer conjugate, administered weekly for three out of every 4 weeks to advanced solid tumor patients

Cancer chemotherapy and pharmacology, 2007-09, Vol.60 (4), p.523-533

2007

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A Phase I and Pharmacological Study of the Platinum Polymer AP5280 Given as an Intravenous Infusion Once Every 3 Weeks in Patients with Solid Tumors

Clinical cancer research, 2004-05, Vol.10 (10), p.3386-3395

2004

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Population pharmacokinetics of doxorubicin: establishment of a NONMEM model for adults and children older than 3 years

Cancer chemotherapy and pharmacology, 2013-03, Vol.71 (3), p.749-763

2013

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Pharmacogenetic Screening of CYP3A and ABCB1 in Relation to Population Pharmacokinetics of Docetaxel

Clinical cancer research, 2006-10, Vol.12 (19), p.5786-5793

2006

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Effect of the drug transporters ABCG2, Abcg2, ABCB1 and ABCC2 on the disposition, brain accumulation and myelotoxicity of the aurora kinase B inhibitor barasertib and its more active form barasertib-hydroxy-QPA

Investigational new drugs, 2013-10, Vol.31 (5), p.1125-1135

2013

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Effect of the drug transporters ABCB1, ABCC2, and ABCG2 on the disposition and brain accumulation of the taxane analog BMS-275,183

Investigational new drugs, 2014-12, Vol.32 (6), p.1083-1095

2014

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Effect of inhibition of the FGFR–MAPK signaling pathway on the development of ocular toxicities

Cancer treatment reviews, 2013-10, Vol.39 (6), p.664-672

2013

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Relevance of in vitro and clinical data for predicting CYP3A4-mediated herb–drug interactions in cancer patients

Cancer treatment reviews, 2013-11, Vol.39 (7), p.773-783

2013

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Liquid chromatography-tandem mass spectrometric assay for the light sensitive tyrosine kinase inhibitor axitinib in human plasma

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009-12, Vol.877 (32), p.4090-4096

2009

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Liquid chromatography–tandem mass spectrometric assay for diclofenac and three primary metabolites in mouse plasma

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008-09, Vol.872 (1), p.77-82

2008

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Phase I Dose-Escalation Study of the Pan-HER Inhibitor, PF299804, in Patients with Advanced Malignant Solid Tumors

Clinical cancer research, 2011-03, Vol.17 (5), p.1131-1139

2011

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A phase I, open-label, randomized crossover study to assess the effect of dosing of the MEK 1/2 inhibitor Selumetinib (AZD6244; ARRY-142866) in the presence and absence of food in patients with advanced solid tumors

Cancer chemotherapy and pharmacology, 2011-12, Vol.68 (6), p.1619-1628

2011

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Severe Skin Toxicity in Pediatric Oncology Patients Treated with Voriconazole and Concomitant Methotrexate

Antimicrobial Agents and Chemotherapy, 2013-06, Vol.57 (6), p.2878-2881

2013

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A sensitive combined assay for the quantification of paclitaxel, docetaxel and ritonavir in human plasma using liquid chromatography coupled with tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011-10, Vol.879 (28), p.2984-2990

2011

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Decitabine triphosphate levels in peripheral blood mononuclear cells from patients receiving prolonged low-dose decitabine administration: a pilot study

Cancer chemotherapy and pharmacology, 2012-06, Vol.69 (6), p.1457-1466

2012

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Carboplatin dosing in overweight and obese patients with normal renal function, does weight matter?

Cancer chemotherapy and pharmacology, 2009-06, Vol.64 (1), p.115-122

2009

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Clinical Pharmacokinetics of Therapeutic Monoclonal Antibodies

Practical Guidelines for Therapeutic Drug Monitoring of Anticancer Tyrosine Kinase Inhibitors: Focus on the Pharmacokinetic Targets

Oral Anticancer Drugs: Mechanisms of Low Bioavailability and Strategies for Improvement

A Phase I and Pharmacological Study with Imidazolium-trans-DMSO-imidazole-tetrachlororuthenate, a Novel Ruthenium Anticancer Agent

Relationship between Single Nucleotide Polymorphisms and Haplotypes in DPYD and Toxicity and Efficacy of Capecitabine in Advanced Colorectal Cancer

Quantitative bioanalysis of peptides by liquid chromatography coupled to (tandem) mass spectrometry

Electrospray Ionization Quadrupole Ion-Mobility Time-of-Flight Mass Spectrometry as a Tool to Distinguish the Lot-to-Lot Heterogeneity in N-Glycosylation Profile of the Therapeutic Monoclonal Antibody Trastuzumab

Quantitative assay for six potential breast cancer biomarker peptides in human serum by liquid chromatography coupled to tandem mass spectrometry

A Phase I, Randomized, Open-Label, Parallel-Cohort, Dose-Finding Study of Elacridar (GF120918) and Oral Topotecan in Cancer Patients

Phase I and pharmacokinetic trial of AP5346, a DACH-platinum-polymer conjugate, administered weekly for three out of every 4 weeks to advanced solid tumor patients

A Phase I and Pharmacological Study of the Platinum Polymer AP5280 Given as an Intravenous Infusion Once Every 3 Weeks in Patients with Solid Tumors

Population pharmacokinetics of doxorubicin: establishment of a NONMEM model for adults and children older than 3 years

Pharmacogenetic Screening of CYP3A and ABCB1 in Relation to Population Pharmacokinetics of Docetaxel

Effect of the drug transporters ABCG2, Abcg2, ABCB1 and ABCC2 on the disposition, brain accumulation and myelotoxicity of the aurora kinase B inhibitor barasertib and its more active form barasertib-hydroxy-QPA

Effect of the drug transporters ABCB1, ABCC2, and ABCG2 on the disposition and brain accumulation of the taxane analog BMS-275,183

Effect of inhibition of the FGFR–MAPK signaling pathway on the development of ocular toxicities

Relevance of in vitro and clinical data for predicting CYP3A4-mediated herb–drug interactions in cancer patients

Liquid chromatography-tandem mass spectrometric assay for the light sensitive tyrosine kinase inhibitor axitinib in human plasma

Liquid chromatography–tandem mass spectrometric assay for diclofenac and three primary metabolites in mouse plasma

Phase I Dose-Escalation Study of the Pan-HER Inhibitor, PF299804, in Patients with Advanced Malignant Solid Tumors

A phase I, open-label, randomized crossover study to assess the effect of dosing of the MEK 1/2 inhibitor Selumetinib (AZD6244; ARRY-142866) in the presence and absence of food in patients with advanced solid tumors

Severe Skin Toxicity in Pediatric Oncology Patients Treated with Voriconazole and Concomitant Methotrexate

A sensitive combined assay for the quantification of paclitaxel, docetaxel and ritonavir in human plasma using liquid chromatography coupled with tandem mass spectrometry

Decitabine triphosphate levels in peripheral blood mononuclear cells from patients receiving prolonged low-dose decitabine administration: a pilot study

Carboplatin dosing in overweight and obese patients with normal renal function, does weight matter?

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