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Selection of Retapamulin, a Novel Pleuromutilin for Topical Use

Antimicrobial Agents and Chemotherapy, 2006-11, Vol.50 (11), p.3882-3885

2006

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Stepwise Exposure of Staphylococcus aureus to Pleuromutilins Is Associated with Stepwise Acquisition of Mutations in rplC and Minimally Affects Susceptibility to Retapamulin

Antimicrobial Agents and Chemotherapy, 2007-06, Vol.51 (6), p.2048-2052

2007

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Genetic Characterization of Vga ABC Proteins Conferring Reduced Susceptibility to Pleuromutilins in Staphylococcus aureus

Antimicrobial Agents and Chemotherapy, 2008-12, Vol.52 (12), p.4507-4509

2008

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Indole Naphthyridinones as Inhibitors of Bacterial Enoyl-ACP Reductases FabI and FabK

Journal of medicinal chemistry, 2003-04, Vol.46 (9), p.1627-1635

2003

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Use of the Surgical Wound Infection Model To Determine the Efficacious Dosing Regimen of Retapamulin, a Novel Topical Antibiotic

Antimicrobial Agents and Chemotherapy, 2006-11, Vol.50 (11), p.3886-3888

2006

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Discovery of Aminopyridine-Based Inhibitors of Bacterial Enoyl-ACP Reductase (FabI)

Journal of medicinal chemistry, 2002-07, Vol.45 (15), p.3246-3256

2002

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Defining and Combating the Mechanisms of Triclosan Resistance in Clinical Isolates of Staphylococcus aureus

Antimicrobial Agents and Chemotherapy, 2002-11, Vol.46 (11), p.3343-3347

2002

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1,4-Disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI)

Bioorganic & medicinal chemistry letters, 2001-08, Vol.11 (16), p.2061-2065

2001

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Variable Sensitivity to Bacterial Methionyl-tRNA Synthetase Inhibitors Reveals Subpopulations of Streptococcus pneumoniae with Two Distinct Methionyl-tRNA Synthetase Genes

Antimicrobial Agents and Chemotherapy, 2003-06, Vol.47 (6), p.1784-1789

2003

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Identification of a Series of Tricyclic Natural Products as Potent Broad-Spectrum Inhibitors of Metallo-β-Lactamases

Antimicrobial Agents and Chemotherapy, 2002-06, Vol.46 (6), p.1880-1886

2002

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New benzylidenethiazolidinediones as antibacterial agents

Bioorganic & medicinal chemistry letters, 2003-11, Vol.13 (21), p.3771-3773

2003

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Discovery of a Novel and Potent Class of FabI-Directed Antibacterial Agents

Antimicrobial Agents and Chemotherapy, 2002-10, Vol.46 (10), p.3118-3124

2002

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Inhibitors of bacterial enoyl acyl carrier protein reductase (FabI): 2,9-disubstituted 1,2,3,4-tetrahydropyrido[3,4- b]indoles as potential antibacterial agents

Bioorganic & medicinal chemistry letters, 2001-09, Vol.11 (17), p.2241-2244

2001

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Novel cyclohexyl-amides as potent antibacterials targeting bacterial type IIA topoisomerases

Bioorganic & medicinal chemistry letters, 2011-12, Vol.21 (24), p.7483-7488

2011

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Novel amino-piperidines as potent antibacterials targeting bacterial type IIA topoisomerases

Bioorganic & medicinal chemistry letters, 2011-12, Vol.21 (24), p.7489-7495

2011

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Synthesis and Activity of Analogues of SB-219383: Novel Potent Inhibitors of Bacterial Tyrosyl tRNA Synthetase

The Journal of Antibiotics, 2000/11/25, Vol.53(11), pp.1282-1292

2000

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Nanomolar Inhibitors of Staphylococcus aureus Methionyl tRNA Synthetase with Potent Antibacterial Activity against Gram-Positive Pathogens

Journal of medicinal chemistry, 2002-05, Vol.45 (10), p.1959-1962

2002

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Definition of the heterocyclic pharmacophore of bacterial methionyl tRNA synthetase inhibitors: potent antibacterially active non-quinolone analogues

Bioorganic & medicinal chemistry letters, 2004-08, Vol.14 (15), p.3937-3941

2004

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Optimisation of aryl substitution leading to potent methionyl tRNA synthetase inhibitors with excellent gram-Positive antibacterial activity

Bioorganic & medicinal chemistry letters, 2003-02, Vol.13 (4), p.665-668

2003

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Conformational restriction of methionyl tRNA synthetase inhibitors leading to analogues with potent inhibition and excellent gram-Positive antibacterial activity

Bioorganic & medicinal chemistry letters, 2003-04, Vol.13 (7), p.1265-1268

2003

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Postantibiotic and post-beta-lactamase inhibitor effects of amoxicillin plus clavulanate

Antimicrobial Agents and Chemotherapy, 1996-12, Vol.40 (12), p.2796-2801

1996

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Evaluation of 500 Gram negative isolates to determine the number of major susceptibility interpretation discrepancies between the Vitek and MicroScan Walkaway for 9 antimicrobial agents

Diagnostic microbiology and infectious disease, 1996-09, Vol.26 (1), p.1-6

1996

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Comparison of mupirocin susceptibility of nasal and nonnasal Staphylococcus aureus isolates

Diagnostic microbiology and infectious disease, 1994-11, Vol.20 (3), p.171-174

1994

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Evaluation of the ETS-Related Gene mRNA in Urine for the Detection of Prostate Cancer

Clinical cancer research, 2010-03, Vol.16 (5), p.1572-1576

2010

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Selection of Retapamulin, a Novel Pleuromutilin for Topical Use

Stepwise Exposure of Staphylococcus aureus to Pleuromutilins Is Associated with Stepwise Acquisition of Mutations in rplC and Minimally Affects Susceptibility to Retapamulin

Genetic Characterization of Vga ABC Proteins Conferring Reduced Susceptibility to Pleuromutilins in Staphylococcus aureus

Indole Naphthyridinones as Inhibitors of Bacterial Enoyl-ACP Reductases FabI and FabK

Use of the Surgical Wound Infection Model To Determine the Efficacious Dosing Regimen of Retapamulin, a Novel Topical Antibiotic

Discovery of Aminopyridine-Based Inhibitors of Bacterial Enoyl-ACP Reductase (FabI)

Defining and Combating the Mechanisms of Triclosan Resistance in Clinical Isolates of Staphylococcus aureus

1,4-Disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI)

Variable Sensitivity to Bacterial Methionyl-tRNA Synthetase Inhibitors Reveals Subpopulations of Streptococcus pneumoniae with Two Distinct Methionyl-tRNA Synthetase Genes

Identification of a Series of Tricyclic Natural Products as Potent Broad-Spectrum Inhibitors of Metallo-β-Lactamases

New benzylidenethiazolidinediones as antibacterial agents

Discovery of a Novel and Potent Class of FabI-Directed Antibacterial Agents

Inhibitors of bacterial enoyl acyl carrier protein reductase (FabI): 2,9-disubstituted 1,2,3,4-tetrahydropyrido[3,4- b]indoles as potential antibacterial agents

Novel cyclohexyl-amides as potent antibacterials targeting bacterial type IIA topoisomerases

Novel amino-piperidines as potent antibacterials targeting bacterial type IIA topoisomerases

Synthesis and Activity of Analogues of SB-219383: Novel Potent Inhibitors of Bacterial Tyrosyl tRNA Synthetase

Nanomolar Inhibitors of Staphylococcus aureus Methionyl tRNA Synthetase with Potent Antibacterial Activity against Gram-Positive Pathogens

Definition of the heterocyclic pharmacophore of bacterial methionyl tRNA synthetase inhibitors: potent antibacterially active non-quinolone analogues

Optimisation of aryl substitution leading to potent methionyl tRNA synthetase inhibitors with excellent gram-Positive antibacterial activity

Conformational restriction of methionyl tRNA synthetase inhibitors leading to analogues with potent inhibition and excellent gram-Positive antibacterial activity

Postantibiotic and post-beta-lactamase inhibitor effects of amoxicillin plus clavulanate

Evaluation of 500 Gram negative isolates to determine the number of major susceptibility interpretation discrepancies between the Vitek and MicroScan Walkaway for 9 antimicrobial agents

Comparison of mupirocin susceptibility of nasal and nonnasal Staphylococcus aureus isolates

Evaluation of the ETS-Related Gene mRNA in Urine for the Detection of Prostate Cancer

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